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  • 1
    ISSN: 1432-0568
    Keywords: Sympathetic System ; Mouse ; Development ; Monoamines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The early development of the sympathetic chain with adjacent ganglia and chromaffin tissue and the appearance of monoamines in these organs was mapped with the Falck-Hillarp fluorescence technique. In the 11 days embryo a few fluorescent cells are found lateral to the aorta in the thoracal region. During the following days the sympathetic chain with segmentally arranged ganglia develops. The cells have a weak to medium fluorescence intensity. A migration of fluorrescent cells ventral to the sympathetic chain can be seen in embryos 12 days old. These migrating cells will later form the prevertebral ganglia and the chromaffin tissue. At the 14 days old stage the adrenal medulla and the paraganglia can be distinguished, while the prevertebral plexa are differentiated in the 15 days old embryo. The chromaffin tissue has a brilliant fluorescence but in the neonatal stages parts of the paraganglia show a weaker fluorescence and though they have their largest extension around the 10th day of postnatal life a brilliant fluorescence can be seen only in a smaller part of the ganglia at that time. The paraganglia are reduced in adult stages.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 133 (1971), S. 305-317 
    ISSN: 1432-0568
    Keywords: Sympathetic Nervous System ; Mouse ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The first visible primordia of the sympathetic chain appear in the anterior thoracic region and run caudally through 8 segments in an embryo of 11 gestation days. At 12 gestation days the trunk reaches from the base of the skull into the sacral region. During the following days the trunk develops into ganglia with interganglionic fibers. At 16 gestation days there is a well developed trunk with a cranial ganglion cervicale superior and a ganglion stellatum in the anterior part of the thoracic region. In the remaining sympathetic chain there are segmentally arranged ganglia but in this common pattern large differences are noticed. At the 13th gestation day the first signs of the adrenal medulla and the splanchnic plexus appear in the form of sympathoblasts ventral to the sympathetic chain. The migration of sympathoblasts into the primordia of the adrenal cortex goes on for 3 days while the migration to the splancnic plexus in the mesenchym ventral and lateral to the aorta goes on at least 2 more days.
    Type of Medium: Electronic Resource
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