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  • 1
    London : Arnold
    Call number: QZ269:166(4)
    Keywords: Neoplasms / radiotherapy
    Pages: viii, 468 p. : ill.
    Edition: 4th ed.
    ISBN: 9780340927731
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    QZ269:166(4) available
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  • 2
    Champaign, Ill : Project Gutenberg
    Keywords: Love poetry, English. ; Sonnets, English.
    ISBN: 0-585-10180-9
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  • 3
    Hoboken, N.J : BiblioBytes
    Keywords: Love poetry. ; English poetry., lcsh
    ISBN: 0-585-05275-1
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  • 4
    Call number: QH506:60/473
    Keywords: Epidemiology ; Epidemiology / Methodology
    Pages: x, 321 p. : ill
    ISBN: 9781588299642
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    QH506:60/473 available
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  • 5
    Sebastopol, Calif. : O'Reilly
    Call number: W190:18
    Keywords: Operating systems (Computers) ; Linux
    Notes: Includes index.
    Pages: iv, 261 p. : ill.
    Edition: 3rd ed.
    ISBN: 9781491927571
    Signatur Availability
    W190:18 departmental collection or stack – please contact the library
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  • 6
    Keywords: Medicine ; Biomedicine ; Molecular Medicine ; Springer eBooks
    Description / Table of Contents: On Framing the Research Question and Choosing the Appropriate Research Design -- Research Ethics for Clinical Researchers -- Definitions of Bias in Clinical Research -- Longitudinal Studies 1: Determination of Risk -- Longitudinal Studies 2: Modeling Data Using Multivariate Analysis -- Longitudinal Studies 3: Data Modeling Using Standard Regression Models and Extensions -- Longitudinal Studies 4: Matching Strategies to Evaluate Risk -- Longitudinal Studies 5: Development of Risk Prediction Models for Patients with Chronic Disease -- Randomized Controlled Trials 1: Design -- Randomized Controlled Trials 2: Analysis -- Randomized Controlled Trials 3: Measurement and Analysis of Patient-Reported Outcomes -- Randomized Controlled Trials 4: Biomarkers and Surrogate Outcomes -- Randomized Controlled Trials 5: Determining the Sample Size and Power for Clinical Trials and Cohort Studies -- Randomized Controlled Trials 6: On Contamination and Estimating the Actual Treatment Effect -- Randomized Controlled Trials 7: Analysis and Interpretation of Quality of Life Scores -- Randomized Controlled Trials 8: Planning, Monitoring, and Execution -- Evaluation of Diagnostic Tests -- Qualitative Research in Clinical Epidemiology -- Health Economics in Clinical Research -- Clinical Genetic Research 1: Bias -- Clinical Genetic Research 2:℗ Genetic Epidemiology of Complex Phenotypes -- Clinical Genetic Research 3: Genetics ELSI (Ethical, Legal and Social Issues) Research -- Evidence-Based Decision Making 1: Critical Appraisal -- Evidence-Based Decision Making 2: Systematic Reviews and Meta-Analysis -- Evidence-Based Decision Making 3: Health Technology Assessment -- Evidence-Based Decision Making 4: Development and Limitations of Clinical Practice Guidelines -- Evidence-Based Decision-Making 5: Translational Research -- Evidence-Based Decision Making 6: Utilization of Administrative Databases for Health Services Research -- Evidence-Based Decision Making 7: Knowledge Translation -- Evidence-Based Decision Making 8: Health Policy, A Primer for Researchers
    Abstract: Focusing on improving the diagnosis, prognosis, and management of human disease, this book takes on the issues of research design, measurement, and evaluation which are critical to clinical epidemiology. This second edition of Clinical Epidemiology: Practice and Methods opens with how best to frame a clinical research question, the ethics associated with doing a research project in humans, and the definition of various biases that occur in clinical research. From there, it continues by examining issues of design, measurement, and analysis associated with various research designs, including determination of risk in longitudinal studies, assessment of therapy in randomized controlled clinical trials, and evaluation of diagnostic tests, and then delves into the more specialized area of clinical genetic research, before concluding with basic methods used in evidence-based decision making including critical appraisal, aggregation of multiple studies using meta-analysis, health technology assessment, clinical practice guidelines, development of health policy, translational research, how to utilize administrative databases, and knowledge translation. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and practical advice to ensure real world success. Comprehensive and authoritative, Clinical Epidemiology: Practice and Methods, Second Edition is intended to educate researchers on how to undertake clinical research and should be helpful not only to medical practitioners but also to basic scientists who want to extend their work to humans, to allied health professionals interested in scientific evaluation, and to trainees in clinical epidemiology
    Pages: XIII, 533 p. 52 illus., 7 illus. in color. : online resource.
