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  • 1
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    Totowa, N.J. : Humana Press
    Associated volumes
    Call number: QH506:60/84
    Keywords: Cellular signal transduction / Laboratory manuals
    Pages: xiii, 328 p.
    ISBN: 0896034321
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    QH506:60/84 available
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  • 2
    Call number: ATV-MIB:1/127
    Keywords: Mice / Immunology
    Notes: Papers presented at a workshop in Bethesda, Md., Nov. 4-6, 1985 that was sponsored by the National Cancer Institute and the Jackson Laboratory.
    Pages: xvi, 395 p. : ill.
    ISBN: 3540166572
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    ATV-MIB:1/127 departmental collection or stack – please contact the library
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  • 3
    Keywords: Plant Diseases ; Medical virology ; Plant genetics ; Plant Pathology ; Virology ; Plant Genetics and Genomics ; Springer eBooks
    Description / Table of Contents: A Short Note on Reflections and Publications on Citrus Tristeza Virus (CTV) Methodologies -- A Brief Historical Account of the Family Closteroviridae -- Phenotyping Biological Properties of CTV Isolates -- CTV Vectors and Interactions with the Virus and Host Plants -- Tissue Print and Squash Captures Real-Time RT-PCR Method for Direct Detection of Citrus Tristeza Virus (CTV) in Plant or Vector Tissues -- Detection of Citrus Tristeza Virus and Co-Infecting Viroids -- Assessment of Genetic Variability of Citrus Tristeza Virus by SSCP and CE-SSCP -- Identification and Characterization of Resistance-Breaking (RB) Isolates of Citrus Tristeza Virus -- Genotyping Citrus Tristeza Virus Isolates by Sequential Multiplex RT-PCR and Microarray Hybridization in a Lab-On-Chip Device -- Rapid and Sensitive Detection of Citrus Tristeza Virus Using Reverse Transcription-Loop-Mediated Isothermal Amplification (RT-LAMP) Assay -- Amplification and Cloning of Large cDNA Fragments of the Citrus Tristeza Virus Genome -- Bioinformatic Tools and Genome Analysis of Citrus Tristeza Virus -- Analysis of Genotype Composition of Citrus Tristeza Virus Populations Using Illumina Miseq Technology -- Citrus Tristeza Virus: Host RNA Silencing and Virus Counteraction -- Proteomic Response of Host Plants to Citrus Tristeza Virus -- Gene Expression in Citrus Plant Cells Using Helios® Gene Gun System for Particle Bombardment -- Methods for Producing Transgenic Plants Resistant to CTV
    Abstract: This book provides methods and clear protocols for the various technologies available to detect, characterize, and study Citrus tristeza virus (CTV), a member of the genus Closterovirus, family Closteroviridae. Thanks to the highly sensitive and specific diagnostic procedures developed, knowledge of the molecular characteristics, expression strategies, genetic variability, and epidemiology of the virus has improved significantly, as this volume reflects. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Citrus Tristeza Virus: Methods and Protocols serves as an ideal guide for plant pathologists, plant virologists, molecular biologists, and graduate students interested in performing qualitative and quantitative tests as well as recently-developed diagnostic methods in order to find solutions to improve the management of this disease
    Pages: X, 247 p. 50 illus., 36 illus. in color. : online resource.
    Edition: 1st ed. 2019.
    ISBN: 9781493995585
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  • 4
    Call number: QZ200Z:14/28
    Keywords: Versuchstier / Maus
    Pages: S. 391-420.
    Edition: LISTING 4.
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    QZ200Z:14/28 available
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  • 5
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    Cham : Springer International Publishing
    Keywords: Medicine ; Human Genetics ; Ethics ; Medical ethics ; Biomedicine ; Human Genetics ; Theory of Medicine/Bioethics ; Ethics ; Springer eBooks
    Abstract: This book discusses the common principles of morality and ethics derived from divinely endowed intuitive reason through the creation of al-fitr' a (nature) and human intellect (al-€˜áql). Biomedical topics are presented and ethical issues related to topics such as genetic testing, assisted reproduction and organ transplantation are discussed. Whereas these natural sources are God's special gifts to human beings, God́€™s revelation as given to the prophets is the supernatural source of divine guidance through which human communities have been guided at all times through history. The second part of the book concentrates on the objectives of Islamic religious practice ́€“ the maqa' sid ́€“ which include: Preservation of Faith, Preservation of Life, Preservation of Mind (intellect and reason), Preservation of Progeny (al-nasl) and Preservation of Property. Lastly, the third part of the book discusses selected topical issues, including abortion, assisted reproduction devices, genetics, organ transplantation, brain death and end-of-life aspects. For each topic, the current medical evidence is followed by a detailed discussion of the ethical issues involved
    Pages: XV, 267 p. : online resource.
