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  • 1
    Unknown
    Cold Spring Harbor, NY : Cold Spring Harbor Laboratory Press
    Call number: 04-Gen:248
    Keywords: Genetic transcription / Regulation ; Genetic transcription / Regulation ; Transcription, Genetic ; Eukaryotic Cells ; Transcription Factors ; DNA-Binding Proteins
    Pages: xxix, 640 p. : ill.
    ISBN: 0879695374
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    04-Gen:248 departmental collection or stack – please contact the library
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  • 2
    ISSN: 1573-3521
    Keywords: HIV ; HIV risk behavior ; HIV risk sensitization ; Timeline Followback sexual behavior interview
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Psychology
    Notes: Abstract We administered a detailed structured interview of sexual HIV risk behavior to 110 college students (46% women; mean age = 19.7 years; range = 18–41 years) and assessed their perceived risk of HIV infection before and after the interview. The sexual behavior assessment consisted of 29 single-item frequency questions, followed by a 90-day Timeline Followback interview. Results indicate that sexually active participants experienced HIV risk sensitization during the interview, whereas participants who were not sexually active did not. Among the sexually active participants, those who had multiple sexual partners were more sensitized to their risk than participants with only one partner, and those who engaged in vaginal sex evidenced increased risk perception, but participants who had only oral sex did not. These findings indicate that detailed sexual behavior assessments influence participants' motivation to reduce their risk behavior. This may be helpful in increasing the effectiveness of brief risk behavior interventions such as HIV counseling and testing. These findings may also have implications for the generalizability of HIV prevention interventions to contexts that do not include such detailed assessments.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-3521
    Keywords: diabetes ; appraisal ; stress ; psychometrics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Psychology
    Notes: Abstract The present research evaluated the psychometric properties of a brief self-report instrument designed to assess appraisal of diabetes. Two hundred male subjects completed the Appraisal of Diabetes Scale (ADS) and provided blood samples that were subsequently assayed to provide an index of glycemic control (i.e., glycosylated hemoglobin). Subjects also completed either (a) additional measures of diabetes-related health beliefs, diabetic daily hassles, perceived stress, diabetic adherence, and psychiatric symptoms or (b) the ADS on two additional occasions. Results indicated that the ADS is an internally consistent and stable measure of diabetes-related appraisal. The validity of the measure was supported by correlational analyses which documented the relationship between the ADS and several related self-report measures.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    The VLDB journal 2 (1993), S. 361-406 
    ISSN: 0949-877X
    Keywords: Performance ; simulation models ; B+-tree structures ; resource conditions ; workload parameters ; lock modes ; data contention
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract A number of algorithms have been proposed to access B+-trees concurrently, but they are not well understood. In this article, we study the performance of various B+-tree concurrency control algorithms using a detailed simulation model of B+-tree operations in a centralized DBMS. Our study covers a wide range of data contention situations and resource conditions. In addition, based on the performance of the set of B+-tree concurrency control algorithms, which includes one new algorithm, we make projections regarding the performance of other algorithms in the literature. Our results indicate that algorithms with updaters that lock-couple using exclusive locks perform poorly as compared to those that permit more optimistic index descents. In particular, the B-link algorithms are seen to provide the most concurrency and the best overall performance. Finally, we demonstrate the need for a highly concurrent long-term lock holding strategy to obtain the full benefits of a highly concurrent algorithm for index operations.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0949-877X
    Keywords: Key words: Optimization – Cost models – Join methods – Buffer allocation – Performance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract. In this paper, we re-examine the results of prior work on methods for computing ad hoc joins. We develop a detailed cost model for predicting join algorithm performance, and we use the model to develop cost formulas for the major ad hoc join methods found in the relational database literature. We show that various pieces of “common wisdom” about join algorithm performance fail to hold up when analyzed carefully, and we use our detailed cost model to derive op timal buffer allocation schemes for each of the join methods examined here. We show that optimizing their buffer allocations can lead to large performance improvements, e.g., as much as a 400% improvement in some cases. We also validate our cost model's predictions by measuring an actual implementation of each join algorithm considered. The results of this work should be directly useful to implementors of relational query optimizers and query processing systems.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-3610
