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  • 1
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The limitations and the indications of cerebral scintigraphy using 1131 labelled macroaggregates of serum albumen injected directly into the carotid are examined. The investigation was carried out in a total of 101 patients with benign and malignant tumours, haematomata, cystic lesions, and cerebral vascular insufficiency. The authors raise the possibility that this technique might be useful in the elucidation of the pathophysiology of the cerebral arteriolar and capillary circulation as well as in the evaluation of the efficacy of the collateral circulation when the carotid is occluded. The authors celieve that cerebral scintigraphy using MAA-I131 can be regarded as a useful complementary diagnostic procedure.
    Abstract: Résumé Les auteurs examinent les indications et les limites de la scintigraphie cérébrale à l'aide de macroagrégat d'albumine sérique marqué à l'iode 131 et injecté directement dans la carotide. Ils décrivent la façon de procéder dans 101 cas de: tumeurs bénignes et malignes, hématomes, kystes, lésions cérébrales par insuffisance circulatoire, et analysent les résultats obtenus. En outre, les auteurs envisagent la possibilité d'une utilisation de la méthode scintigraphique dans l'étude de la physio-pathologie de l'arbre cérébral artériolo-capillaire, ainsi que dans l'appréciation de la capacité de la circulation collatérale en cas d'occlusion de la carotide. Les auteurs déclarent, en s'appuyant sur leur expérience, que la scintigraphie à l'aide de MAA-J131 peut être considérée comme un examen complémentaire utile pour le diagnostic en neurologie.
    Notes: Zusammenfassung Es wird über den Wert und die Resultate der Hirnszintigraphie mit Jod131-markierten Eiweißmakroaggregaten aus denaturiertem Humanserumalbumin (MAA-J131) bei intraarterieller Injektion in die A. carotis berichtet. Diese Methode wurde bei 101 Patienten mit gutartigen und bösartigen Tumoren, Hämatomen, zystischen Prozessen und zerebralen Durchblutungsstörungen durchgeführt. Außerdem werden die Möglichkeiten aufgezeigt, mit Hilfe dieser Methode Aufschlüsse über die Pathophysiologie der Hirndurchblutung im Bereiche der Arterien und der Kapillaren sowie über die kollateralen Durchblutungsverhältnisse bei Karotisverschlüssen zu gewinnen. Die Methodik wird beschrieben. Die Verfasser betonen, daß sich die Hirnszintigraphie mit MAA-J131 als wertvolle zusätzliche neurodiagnostische Methode bewährt hat.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Cerebral vasospasm ; subarachnoid haemorrhage ; intracranial aneurysms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An investigation was carried out in 28 patients in order to evaluate the relationship between angiographically documented vasospasm, amount of subarachnoid blood found at surgery around ruptured intracranial aneurysms, and delayed ischaemic deficits. Angiography was performed at time intervals ranging between 5 and 17 days, and surgery not later than 21 days following subarachnoid haemorrhage. The absence of subarachnoid clots was associated in ten patients, with no or minor vasospasm and no or mild neurological deficits. Thin clots were found in eight patients; one of them had no vasospasm, six had minor vasospasm, and one showed severe vessel narrowing. Major clinical signs were absent in these cases. All ten patients with thick clots developed severe vasospasm, and eight of them severe neurological signs. The important aetiological role of local subarachnoid clots in determining vasospasm is emphasized in view of surgical timing.
    Type of Medium: Electronic Resource
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