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  • 1
    Call number: M100:479
    Keywords: Clinical Medicine ; Research
    Notes: Transl. of: Testing treatments. 2. ed.
    Pages: 260 p. : ill.
    ISBN: 9783456852454
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  • 2
    Unknown
    Washington, D.C : World Bank
    Keywords: World Bank. ; Economic assistance, Developing countries, Evaluation. ; Poverty, Developing countries.
    Pages: xxiv, 61 p.
    ISBN: 0-585-41509-9
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  • 3
    Unknown
    Berkeley : University of California Press
    Keywords: Agglomérations urbaines, Cas, Études de. ; Metropolitan areas, Case studies. ; Urbanisation, Cas, Études de. ; Urbanization, Case studies.
    Notes: Introduction: looking for agents of urban livability in a globalized political economy / Peter Evans -- Urban poverty and the environment: social capital and state-community synergy in Seoul and Bangkok / Mike Douglass, Orathai Ard-am, and Ik Ki Kim -- Collective action toward a sustainable city: citizens' movements and environmental politics in Taipei / Hsin-Huang Michael Hsiao and Hwa-Jen Liu -- Community-driven regulation: toward an improved model of environmental regulation in Vietnam / Dara O'Rourke -- Social and spatial inequalities in Hungarian environmental politics: a historical perspective / Zsuzsa Gille -- "Water, water, everywhere, nor any drop to drink": land use and water policy in São Paulo, Brazil / Margaret E. Keck -- Sustainability, livelihood, and community mobilization in the Ajusco "ecological reserve" / Keith Pezzoli -- Political strategies for more livable cities: lessons from six cases of development and political transition / Peter Evans
    Pages: xiii, 277 p.
    ISBN: 1-417-52008-6
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  • 4
    Unknown
    Oxford : Oxford University Press
    Call number: B110:64
    Keywords: Stem Cells / physiology ; Embryo, Mammalian / physiology ; Mice ; Models, Animal
    Description / Table of Contents: Procedures for deriving ES cell lines from the mouse / Frances A. Brook -- Production of ES cell-derived mice / Yoko Kato and Yukio Tsunoda -- Generating animal models of human mitochondrial genetic disease using mouse ES cells / Grant R. MacGregor ... [et al.] -- Controlling the differentiation of mouse ES cells in vitro / Michael V. Wiles and Gabriele Proetzel -- In vitro differentiation of mouse ES cells into muscle cells / Yelena S. Tarasova ... [et al.] -- In vitro differentiation of mouse ES cells into haematopoietic cells / Osamu Ohneda and Masayuki Yamamoto -- Lineage selection and transplantation of mouse ES cell-derived neural precursors / Tanja Schmandt, Tamara Glaser, and Oliver Brüstle -- In vitro differentiation of mouse ES cells into pancreatic and hepatic cells / Przemyslaw Blyszczuk, Gabriela Kania, and Anna M. Wobus -- Isolation and characterization of human ES cells / Martin F. Pera ... [et al.] -- Differentiation of human ES cells / Sharon Gerecht-Nir and Joseph Itskovitz-Eldor -- ES cell lines from the cynomolgus monkey (Macaca fascicularis) / Hirofumi Suemori ... [et al.]
    Pages: xxv, 334 p. : ill.
    ISBN: 9780198550006
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  • 5
    Call number: QP501Z:41/61
    Keywords: Radikal / Chemie ; Sauerstoff / Radikal ; Antioxidants ; Umwelt ; Pharmakologie / Nebenwirkung ; Nahrungsmittel / Zusatz
    Notes: Biochemical Society symposium held at the Universitiy of Sussex, December 1994
    Pages: ix, 276 p.
