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  • 1
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    Boston, Mass : Harvard Business School Press
    Keywords: Market segmentation. ; New products.
    Notes: Creating blue oceans -- Analytical tools and frameworks -- Reconstruct market boundaries -- Focus on the big picture, not the numbers -- Reach beyond existing demand -- Get the strategic sequence right -- Overcome key organizational hurdles -- Build execution into strategy -- The sustainability and renewal of blue ocean strategy
    Pages: xv, 240 p.
    ISBN: 1-417-58905-1
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  • 2
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    Hershey, PA : Idea Group Pub
    Keywords: Business logistics.
    Notes: A co-ordinated single-vendor multi-buyer supply chain model : synchronisation of ordering and production cycles / Chi Kin Chan, Brian G. Kingsman -- Multi-stage efficiency tools for goal setting and monitoring in supply chains / Marvin D. Troutt, Paul J. Ambrose, Chi Kin Chan -- Optimal feedback production for a supply chain / K.H. Wong, H.W.J. Lee, and Chi Kin Chan -- Life cycle considerations for supply chain strategy / Toru Higuchi, Marvin D. Troutt, and Brian A. Polin -- The effect of payment terms on order : instability in a supply chain / I. Nyoman Pujawan -- Supply chain globalization and the complexities of cost-minimization strategies / Brian A. Polin, Marvin D. Troutt, and William Acar -- Genetic algorithm & other meta-heuristics : the essential tools for solving modern supply chain management problems / Bernard K-S. Cheung -- Understanding and managing the intrinsic dynamics of supply chains / Toru Higuchi, Marvin D. Troutt -- Re-engineering of logistics activities for electronic commerce / Nathalie Marcoux, Diane Riopel, and André Langevin -- Studies on interaction and coordination in supply chains with perishable products : a review / Xiping Song, Xiaoqinag Cai, Jian Chen
    Pages: 1 v. (various pagings)
    ISBN: 1-591-40305-7
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  • 3
    Keywords: Medicine ; Human Genetics ; Biochemistry ; Cytology ; Biomedicine ; Human Genetics ; Cell Biology ; Biochemistry, general ; Springer eBooks
    Description / Table of Contents: Preface -- The GW body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology -- The Discovery of GW Bodies -- The Discovery and Analysis of P Bodies -- Autoantibodies to Argonaute 2 (Su antigen) -- GW/P Bodies and Autoimmune Disease -- Function of GW182 and GW Bodies in siRNA and miRNA Pathways -- Post-Transcriptional Stimulation of Gene Expression by MicroRNAs -- Gawky (Gw) is the Drosophila Melanogaster GW182 Homologue -- The Role of GW182 Proteins in miRNA-mediated Gene Silencing -- Quantifying Argonaute Proteins in and out of GW/P-bodies: Implications in microRNA Activities -- Deadenylation and P-bodies -- Relationship of GW/P-bodies with Stress Granules -- Relationship of other Cytoplasmic Ribonucleoprotein (RNP) Bodies to GW/P Bodies -- A SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182 -- Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research -- Index
    Abstract: GW bodies are novel cytoplasmic foci that were discovered and named by Dr. Chań€™s group in 2002.℗ These bodies are now known to be active cytoplasmic foci involved with the new gene regulation process mediated by microRNA that leads to translational repression and mRNA degradation.℗ The detailed biological functions of these cytoplasmic structures are still being uncovered and the idea for this book is to provide the history of the discovery and the major work from different laboratories that has led to the characterization and elucidation of the structure and function of these new multiple subcellular structures
    ISBN: 9781461451075
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  • 4
    Call number: F065:4
    Keywords: Polymerase Chain Reaction / methods
    Description / Table of Contents: Introduction to the polymerase chain reaction / Y.M. Dennis Lo and K.C. Allen Chan -- Setting up a polymerase chain reaction laboratory / Y.M. Dennis Lo and K.C. Allen Chan -- Real time polymerase chain reaction and melting curve analysis / Robert J. Pryor and Carl T. Wittwer -- Qualitative and quantitative polymerase chain reaction-based methods for DNA methylation analyses / Ivy H.N. Wong -- In-cell polymerase chain reaction: strategy and diagnostic applications / T. Vauvert Hviid -- Qualitative and quantitative DNA and RNA analysis by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry / Chunming Ding -- Analysis of polymerase chain reaction products by denaturing high performance liquid chromatography / Ching-Wan Lam -- Use of real time polymerase chain reaction for the detection of fetal aneuploidies / Bernhard Zimmermann ... [et al.] -- Noninvasive prenatal diagnosis by analysis of fetal DNA in maternal plasma / Rossa W. K. Chiu and Y. M. Dennis Lo --
    Pages: x, 200 p. : ill.
    Edition: 2nd ed.
    ISBN: 1588293483
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    F065:4 departmental collection or stack – please contact the library
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  • 5
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    Call number: ERW
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    ERW in acquisition
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  • 6
    Keywords: Medicine ; Diagnosis, Ultrasonic ; Internal Medicine ; Cardiology ; Medicine & Public Health ; Cardiology ; Ultrasound ; Internal Medicine ; Springer eBooks
    Pages: : digital
    ISBN: 9781849963879
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  • 7
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    New York : Springer
    Call number: QZ365WS200:35
    Keywords: Neoplasms / diagnosis ; Neoplasms / therapy ; Child ; Infant
    Pages: xv, 287 p. : ill.