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This report describes a community-based cardiovascular risk-reduction program which targeted high-risk individuals. A total of 1,471 individuals participated and were screened for blood pressure, fasting serum cholesterol, blood glucose level, and appearance of the serum. These individuals also completed a questionnaire regarding their knowledge of heart disease. Overall, 522 (35.5%) individuals had a cholesterol level of 240+ mg/dl; 261 (17.7%) had hypertension; 118 (8%) had a glucose level of 120+ mg/100 ml blood; 266 (18.1%) smoked; and the serum was evaluated as “turbid” or “lipemic” in 105 (7.1%). Therefore, of the 1,471 individuals examined, 733 (49.8%) could be considered “at risk” due to the presence of one or more risk factors. Interestingly, 73% of respondents knew their blood pressure, whereas only 15% and 12%, respectively, knew their cholesterol and glucose levels. Eighty percent of the sample knew that smoking, hypertension, and cholesterol were risk factors, but only 50% of the sample identified diabetes as an independent risk factor. Contrary to expectation, knowledge of heart disease and diabetes wasnot related to either initial level or change in cholesterol at 18-month retest. Overall, these results indicate that a community screening program can identify high risk individuals at a relatively low cost, and that knowledge of risk factors and disease is not related to initial risk status or self-initiated change in risk status.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-3254
    Keywords: HIV ; AIDS ; knowledge ; measurement ; assessment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have developed and evaluated a self-administered questionnaire of knowledge about human immunodeficiency virus (HIV) infection for use in program evaluation. Formative work led to the development of the 62-item HIV-Knowledge Questionnaire (HIV-K-Q), which was administered to 409 women and 227 men. Item analyses resulted in the deletion of 17 items that were either too easy or did not correlate well with the total score. Factor analysis on the remaining 45 items resulted in a single factor labeled HIV Knowledge. The generalizability of this one-factor solution was confirmed with data from 285 women and 76 men. Reliability analyses revealed that the HIV-K-Q is internally consistent (alpha = .91) and stable over 1-week (r = .83), 2-week (r = .91), and 12-week (r = .90) intervals. Evidence for the validity of the HIV-K-Q was assembled using known groups and treatment outcome analyses. Additional evidence emerged from analyses that revealed associations between scores on the HIV-K-Q and two related knowledge measures, and between HIV-K-Q scores and level of educational attainment. Discriminant evidence was obtained through nonsignificant relationships between the HIV-K-Q and potentially biasing constructs, including social desirability. The HIV-K-Q requires a sixth-grade education, and 7 min to complete. The HIV-K-Q is a reliable, valid, and practical measure of HIV-related knowledge that can be used with low-literacy adults.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-3254
    Keywords: HIV ; AIDS ; women ; prevention ; qualitative methods
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Focus groups were conducted with 45 young, single, low-income women regarding the human immunodeficiency virus (HIV). Risk in this sample was substantial, as 53% had multiple sexual partners, and 55% reported a recent sexually transmitted disease. Qualitative analysis of transcribed focus groups identified six themes that emerged across groups: (a) misinformation about vertical transmission and treatment of HIV-related illnesses; (b) risk perception linked to emotive factors rather than objective data; (c) uncertainty regarding the risk-reducing value of monogamy; (d) fatalism linked with ambivalence about HIV-antibody testing and treatment; (e) recognition of the importance of discussing HIV-related topics with children, but concern that such discussion with other women might be inappropriate; and (f) inconsistent communication regarding HIV transmission and prevention with partners, partly the result of concerns about violating trust in intimate relationships. These themes warrant attention in the development of HIV risk-reduction programs.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Aids and behavior 3 (1999), S. 269-276 
    ISSN: 1573-3254
    Keywords: HIV ; prevention ; motivation ; skills ; behavior change
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This article advances the view that motivational strategies can augment the effectiveness of skills-based HIV risk reduction interventions. We articulate the empirical and theoretical rationale for a motivational approach and describe how we developed a motivationally based HIV risk reduction intervention. We also describe the strategic exercises and the therapeutic style that constitutes this approach, and then present detailed reviews of three clinical trials that have evaluated HIV-preventive motivational interventions. Results of these trials provide promising evidence for the integration of motivational approaches with traditional skills-based approaches. We recognize the limitations of existing research and provide suggestions for future investigations.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-3327
    Keywords: Adoption ; International ; Psychosocial ; Adjustment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study compared a small group of Korean-American adoptees with their adoptive siblings who are biological children of the adoptive parents with respect to their psychosocial adjustment. Eighteen Korean-American adoptees were compared with nine biological children by a structured demographic, medical, clinical survey form and the Child Behavior Checklist-Parent Form (CBCL-P). The parents did not raise any more concerns about the adjustment of adopted children than their biological children. On the CBCL-P, the two groups did not differ significantly in competence T-scores, total behavioral problems, broad band T-scores and the total number of problem behaviors except for lower social competence in adopted children and a higher internalization score in biological children. In conclusion, the international adoptees, the Korean-American children have adjusted well during their early childhood after early adoption. Further studies employing a larger sample are warranted to better understand the international adoption practice.
    Type of Medium: Electronic Resource
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