    Edition: 2nd ed. 2015.
    ISBN: 9781493924288
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  • 7
    Call number: QZ266.4:112
    Keywords: Hematopoietic stem cells / Transplantation ; Hematopoietic Stem Cell Transplantation ; Postoperative Care / methods ; Postoperative Complications / prevention & control ; Preoperative Care / methods
    Pages: xi, 555 p. : ill.
    ISBN: 978-0-443-10147-2
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    QZ266.4:112 available
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  • 8
    Keywords: Life sciences ; Cell Biology ; Life sciences ; Cell Biology ; Springer eBooks
    Description / Table of Contents: Visualizing Wnt Palmiteoylation in Single Cells -- Monitoring Wnt Protein Acylation Using an In Vitro Cyclo-Addition Reaction -- Biochemical Methods to Analyze Wnt Protein Secretion -- Methods for Studying Wnt Protein Modifications/Inactivations by Extracellular Enzymes, Tiki and Notum -- Probing Wnt Receptor Turnover: A Critical Regulatory Point of Wnt Pathway -- A Simple Method to Assess Abundance of the b-Catenin Signaling Pool in Cells -- Wnt-Dependent Control of Cell Polarity in Cultured Cells -- The Use of Chick Embryos to Study Wnt Signaling/Gradients -- Monitoring Wnt Signaling in Zebrafish Using Fluorescent Biosensors -- Biochemical Analysis of Tankyrase Activity in Zebrafish In Vitro and In Vivo -- Reconstitution of the Cytoplasmic Regulation of the Wnt Signaling Pathway Using Xenopus Egg Extracts -- Delivery of the Porcupine Inhibitor WNT974 in Mice -- Use of Primary Calvarial Osteoblasts to Evaluate the Function of Wnt Signaling in Osteogenesis -- Monitoring Wnt/b-Catenin Signaling in Skin -- The Generation of Organoids for Studying Wnt Signaling -- Methods to Manipulate and Monitor Wnt Signaling in Human Pluripotent Stem Cells -- Directed Endothelial Progenitor Differentiation from Human Pluripotent Stem Cells Via Wnt Activation Under Defined Conditions
    Abstract: Now poised to evaluate the potential in modulating Wnt signaling for therapeutic agendas in cancer, wound healing, and degenerative disease, this book collects protocols from an exciting area of study. The methodologies include using Wnt modulating chemicals in engineering tissues from induced pluripotent and embryonic stem cells, monitoring Wnt transcriptional responses in diverse tissues such as bone and skin, and using specific biochemical markers of Wnt signaling to either screen molecular libraries or evaluate novel reagents. These protocols also leverage unique experimental strengths from five different model organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Wnt Signaling: Methods and Protocols aims to support researchers in understanding Wnt signal transduction in any effort to improve outcomes in regenerative medicine and cancer management
    Pages: XI, 198 p. 45 illus., 32 illus. in color. : online resource.
    ISBN: 9781493963935
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  • 9
    Call number: QZ202:119/9
    Keywords: Mammals / Physiology ; Biological Assay ; Carcinogens ; Cell Transformation, Neoplastic / chemically induced ; Neoplasms / etiology
    Notes: Based on the Symposium on Cell Transformation Assays: Application to Studies of Mechanisms of Carcinogenesis and to Carcinogen Testing held on September 11-13, 1984 at Research Triangle Park, N.C.; sponsored by the National Toxicology Program, National Institute of Environmental Health Sciences.
    Pages: xvi, 461 p. : ill.
    ISBN: 0881671169
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    QZ202:119/9 available
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  • 10
    Sebastopol, Calif. : O'Reilly
    Call number: B110:150
    Keywords: Operating systems (Computers) ; Linux
    Notes: Previous ed.: 2004.
    Pages: iv, 222 p. : ill.
    Edition: 2nd ed.
    ISBN: 9781449316693
    Signatur Availability
    B110:150 departmental collection or stack – please contact the library
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