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  • 1
    facet.materialart.
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    German Medical Science; Düsseldorf, Köln
    In:  27. Deutscher Krebskongress; 20060322-20060326; Berlin; DOCOP106 /20060320/
    Publication Date: 2006-04-21
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 2
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Deutscher Kongress für Orthopädie und Unfallchirurgie; 74. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie, 96. Tagung der Deutschen Gesellschaft für Orthopädie und Orthopädische Chirurgie, 51. Tagung des Berufsverbandes der Fachärzte für Orthopädie; 20101026-20101029; Berlin; DOCIN19-956 /20101021/
    Publication Date: 2010-10-22
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 3
    ISSN: 0168-9002
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1433-044X
    Keywords: Key words PLLA • Biofix • Ankle fracture • Sterile sinus ; Schlüsselwörter PLLA • Biofix • Knöchelfraktur • Sterile Knochenhöhle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurde eine randomisierte klinische Prospektivstudie durchgeführt, um den Einsatz von selbstverstärkten absorbierbaren Verbindungen (Biofix) zur Fixierung von Knöchelfrakturen zu bewerten. Mit dieser Studie sollte nachgewiesen werden, daß bei der Fixierung mit Biofix-Stäben und Schrauben die gleichen Ergebnisse erzielt werden wie bei der standardmäßigen AO-Fixierung. Die Biofix-Stäbe und Schrauben bieten folgende Vorteile: Kostensenkung, da keine Nachoperation erforderlich ist, Verhinderung von Spannungsabschirmung und dadurch Reduzierung des Risikos von Knochenporosität. Im Rahmen der Studie wurden Patienten im Alter zwischen 16 und 75 Jahren mit geschlossenen Nichtsplitterfrakturen des Malleolus lateralis und/oder medialis und Luxation der Frakturfragmente von über 2 mm untersucht; 22 Patienten wurden mit Biofix-Stäben und Schrauben behandelt, während die 19 Patienten umfassende Kontrollgruppe mit einer Standardtechnik behandelt wurde. Nach 3, 6 und 12 Monaten wurden Röntgenaufnahmen gemacht. Gleichzeitig erfolgte eine Bewertung der funktionellen Ergebnisse gemäß den Kriterien nach Olerud und Molander. 2 Patienten wurden aus nichtmedizinischen Gründen aus der Testgruppe herausgenommen; 22 vor 2 oder mehr Jahren operierte Patienten (12 aus der Biofix-Gruppe, 10 aus der AO-Gruppe) wurden kontaktiert, um festzustellen, ob sich seit der letzten Untersuchung Komplikationen ergeben haben. In 4 Fällen brach während des Einsetzens eine Biofix-Schraube kurz hinter dem Kopf ab. Das hatte keine negativen Auswirkungen auf die Fixierung der Fraktur. Es traten keine frühen postoperativen Komplikationen auf. Die funktionellen und radiologischen Ergebnisse waren in beiden Gruppen gleich. In 3 Fällen entwickelte sich eine sterile Knochenhöhle auf der Seite, auf der die Schrauben eingesetzt wurden. Biofix-Stäbe und Schrauben aus Polymilchsäure stellen eine gute Alternative für die Fixierung von Knöchelfrakturen dar. Die Verwendung von resorbierbarem Frakturfixierungsmaterial bietet den Vorteil, daß keine Nachoperation zur Entfernung des osteosynthetischen Materials erforderlich ist. Die Langzeitergebnisse sind gut. Es besteht jedoch die Möglichkeit, daß sich eine Gewebereaktion auf das resorbierbare Material entwickelt.
    Notes: Summary A prospective randomized clinical trial was performed to evaluate the use of self-reinforced absorbable composites (Biofix) in the fixation of ankle fractures. The aim of this study was to demonstrate that fixation with Biofix rods and screws is as good as the standard A. O. fixation. The benefits of Biofix rods and screws are: a reduction in costs since no secondary operation is needed, prevention of stress-shielding and thereby diminishing the risk of bone porosity. Patients aged between 16 and 75 years old with closed, non-comminuted fractures of the lateral and/or medial malleolus and dislocation of the fracture fragments greater thean 2 mm were included in the study. 22 patients were treated with Biofix rods and screws and the control group of 19 patients with a standard technique. After 3, 6 and 12 months, rontgenograms were taken. At the same time functional results were evaluated following the criteria of Olerud and Molander. Two patients were withdrawn from the trial for non-medical reasons. 22 patients (12 from the Biofix group, 10 from the AO group) operated two or more years ago were contacted to see if any complications had occured since they were last seen. In 4 cases a Biofix screw broke down just beneath the head during insertion. This did not result in an insufficient fixation of the fracture. There were no early post-operative complications. The functional and rontgenological results in both groups were equal. In three cases a sterile sinus developed at the site of screw insertion. Biofix rods and screws, made of polylactic acid, are a good alternative for the fixation of fractures of the ankle. The use of resorbable fracture fixation material has the advantage that a second operation to remove osteosynthesis material is not necessary. The long term results are good. There is, however, a possibility of development of tissue reaction to the resorbable material.
