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Book

Bayesian data analysis / (2004)

Gelman, Andrew

Boca Raton, Fla. : : Chapman & Hall/CRC,

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Call number: B050:269 ; B080:203 ; C060:057

Type of Medium: Book

Pages: xxv, 668 p. : , ill., maps ; , 25 cm.

Edition: 2nd ed.

ISBN: 158488388X (alk. paper)

Series Statement: Texts in statistical science ;

Language: English

Location: Abt

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Book

Bayesian data analysis / (2014)

Gelman, Andrew

Boca Raton, Fla. : : Chapman & Hall/CRC,

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Call number: C060:243 ; W110:014

Type of Medium: Book

Pages: xiv, 667 p. : , ill., maps ; , 25 cm.

Edition: 3rd ed.

ISBN: 978143984095

Series Statement: Texts in statistical science ;

Language: English

Location: Abt

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Electronic Resource

Bayesian probabilistic extensions of a deterministic classification model (2000)

Leenen, Iwin ; Van Mechelen, Iven ; Gelman, Andrew

Springer

Computational statistics 15 (2000), S. 355-371

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ISSN: 1613-9658

Keywords: Keywords: Bayesian Estimation, Boolean Regression, Logical Rule Analysis, Posterior Predictive Checks

Source: Springer Online Journal Archives 1860-2000

Topics: Mathematics

Notes: Summary This paper extends deterministic models for Boolean regression within a Bayesian framework. For a given binary criterion variable Y and a set of k binary predictor variables X 1,...,X k , a Boolean regression model is a conjunctive (or disjunctive) logical combination consisting of a subset S of the X variables, which predicts Y. Formally, Boolean regression models include a specification of a k-dimensional binary indicator vector (θ1,...,θ k ) with θ j = 1 iff X j ∈S. In a probabilistic extension, a parameter π is added which represents the probability of the predicted value ŷ i and the observed value y i differing (for any observation i). Within a Bayesian framework, a posterior distribution of the parameters (θl,...,θ k , π) is looked for. The advantages of such a Bayesian approach include a proper account of the uncertainty in the model estimates and various possibilities for model checking (using posterior predictive checks). We illustrate this method with an example using real data.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s001800000039

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Electronic Resource

Type S error rates for classical and Bayesian single and multiple comparison procedures (2000)

Gelman, Andrew ; Tuerlinckx, Francis

Springer

Computational statistics 15 (2000), S. 373-390

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ISSN: 1613-9658

Keywords: Keywords: Bayesian Inference, Multiple Comparisons, Type 1 Error, Type M Error, Type S Error

Source: Springer Online Journal Archives 1860-2000

Topics: Mathematics

Notes: Summary In classical statistics, the significance of comparisons (e. g., θ1–θ2) is calibrated using the Type 1 error rate, relying on the assuption that the true difference is zero, which makes no sense in many applications. We set up a more relevant framework in which a true comparison can be positive or negative, and, based on the data, you can state “θ1 〉 θ2 with confidence,”“θ2 〉 θ1 with confidence,” or “no claim with confidence.” We focus on the Type S (for sign) error, which occurs when you claim “θ1 〉 θ2 with confidence” when θ2 〉 θ1 (or vice-versa). We compute the Type S error rates for classical and Bayesian confidence statements and find that classical Type S error rates can be extremely high (up to 50%). Bayesian confidence statements are conservative in the sense that claims based on 95% posterior intervals have Type S error rates between 0 and 2.5%. For multiple comparison situations, the conclusions are similar.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s001800000040

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Electronic Resource

Non-hematopoietic allograft cells directly activate CD8 + T cells and trigger acute rejection: An alternative mechanism of allorecognition (2002)

Kreisel, Daniel ; Krupnick, Alexander S. ; Gelman, Andrew E. ; [et al.]