    ISBN: 0387244700
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    QZ365WS200:35 available
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  • 8
    Keywords: Life sciences ; Agriculture ; Climatic changes ; Soil conservation ; Life sciences ; Agriculture ; Climate Change ; Soil Science & Conservation ; Springer eBooks
    Pages: : digital
    ISBN: 9783642202568
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  • 9
    Keywords: Medicine ; Pharmacy ; Cancer Research ; Medicine / History ; Biomedicine ; Cancer Research ; Pharmacy ; History of Medicine ; Springer eBooks
    Description / Table of Contents: Part ́… . A Scientific Overview on Cancer -- 1. Advancements in Life Sciences and Characteristic Features of Cancer Cells -- 1.1́€‚Characteristics of cancer cells -- 1.2́€‚Characteristic interactions of cancer cells with neighboring cells and the tumor microenvironment -- 2. Advancement of the Science and History of Cancer and Anticancer Drugs -- Part ́…Ł. Cancer Drug Discovery ́€“ Types and History -- 3. Chronology of Anticancer Drug Development -- 3.1€‚Á historical background of cancer chemotherapy -- 3.2́€‚Development of the anticancer drug screening systems -- 3.3́€‚Chronology of the anticancer drug development -- 3.4 Clinical application of anticancer drugs -- 4.€‚Álkylating Anticancer Drugs -- 4.1́€‚Classical alkylating drugs -- 4.2 Nonclassical alkylating drugs -- 4.3 Alkylating-like agents: platinum compounds -- 5. Antimetabolic Anticancer Drugs -- 5.1 Folic acid derivatives -- 5.2 Purine analogs -- 5.3 Pyrimidine analogs -- 6. Natural Product Anticancer Drugs -- 6.1́€‚Plant-derived anticancer drugs -- 6.2€‚Ánticancer antibiotics -- 7.€‚Ímmunotherapeutic Anticancer Drugs and Other Miscellaneous Anticancer Drugs -- 7.1€‚Ímmunotherapeutic anticancer drugs -- 7.2€‚Óther miscellaneous anticancer drugs -- 8. Hormonal Anticancer Drugs -- 8.1 Hormonal anti-prostate-cancer drugs -- 8.2 Hormonal anti-breast-cancer drugs -- 8.3 Other hormonal anticancer drugs -- 9.́€‚Molecular Targeted Anticancer Drugs -- 9.1́€‚Tretinoin (all-trans retinoic acid, ATRA) -- 9.2́€‚Bcr-Abl Inhibitors -- 9.3 EGFR inhibitors -- 9.4́€‚HER2 inhibitors -- 9.5€‚Ángiogenesis inhibitors -- 9.6€‚Óther kinase inhibitors -- 9.7́€‚mTOR inhibitors -- 9.8 Other targeted anticancer antibody drugs -- 9.9€‚Épigenetic anticancer drugs -- 9.10́€‚Proteasome inhibitors -- 9.11́€‚Vismodegib: hedgehog pathway blocker -- 10. Complications of Anticancer Drugs and Their Management -- 10.1 Chemotherapy-induced nausea and vomiting (CINV) -- 10.2 Myelotoxicity (bone marrow toxicity) -- 10.3 Chemotherapy-induced diarrhea -- 10.4 Chemotherapy-induced constipation -- 10.5 Chemotherapy-induced urinary toxicity -- 10.6 Chemotherapy-induced pulmonary toxicity -- 10.7 Chemotherapy-induced neurotoxicity -- 10.8 Chemotherapy-induced neurotoxicity -- 10.9 Chemotherapy-induced oral mucositis -- 10.10 Anorexia -- 10.11 Tumor lysis syndrome -- 10.12 Extravasation of anticancer drugs -- 10.13 Chemotherapy-induced skin toxicity -- Part ́…Ø. A Paradigm Shift in Cancer Research -- 11. Advancements in Bioscience and New Cancer Drugs -- 11.1. Development of cancer drugs according to scientific advancements -- 11.2. New anticancer drugs
    Abstract: This book describes the history of cancer drugs development to provide insight into the successes and the shortcomings of this enterprise. Most cancer drug treatments target the cancer cell as the core component and as such are very effective in inhibiting their proliferation. However, these cancer drugs are generally ineffective against metastasis, which are tightly linked to the whole body as a system. This book illustrates the problems in cancer drug design and suggests a more systemic view of cancer with a more adapted research approach. The reader will discover a comprehensive and multifaceted overview of the history of the development of anticancer drugs, which has been deeply influenced by the ‘cell concept’ of cancer. Future directions for the development of new anticancer drugs will also be presented. This book has been separated into three sections, providing an overview of: - The scientific progress in the biological sciences over the last 60 years and the influence this progress has had in cancer research. Summaries and charts of important discoveries complete this overview - The process of anticancer drug development with a focus on the characteristic drug groups of each era, illustrated by comprehensive timelines and conceptual cartoons - The limitations of the current cancer drug development pipelines and the new directions for cancer drug discovery, considering a more systemic view of cancer This book is a useful reference for scientists and clinicians working in the biomedical field and for oncologists aiming to explore the landscape of human endeavor in the fight against cancer
    Pages: XVII, 276 p. 138 illus., 134 illus. in color. : online resource.
    ISBN: 9789402408447
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  • 10
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    Oxford : Oxford University Press
    Call number: E020:45
    Keywords: Solid-phase synthesis ; Peptides / Synthesis
    Pages: xxiv, 346 p. : ill.
    Edition: Reprinted
    ISBN: 0199637245
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    E020:45 departmental collection or stack – please contact the library
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