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  • 5
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Quantitative methods are necessary for an objective evaluation of fracture healing. Three-dimensional computed tomography (CT) for the measurement of callus volume and density could be such a method and was investigated in an animal model. In 23 goats a closed tibial fracture was created and stabilized with a cast. The animals were killed at 2, 4 and 6 weeks for radiographical, CT and biomechanical analysis. From the CT scans a three-dimensional reconstruction of the callus was made to measure its volume and mean density. At 2 weeks the callus volume had already reached its maximum. In contrast, callus density, torsional strength and torsional stiffness increased over time (P 〈 0.0001, analysis of variance, ANOVA). Multiple regression analysis showed that the callus volume was not related to the torsional properties. However, callus density was a significant explanatory variable for both torsional strength (R 2 = 0.72, P 〈 0.0001) and torsional stiffness (R 2 = 0.82, P 〈 0.0001). Therefore, callus density as measured by three-dimensional CT is a predictor of the extent of fracture consolidation. CT with three-dimensional reconstruction of the callus seems a valid technique for the quantification of fracture healing.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1618-2650
    Keywords: Best. von Nitrat in Wasser ; Spektralphotometrie, UV ; flow-injection, 0,5 ml-Proben
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary An UV-spectrophotometric determination of NO¯3 in small samples (0.5 ml) of rain and surface waters is described. A variant of flowinjection analysis is used in combination with an active carbon filter for removal of organic interferences. The accuracy and the reproducibility of the method are generally better than 3%. One determination takes 30 s.
    Notes: Zusammenfassung Eine Methode zur Nitratbestimmung in Proben von 0.5 ml mittels eines UV-spektralphotometrischen Verfahrens in Kombination mit der „flow-injection“ Methode und einem Filter zur Beseitigung organischer Substanzen wird vorgeschlagen. Die Genauigkeit und Reproduzierbarkeit sind meistens besser als 3%. Eine Bestimmung fordert einen Zeitaufwand von 30 s.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-739X
    Keywords: Ceftazidine ; Cefuroxime ; Groin ; Implants, artificial ; Vascular surgery ; Pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The kinetics of systemically and locally administered cefuroxime or ceftazidime in wound fluid were investigated in the period after vascular prosthetic implantation. Cefuroxime or ceftazidime was administered intravenously in patients. Simultaneously 250 mg ceftazidime or cefuroxime was added to preclotted blood. Locally administered antibiotics could not be detected in our samples. In groin fluid samples 24–48 h after the operation the average concentration of cefuroxime was 8.3 and of ceftazidime 5.0 mg/l. The decline of the concentration of cefuroxime or ceftazidime in groin fluid seems to be much slower than one would expect from the half-lives of the antibiotics. We conclude that cefuroxime and to a lesser extent ceftazidime are suitable as prophylactic agents in arterial reconstruction.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0003-2670
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 0003-2670
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1439-6327
    Keywords: Aerobic power ; Anaerobic power ; Training
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Seven female and eight male elite junior skaters performed cycle ergometer tests at four different times during the 1987/1988 season. The tests consisted of a Wingate-type 30-s sprint test and a 2.5-min supramaximal test. The subjects were tested in February, May and September 1987 and in January 1988. Maximal oxygen consumption was measured during the 2.5-min test. With the exception of the maximal oxygen consumption of the women in May which was about 6% lower than in the other three tests, no seasonal changes in the test results could be observed —this, in spite of a distinct increase in training volume (from 10 to more than 20 h · week−1) and training intensity in the course of the season. When the test data were compared to those of elite senior skaters, it appeared that the junior skaters showed the same values for mean power output during the sprint test [14.2 (SD 0.4) W · kg−1 for the men and 12.6 (SD 0.5) W · kg−1 for the women] and maximal oxygen consumption [63.1 (SD 2.8) ml· kg−1 · min−1 for the men and 55.3 (SD 3.5 ml · kg−1 · min−1 for the women, respectively] as found for senior skaters. It seemed, therefore, that the effects of training in these skaters had already levelled off in the period before they participated in this investigation. In contrast to previous studies, no relationship could be shown between the test results and skating performance. This was most likely due to the homogenous character of the groups (mean standard deviations in power and oxygen consumption were only 5%). It was concluded that the present cycle tests used to measure aerobic and anaerobic power were obviously not of use in evaluating seasonal changes in performance in these groups of highly trained athletes.
    Type of Medium: Electronic Resource
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