    ISBN: 1-85578-069-0
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    QP501Z:41/61 available
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  • 6
    Keywords: Biochemistry ; Mass spectrometry ; Protein Science ; Mass spectrometry ; Springer eBooks
    Description / Table of Contents: Next Generation Proteomics for Clinical Biomarker Detection using SWATH-MS -- A Combined Chemical Derivatization/Mass Spectrometric Method for the Enhanced Detection and Relative Quantification of Protein Ubiquitination -- Assessment of Ubiquitin Chain Topology by Targeted Mass Spectrometry -- Quantitative Phosphoproteomic using Titanium Dioxide Micro-Columns and Label Free Quantitation -- Isotopic Labeling and Quantitative Proteomics of Acetylation on Histones and Beyond -- Quantitative Analysis of Protein S-Acylation Site Dynamics Using Site-Specific Acyl-Biotin Exchange (ssABE) -- Reducing Complexity? Cysteine Reduction and S-alkylation in Proteomic Workflows: Practical Considerations -- Detection of Unknown Chemical Adduct Modifications on Proteins: From Wet to Dry Laboratory -- Considerations for Identifying Endogenous Protein Complexes from Tissue via Immunoaffinity Purification and Quantitative Mass Spectrometry -- Metaproteomics of Freshwater Microbial Communities -- Peptide-to-Protein Summarization: An Important Step for Accurate Quantification In Label-Based Proteomics -- Experimental Design in Quantitative Proteomics -- Practical Integration of Multi-Run iTRAQ Data -- Quantitative Proteomics Data in the Public Domain: Challenges and Opportunities -- Computational Proteomics with Jupyter and Python -- The Galaxy Platform for Reproducible Affinity Proteomic Mass Spectrometry Data Analysis
    Abstract: New insights into modern medicine and systems biology are enabled by innovative protocols and advanced technologies in mass spectrometry-based proteomics. This volume details new pipelines, workflows, and ways to process data that allow for new frontiers in proteomics to be pushed forward. With applications to biomarker discovery, interactions between proteins, between biological systems, dynamics of post-translational modifications among others, new protocols have been developed and iteratively refined to probe the endless complexity of the proteome in ever greater details. This volume deals with methods for data dependent and data independent mass spectrometry analyses. Valuable, first-hand information is provided from designing experiments, sample preparation and analysis, exploitation of public datasets and carrying out reproducible data pipelines, using modern computational tools such as Galaxy or Jupyter. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mass Spectrometry of Proteins: Methods and Protocols aims to ensure successful results in the further study of this vital field
    Pages: XIII, 264 p. 54 illus., 35 illus. in color. : online resource.
    ISBN: 9781493992324
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  • 7
    Call number: QH301Z:36/56
    Keywords: Nuclear membranes
    Pages: xviii, 344 p. : ill. (some col.)
    ISBN: 0415346452
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  • 8
    Unknown
    New York : Wiley
    Call number: 09-NW:446/1
    Keywords: Nonlinear optics ; Optics ; Physics ; Optique non linéaire
    Notes: "An Interscience publication."
    Pages: xii, 628 p. : ill.
    ISBN: 047117002X
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  • 9
    Keywords: Life sciences ; Proteins ; Enzymology ; Life sciences ; Protein Science ; Enzymology ; Springer eBooks
    Description / Table of Contents: Structural Biology of Nonribosomal Peptide Synthetases -- The Assembly Line Enzymology of Polyketide Biosynthesis -- Measurement of Nonribosomal Peptide Synthetase Adenylation Domain Activity Using a Continuous Hydroxylamine Release Assay -- Affinity Purification Method for the Identification of Nonribosomal Peptide Biosynthetic Enzymes Using a Synthetic Probe for Adenylation Domains -- Colorimetric Detection of the Adenylation Activity in Nonribosomal Peptide Synthetases -- Facile Synthetic Access to Glycopeptide Antibiotic Precursor Peptides for the Investigation of Cytochrome P450 Action in Glycopeptide Antibiotic Biosynthesis -- Reconstitution of Fungal Nonribosomal Peptide Synthetases in Yeast and In Vitro -- The Continuing Development of E. coli as a Heterologous Host for Complex Natural Product Biosynthesis -- Screening for Expressed Nonribosomal Peptide Synthetases and Polyketide Synthases Using LC‒MS/MS-Based Proteomics -- Enhancing Nonribosomal Peptide Biosynthesis in Filamentous Fungi -- In Situ Analysis of Bacterial Lipopeptide Antibiotics by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging -- Secondary Metabolic Pathway-Targeted Metabolomics -- Annotating and Interpreting Linear and Cyclic Peptide Tandem Mass Spectra -- Bioinformatics Tools for the Discovery of New Nonribosomal Peptides -- The Use of ClusterMine360 for the Analysis of Polyketide and Nonribosomal Peptide Biosynthetic Pathways -- Alignment-Free Methods for the Detection and Specificity Prediction of Adenylation Domains -- Characterization of Nonribosomal Peptide Synthetases with NRPSsp
    Abstract: This volume presents an overview of nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) structure and function.℗ It then continues with methods for the analysis of these pathways including conventional enzymological assays, contemporary mass spectrometric analysis techniques, specialized molecular biological approaches applicable to NRPSs and PKSs, and small molecule analysis tools tailored to this very special class of natural products, and concludes by examining bioinformatics tools for the analysis of these enzymes, pathways, and molecules. Written for the highly successful℗ Methods in Molecular Biology℗ series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical,℗ Nonribosomal Peptide and Polyketide Biosynthesis: Methods and Protocols℗ serves as a valuable reference for those experienced in studying NRPS and PKS enzymes, pathways, and natural products as well as a gateway for those just entering the field
    Pages: XI, 281 p. 80 illus., 31 illus. in color. : online resource.
    Edition: 1st ed. 2016.
    ISBN: 9781493933754
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  • 10
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    AMSTERDAM: NORTH-HOLLAND
    Call number: WN620:10/Mag
    Notes: EDINBURGH 1966: 12. -15. 10.
    Pages: 218 S.
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