[s.l.] : Nature Publishing Group

Nature medicine 8 (2002), S. 233-239

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ISSN: 1546-170X

Source: Nature Archives 1869 - 2009

Topics: Biology , Medicine

Notes: [Auszug] Despite evidence that human non-hematopoietic cells, such as vascular endothelium, can activate allogeneic T lymphocytes in vitro, the prevailing view has been that hematopoietic antigen-presenting cells are required to trigger alloimmune responses in vivo. Here we report that mouse ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nm0302-233

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Electronic Resource

Surface-Modified Diamond Nanoparticles as Antigen Delivery Vehicles (1995)

Kossovsky, Nir ; Gelman, Andrew ; Hnatyszyn, H. James ; [et al.]

s.l. : American Chemical Society

Bioconjugate chemistry 6 (1995), S. 507-511

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ISSN: 1520-4812

Source: ACS Legacy Archives

Topics: Chemistry and Pharmacology

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1021/bc00035a001

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Electronic Resource

A Probability Model for Golf Putting (2002)

Gelman, Andrew ; Nolan, Deborah

Oxford, UK and Boston, USA : Blackwell Publishing Ltd

Teaching statistics 24 (2002), S. 0

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ISSN: 1467-9639

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Mathematics

Notes: We derive a model, using trigonometry and the Normal distribution, for the probability that a golf putt is successful. We describe a class activity in which we lead the students through the steps of examining the data, considering possible models, constructing a probability model and checking the fit. The model is,of necessity, oversimplified, a point which the class discusses at the end of the demonstration.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/1467-9639.00097

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Electronic Resource

A nondenaturing solid phase pharmaceutical carrier comprised of surface-modified nanocrystalline materials (1990)

Kossovsky, Nir ; Bunshah, Rointan F. ; Gelman, Andrew ; [et al.]

New York, NY [u.a.] : Wiley-Blackwell

Journal of Applied Biomaterials 1 (1990), S. 289-294

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ISSN: 1045-4861

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Medicine , Technology

Notes: Numerous carrier systems have been developed for the controlled delivery of biologically active molecules such as drugs and diagnostic agents. The biophysical interactions between the biologically active molecules and their carriers, however, may denature the former and lead to reduced biological activity. In this study, a model nondenaturing carrier comprised of a nanocrystalline (10-7 m) tin oxide core and a surface-charge-reducing organic bonding layer (GF292) was synthesized. A subsequently bound protein (human transferrin) showed significant retained conformation by immunoelectron microscopy. In the synthesis of targeted drug systems and vaccines, nanocrystalline cores treated with appropriate surface-modifying agents may be suitable carriers.

Additional Material: 5 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jab.770010404

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Electronic Resource

Nanocrystalline epsein-barr virus decoys (1991)

Kossovsky, Nir ; Gelman, Andrew ; Sposler, Edward ; [et al.]

New York, NY [u.a.] : Wiley-Blackwell

Journal of Applied Biomaterials 2 (1991), S. 251-259

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ISSN: 1045-4861

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Medicine , Technology

Notes: A novel biotechnology is introduced by way of the successful synthesis of nanocrystalline Epstein-Barr virus (EBV) decoys having specific in vivo immunogenie activity. Assembled from ultrafine suface modified tin oxide and purified DNA-free isolated EBV envelope proteins, the decoys consisted of 〉150 nm units whose electophoretic mobilities were similar to whole EBV; whose outer coats were strongly immunoreactive with murine monoclonal anti-EBV antibodies; and which elicited immunospecific niutralizing anti-EBV antibodies in the rabbit. The development of this carier techonology for vaccine preparations is suggested.

Additional Material: 7 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jab.770020406

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Surface dependent antigens identified by high binding avidity of serum antibodies in a subpopulation of patients with breast prostheses (1993)

Kossovsky, Nir ; Zeidler, Michelle ; Chun, Grace ; [et al.]

New York, NY [u.a.] : Wiley-Blackwell

Journal of Applied Biomaterials 4 (1993), S. 281-288

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ISSN: 1045-4861

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Medicine , Technology

Notes: There is growing concern in the medical community that silicones, ubiquitous in health care, may exhibit antigenic, immunogenic, and/or adjuvant activity. Sera from women with silicone breast prostheses were assayed by ELISA for humoral immunoreactivity to a variety of common interstitial and cellular components. In decreasing order of frequency, significant IgG avidities were found against silicone surfaces treated with fibronectin-laminin, phospholipids, no treatment, and fibrinogen when compared with sera obtained from healthy, age-matched, nonimplanted women and a population of nonimplanted women with previously diagnosed autoimmune diseases. Moreover, the sera from approximately 15% of the positive responders were found to react to matrix proteins independent of the siloxane polymer. The data show human antibody production to native macromolecules with antibody avidity being related to molecular conformation. Silicone may function as an adjuvant by inducing changes in the conformation of native molecules. © 1993 John Wiley & Sons, Inc.

Additional Material: 4 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jab.770040402

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