    ISBN: 9783319184289
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  • 6
    Keywords: Medicine ; Pharmaceutical technology ; Pharmacy ; Pediatrics ; Biomedicine ; Pharmaceutical Sciences/Technology ; Pharmacy ; Pediatrics ; Springer eBooks
    Description / Table of Contents: Pediatric Development: Anatomy -- Age, Weight, Body Surface and Stature, Organ Development -- Pediatric Development: Physiology. Enzymes, Drug Metabolism, Pharmacokinetics and Pharmacodynamics -- Pediatric Development – Gastrointestinal -- How to Estimate the Dose to be Given for the First Time to Pediatric Patients -- The Clinical Relevance of Pediatric Formulations -- General Considerations for Pediatric Oral Drug Formulation -- Orosensory Perception -- Flavor Is Not Just Taste: Taste Concealing -- Liquid Formulations -- Paediatric Solid Formulations -- Semi-Solid Formulations -- The Challenge of Automated Compounding -- Pediatric Formulations in Clinical Testing and the Challenge of Final Market Formulation -- Buccal/Sublingual Drug Delivery for the Paediatric Population -- Topical and Transdermal -- Parenteral Liquids for Intravenous and Transdermal Use -- The Challenges of Paediatric Pulmonary Drug Delivery -- Nasal, Ocular and Otic Drug Delivery -- Rectal Drug Delivery -- Intraosseous Infusions in Infants and Neonates -- Compounding for Children – The Compounding Pharmacist -- Food Ingredients -- Excipients and Active Pharmaceutical Ingredients (APIs) -- Clinical Testing in Children -- Pediatric Formulations and Dosage Forms and Future Opportunities: Impact of Regulations in the United States and Implementation of Quality by Design -- Pediatric Pharmaceutical Legislation and its impact on Adult and Pediatric Drug Development: The EU Regulatory View -- Pediatric Pharmaceutical Legislation in USA and EU and their impact on Adult and Pediatric Drug Development -- Checks and Balances in the EU: The Role of the European Ombudsman, with a Focus on the Paediatric Regulation -- The Dangerous Business Of Predicting The Future
    Abstract: As the first book that specifically addresses pediatric formulations in the context of drug development, Pediatric Formulations: A Roadmap covers anatomy and physiology of children as well as the technical state of the art, gives hints about where to find inspiration, and provides a suitable background on the regulatory framework. Existing books on pediatric formulations mainly discuss compounding at the pharmacy. This is not a ́€œhow to formulat逝 textbook for pharmaceutical scientists; the subtitle €œÁ Roadmaṕ€ indicates that we are on a path in largely unexplored territory. It is an attempt to equip the reader with necessary information on how to get started with the appropriate mindset. Among medicinal specialties, pediatrics is a young discipline. The potential dangers of medicine were often underestimated in earlier times. Cough suppressants labeled as ́€œsuitable for children and adultś€ a hundred years ago could kill children as they contained opioids. Since then, a complex framework has evolved, with physicians, pharmacists, drug development companies, generic companies, academic scientists, regulatory authorities, reimbursement organizations, patients and childreń€™s parents as key players. The position of children in our society has changed dramatically during the last century. Children were protected against clinical trials, yet thanks to clinical trials, many more children with cancer survive today. The development of age-adjusted drug formulations is not only a technical challenge. For new drugs today, there are laws both in the United States and the European Union that compel the research-based pharmaceutical industry to also consider children during drug development. One of the major demands of authorities is the development of age-appropriate formulations. Daniel Bar-Shalom is an Associate Professor in Drug Delivery at The Faculty of Health and Medical Sciences, University of Copenhagen. He has a degree in Biology from The Tel-Aviv University (1975), carried research in botany and then graduated from the School of Pharmacy, Hebrew University of Jerusalem (1982). He is a qualified pharmacist and has managed and owned a pharmacy in Haifa where he gained insight into the needs and idiosyncrasies of patients. He moved to Denmark in 1986 and founded Egalet, a drug delivery company where he served until 2007 as Vice President, R&D. He has been a consultant for various pharmaceutical and medical device companies. He is also the inventor of various technologies, holds many patents and has formulated marketed products. His main interests are controlled drug delivery and in particular oral pediatric formulations and geriatric formulations addressing the problem of polypharmacy. Dr. Klaus Rose is CEO of Klausrose Consulting, Switzerland and advises on pediatric drug development and how to comply with FDA and EMA pediatric requirements. He has studied Latin languages, psychology and medicine. After postgraduate clinical training in general medicine in Germany and England, he joined the pharmaceutical industry. He has held various positions in R&D and medical affairs, was Global Head Pediatrics Novartis from 2001 to 2005 and was Global Head Pediatrics Roche from 2005 to 2009. After a year with a regulatory consultancy, he established his own business. Dr. Rose is a frequent speaker on international conferences on pediatric drug development, organizes trainings and publishes on a regular base
    Pages: XV, 439 p. 76 illus., 36 illus. in color. : online resource.
    ISBN: 9781489980113
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  • 7
    Call number: S020:70
    Keywords: Employment re-entry ; Occupational retraining ; Vocational rehabilitation
    Pages: 111 p.
    Signatur Availability
    S020:70 departmental collection or stack – please contact the library
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  • 8
    ISSN: 0888-7543
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An adult patient with severe scoliosis secondary to familial dysautonomia developed dysphagia and recurrent aspirations. Various imaging studies showed a mechanical obstruction of the esophagus due to compression between the spine and the aorta. The patient underwent a gastrostomy and fundoplication, with a significant decrease in symptoms. The case demonstrates one of the possible long-term consequences of untreated scoliosis.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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