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  • 1
    facet.materialart.
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ); 20170920-20170923; Münster; DOC079 /20171124/
    Publication Date: 2017-11-24
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 2
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  51. Kongress für Allgemeinmedizin und Familienmedizin; 20170921-20170923; Düsseldorf; DOC17degam281 /20170905/
    Publication Date: 2017-09-05
    Keywords: Feedback ; kompetenzorientierte Prüfungen ; Untersuchungstechniken ; ddc: 610
    Language: German
    Type: conferenceObject
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 4 (1990), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: An msDNA operon, consisting of genes for msDNA and a reverse transcriptase, is present in Escherichia coli B and absent from E. coli K12. We have found that the msDNA operon is located on a DNA fragment, longer than 15 kb, that is absent from E. coli K12. Using conjugation, P1 transduction, and nucleic acid hybridization between E. coli B and E. coli K12 strains, we have located the position of the msDNA operon on the E. coli B chromosome at a site that corresponds to minute 19 on the genetic map and to position 900 on the physical map of the E. coli K12 chromosome.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 3 (1989), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Reverse transcriptase, discovered in 1970 in retroviruses, has until recently been found only in eukaryotic organisms. Recently it was shown to occur in two groups of bacteria: myxobacteria and Escherichia coli. The gene for reverse transcriptase is part of a chromosomal genetic element that codes for the production of a branched DNA-RNA compound. In this compound a single-stranded DNA is connected to RNA at a specific G residue by a 2′-5’phosphodiester linkage. The precursor for the DNA-RNA compound is a folded messenger RNA, in which the specific G residue is the initiation point for reverse transcription. In the final DNA-RNA compound, the portion of the RNA transcribed by reverse transcriptase is eliminated by RNase H. The DNA-RNA compound is present in several hundred copies per cell. Its biological function is unknown at present.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0797
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract Tryptophan synthesis was investigated in a two-phase system employing an organic liquid membrane. A diffusion cell was constructed to study the transport of the various components of the reaction through an organic layer of cyclohexane. The organic phase was supported by two polymeric membranes, and Aliquat-336 was used as the anion exchanger. A differential in pH was maintained between the aqueous phases to facilitate extraction of the product from the reaction phase. A mathematical model was developed to estimate effective diffusivities and predict the sensitivity of the system to changes in the partition coefficients and liquid membrane thickness. The use of liquid membrane emulsion-type reactors is discussed.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0827
    Keywords: Structure ; Poly(glycol monomethacrylate) ; Gel ; Implants ; Calcification
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Abstract L'effet de la structure physique et des modification chimiques de gels de poly(glycol monométhacrylate) sur la calcification d'implants tests a été étudié. Alors que les modifications chimiques du poly(glycol monométhacrylate) osseux, obtenu par introduction de groupes formateurs d'ions, n'affectent pas le processus de calcification, on observe un effet net de la structure physique du polymère par action du rapport monomère: eau sur le processus de calcification des implants. Des gels homogènes et microporeux montrent rarement une calcification autor de l'implant; dans les gels macroporeux, la calcification s'observe massivement autour de l'implant, en cas de porosité élevée en son centre. Ce phénomène a été expliqué par la pénétration diverse par du tissu néoformé ainsi que par la possibilité de pénétration d'éléments nutritifs cellulaires, liée à la porosité de l'implant.
    Abstract: Zusammenfassung Die Wirkung der physikalischen Struktur und der chemischen Veränderung von Poly-(Glycol-Monomethacrylat)-Gelen auf die Verkalkung von Implantat-Proben wurde untersucht. Die chemische Veränderung der Poly(Glycol-Monomethacrylat)-Grundstruktur, hervorgerufen durch das Beifügen ionogener Gruppen, hatte auf den Verkalkungsprozeß keine Wirkung; die physikalische Struktur des Polymers hingegen hatte eine markante Wirkung auf den Verkalkungsprozeß der Implantate, welche durch das Verhältnis Monomer: Wasser bestimmt wurde. Homogene und kleinporöse Gele zeigten ganz ausnahmsweise eine Verkalkung am Rande des Implantats; in großporösen Gelen erfolgte massive Verkalkung am Rande des Implantats, bei höherer Porosität in dessen Zentrum. Dieses Phänomen wird zurückgeführt auf den unterschiedlichen Grad, in welchem das neu gebildete Gewebe das Implantat durchdringt und auf die verschiedene Zugänglichkeit der Nahrung der eindringenden Zellen, welche von der Porosität des Implantats abhängt.
