Supercritical fluid chromatography
Chemiluminescent nitrogen detection
Flame ionization detection
Analytical Chemistry and Spectroscopy
Wiley InterScience Backfile Collection 1832-2000
Chemistry and Pharmacology
The use of a simultaneous detection system for open-tubular supercritical fluid chromatogrphic separation of aniline isomers, alkyl(C8 to C18)dimethylamines, a dialkylmethylamine mixture, and an extract of a Japanese horseradish power “Wasabi” is demonstrated. A chemiluminescent nitrogen detector (CLND) and a flame ionization detector (FID) were configured at the end of the open tubular column via a zero- to dead-volume tee. The dual detection was achieved with a post-column split at a 1:2.5 ratio for the CLND and FID, respectively. The optimized CLND showed virtually no response to non-nitrogenous components such as benzene, toluene, and methanol which were used as injection solvents in these applications.
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