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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physics Letters A 179 (1993), S. 306-310 
    ISSN: 0375-9601
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0749-6036
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1044-0305
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0789
    Keywords: Microbial biomass ; No-till agrosystem ; Maize ; Fumigation ; Extraction method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary The soil microbial biomass contains important labile pools of C, N, P, and S, and fluctuations in its size and activity can significantly influence crop productivity. In cropping systems where fertilizer use is reduced or eliminated and green-manure legumes are used, nutrient availability is more directly linked to C-cycle dynamics. We observed the fluctuations in microbial biomass C and P, and in microbial biomass activity over three cropping seasons in continuous maize and 2-year maize-wheat-soybean rotation agroecosystems under no-till and reduced-chemical-input management. We estimated the concentrations of microbial C and P using fumigation-incubation and fumigation-extraction techniques for the surface 20 cm of Cecil and Appling series soils (clayey, kaolinitic, thermic, Typic Kanhapludults). There were significant seasonal fluctuations in microbial C and P under all cropping systems. Generally, the magnitude of fluxes and the quantity of microbial C and P tended to be higher in reduced-chemical-input systems due to tillage and incorporation of crop, weed, and legume residues. Over 3 years, the means for microbial C were 435 under reduced-input maize; 289 under no-till maize; 374 und the reduced-input crop rotation; and 288 mg kg-1 soil under the no-till rotation. The means for microbial P were 5.2 under reduced-input maize; 3.5 under no-till maize; 5.0 under the reduced-input rotation; and 3.5 mg kg-1 soil under the no-till rotation. Estimates of microbial activity, derived from CO2−C evolution and specific respiratory activity (mg CO2−C per mg biomass C), suggest that reduced-chemical-input management may cause a larger fraction of the biomass to be relatively “inactive” but may also increase the activity of the remaining fraction over that in no-till. Thus in these specific systems, the turnover of C and P through the microbial biomass with a reduced chemical input to the soil may be higher than under a no-till system.
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  • 5
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Von Willebrand factor (vWF), fibronectin (FN) and 13-hydroxy-octadecadienoic acid (13-HODE) are known to influence the regulation of the adhesive properties of vascular surfaces. In the present study vWF, FN and 13-HODE were comparatively localized in endothelial cells (EC) and in the extracellular matrix (ECM) produced by EC. An indirect immunofluorescent technique was applied to coverslips containing human EC cultures previously fixed and permeabilized following different procedures: A. Alcohol/acetone; B. Paraformaldehyde alone and C. Paraformaldehyde followed by Triton X-100. vWF was observed inside EC (A), on the ECM produced by EC (B) or in EC and ECM (C) depending on the fixation procedures used. FN was mainly localized in the ECM despite the fixation procedures employed. FN was only seen in relation to cell bodies after strong permeabilization (A). Under our experimental conditions 13-HODE was never found in ECM. This latter antigen was observed randomly dispersed in those preparations fixed with alcohol/acetone, indicating that it is probably extracted by this fixative. 13-HODE was detected in granular shaped structures in EC after permeabilization with detergent (C). These results suggest that the cellular localization of vWF and FN is compatible with an adhesive role related to the abluminal side of ECs. 13-HODE was readily observed after mild permeabilization. This finding would be morphologically consistent with its contribution to the regulation of the vessel wall thromboresistance.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Numerische Mathematik 9 (1966), S. 51-54 
    ISSN: 0945-3245
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 29 (1990), S. 16-20 
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusions The majority of studies on fatty acid metabolism, not only via the lipoxygenase pathway, but also via the cyclo-oxygenase pathway, have focused on arachidonic acid. In addition, the majority of the studies have utilized the inhibitor/add-back approach, using exogenous metabolites such as the prostanoids, monohydroxy fatty acids and leukotrienes, and stimulated cells. However, we have explored the possibility that the endothelial cell lipoxygenase metabolite of linoleic acid, specifically, 13 HODE, influences adhesion of a variety of cells implicated in thrombosis, metastasis and inflammation. Albeit, we have until now only demonstrated a correlation between 13 HODE synthesis and maintaining biocompatability between vascular endothelial cells and platelets, tumor cells and leukocytes, our studies provide ample evidence that there is a common relationship between 13 HODE synthesis in vascular wall cells (both endothelial cells and smooth muscle cells), a variety of tumor cells (both human and animal) and leukocytes, and their adhesive interactions with one another. Given that the expression of adhesive sites require an alteration in the cell membrane surface, and, that intracellular 13 HODE inhibition is, in every case, associated with enhanced adhesion, we postulate the intracellular 13 HODE regulates the expression of cell surface adhesive receptors. It is also of interest to note that recent studies in the atherosclerotic-prone Watanabe rabbit are consistant with this hypothesis. Thus, Lawrence et al. [26] found that the atherosclerotic plaque in the Watanabe rabbit wasless, not more, adhesive for platelets than the healthy vessel wall, and Simon et al. [27] found that the same atherosclerotic plaques had increased 15-lipoxygenase activity, consequently, an increased capacity to synthesize linoleic acid into 13 HODE. Studies presently ongoing in our laboratories are focused at identifying the mechanism (s) by which 13 HODE inhibits RGD adhesive site expression and maintains cells less reactive.