    Notes: Abstract The effect of the physical structure and chemical modification of poly(glycol monomethacrylate) gels on the calcification of test implants has been studied. While the chemical modification of the poly(glycol monomethacrylate) backbone by the introduction of ionogenic groups did not affect the process of calcification, there was a substantial effect of the physical structure of the polymer, as determined by the monomer: water ratio, on the process of calcification of the implants. Homogenous and microporous gels showed calcification in the margin of the implant only exceptionally; in macroporous gels calcification occurred massively in the margin of the implant and in the case of a higher porosity in its centre. This phenomenon has been explained by the different degree to which the implant is penetrated by the newly formed tissue, as well as by the difference in accessibility of nutrition to the penetrating cells depending on the porosity of the implant.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0649
    Keywords: PACS: 42.65.Ky; 42.65.An; 78.66 -w
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: 0.9 Ge0.1(001)/Si(001) films with SH photon energies 3.1〈2hν〈3.5 eV near the bulk E1 critical point of Si(001) or Si0.9Ge0.1(001). Ge was deposited on Si(001) by using atomic layer epitaxy cycles with GeH4 or Ge2H6 deposition at 410 K followed by hydrogen desorption. As Ge coverage increased from 0 to 2 monolayers the SH signal increased uniformly by a factor of seven with no detectable shift in the silicon E1 resonant peak position. SH signals from Si0.9Ge0.1(001)/Si(001) were also stronger than those from intrinsic Si(001). Hydrogen termination of the Si0.9Ge0.1(001) and Ge/Si(001) surfaces strongly quenched the SH signals, which is similar to the reported trend on H/Si(001). We attribute the stronger signals from Ge-containingsurfaces to the stronger SH polarizability of asymmetric Ge-Si and Ge-Ge dimers compared to Si-Si dimers. Hydrogen termination symmetrizes all dimers, thus quenching the SH polarizability of all of the surfaces investigated.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In der normalen Mittelohrschleimhaut des Meerschweinchens und des Menschen wurden auf Grund histochemischer and elektronenmikroskopischer Untersuchungen verschiedene Typen von Drüsenzellen festgestellt. Beim Meerschweinchen finden sich Becherzellen, Intermediärzellen and dunkel granulierte Zellen, beim Menschen nur die beiden ersten Typen. Becherzellen entsprechen der sero-mukosen, Intermediärzellen and dunkel granulierte Zellen der serösen (nicht-mukösen) Kategorie des vonShackleford u.Klapper angegebenen Klassifizierungsschemas der Speicheldriisen der Säugetiere.
    Notes: Summary A combined histochemical. and electronmicroseopie approach was used to study secretory cells in the normal middle ear mucosa in guinea-pigs and man. In the guinea-pig the following cell types could be identified: goblet cells, intermediary cells and dark granulated cells. In the human tympanic mucosa only goblet cells and intermediary cells were observed. According to their histochemical properties, goblet cells correspond to the seromucous category, while intermediary and dark granulated cells fall into the serous (non-mucous) category ofShackleford andKlapper's classification of secreting units in mammalian salivary gland.
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  • 10
    ISSN: 1420-908X
    Keywords: Key words: Neutrophil inhibitory factor (NIF) — Neutrophils — Cell adhesion — Mac-1
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Objective and Design: Peptides derived from neutrophil inhibitory factor (NIF), a known antagonist of Mac-1, were evaluated as inhibitors of neutrophil adherence.¶Material: In vitro assays of adherence employed: 1) human polymorphonuclear cells (PMN), 2) human umbilical vein endothelial cells (HUVEC), and 3) CHO cells expressing ICAM-1 (CHO-ICAM cells).¶Treatment: Cells, pretreated with NIF-derived peptides (0.1–100 μM) for 10 minutes, were permitted to adhere for 20 min in the continued presence of peptide.¶Methods: Cell-based assays: 1) PMN adherence to HUVEC, 2) PMN adhesion to immobilized human serum proteins, and 3) adherence of CHO-ICAM cells to immobilized Mac-1.¶Results: A NIF-derived peptide of 29 amino acids blocked PMN adherence to HUVEC, but behaved somewhat differently than the parent NIF protein. NIF specifically antagonized Mac-1 dependent adherence, but the peptide blocked neutrophil adherence that was dependent upon both Mac-1 and LFA-1 integrins. CHO-ICAM adherence to Mac-1 was blocked by NIF, but not by the peptide. Binding studies with NIF and the peptide indicate that the molecules bind to different sites.¶Conclusions: A peptide derived from NIF blocks PMN adherence but, unlike NIF, the mechanism of action is not mediated by direct antagonism Mac-1.
    Type of Medium: Electronic Resource
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