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  • 8
    ISSN: 1432-0630
    Keywords: PACS: 61.82.Fk; 79.20.Ds; 78.66.Fd; 78.55.Cr
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. The influence of excimer-laser-assisted surface processing on quantum-well photoluminescence (QW PL) has been investigated in InGaAs/InGaAsP heterostructures capped with a thin layer of In0.53Ga0.47As. The PL mapping measurements carried out on samples before they were processed in a rapid thermal annealer indicated no significant differences in the QW PL signal intensity measured at the excimer-laser-processed sites and in their vicinity. However, a large difference in the QW PL signal, with its intensity significantly enhanced at the laser-processed sites, was observed after 10 s of rapid thermal annealing (RTA) at 750 °C. The largest contrast in the PL signal (an intensity difference up to about 100%) was obtained for a site processed with 50 pulses and a laser fluence of 123 mJ/cm2. The changes in the QW PL signal intensity have been found to coincide with the changes in the surface chemical composition that were detected with Auger electron spectroscopy. The main difference concerns the development of a GaOx layer on the laser-processed In0.53Ga0.47As surface.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Although biologically-derived porcine secretin is approved for the diagnosis of Zollinger–Ellison Syndrome, it is no longer available in the United States. Pure human and porcine secretins have now been synthesized and new drug applications have been filed with the Federal Drug Administration (FDA).〈section xml:id="abs1-2"〉〈title type="main"〉Methods:In the current study we compared secretin testing results in six confirmed Zollinger–Ellison Syndrome patients using the biologically-derived product and both synthetic products (human and porcine) in a three-way, randomized, single-blind Latin-squares crossover study.〈section xml:id="abs1-3"〉〈title type="main"〉Results:Using the FDA-approved criterion for positive secretin testing (i.e. a serum gastrin concentration increase of 〉 110 pg/mL), there was complete agreement between all three agents for all patients. With the more stringent NIH criterion (i.e. a serum gastrin concentration increase of 〉 200 pg/mL), positive results persisted in five out of six, six out of six and four out of six patients using biologically-derived secretin, synthetic porcine secretin, and synthetic human secretin, respectively (six out of six, six out of six and four out of six if a positive test was defined as a 50% increase in serum gastrin concentration). The time to peak serum gastrin concentration after secretin injection occurred within 15 min in all studies (in 94% by 10 min and in 77% by 5 min). Three-way comparisons of serum gastrin concentrations showed a single statistically significant difference (the change from baseline at 15 min between synthetic human and synthetic porcine secretin, P=0.0274). Statistically significant changes from baseline occurred at 1, 2 and 5 min for biologically-derived porcine secretin and at 2 and 5 min for both synthetic porcine and synthetic human secretin, in keeping with the expected time curve for positive tests. All three agents were well-tolerated.〈section xml:id="abs1-4"〉〈title type="main"〉Conclusions:These data suggest that either synthetic secretin product, when released onto the United States market, can be used to confirm Zollinger–Ellison Syndrome.
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  • 10
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Total mercury (Hg) was determined in milk, eggs, beef, pork, human head hair, soil and water obtained from four geographical areas of North Dakota. The sampling areas were selected on the basis of differences in prevalent agricultural practices, climate and topography. Statewide average Hg concentrations in ppb were milk, 0.8; eggs, 12; beef muscle, 5; beef liver, 10; pork muscle, 11; pork liver, 15; head hair, 1708; soil, 30; rainwater and well water, less than one. There were no significant differences observed among areas in Hg content of any substance sampled except beef muscle. Beef muscle obtained from areas 2 and 4 contained significantly (P⩽0.05) higher levels of Hg than beef muscle from the other two areas. However, the magnitudes of differences were small (4 to 6 ppb). Considerable variation among individual beef and swine were noted but only six beef of 453 sampled and three swine of 156 sampled had tissue Hg exceeding 50 ppb. Appreciable variation was observed in Hg in eggs with respect to farms within an area, eggs from the same farm, and sampling times within a year. Few eggs sampled contained more than 50 ppb. Significantly (P⩽0.01) higher levels of Hg were found in head hair of women as compared with men and relatively large differences among individuals were observed. Average Hg in hair was generally low irrespective of sex of donor or area of the state as compared with data given in the literature. Soil Hg levels were consistently low in all areas of the state, and no relationship between cropping practices and soil Hg was detected.
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