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  • 1
    Keywords: Life sciences ; Life sciences ; Life Sciences, general ; Springer eBooks
    Description / Table of Contents: Managing genetic resources -- Building a global plant genetic resources system -- Genomic Approaches to Encouraging the Development of New Cro Varieties through the Granting of Intellectual Property Protection: A Perspective from the Private Sector -- The Use of Molecular Marker Data to Assist in the Determination of Essentially Derived Varieties -- Application of molecular markers in spatial analysis to optimize in situ conservation of plant genetic resources -- Historical and prospective applications of ́€˜quantitative genomicś€™ in utilising germplasm resources -- Platforms and approaches to investigate plant genetic resources -- High-throughput SNP profiling of genetic resources in crop plants using genotyping arrays -- Paleogenomics as a guide for traits improvement -- Non-invasive phenotyping methodologies enable the accurate characterization of growth and performance of shoots and roots -- Association mapping of genetic resources: achievements and future perspectives -- Exploiting barley genetic resources for Genome Wide Association Scans (GWAS -- Production and molecular cytogenetic identification of wheat-alien hybrids and introgression lines -- Radiation hybrids: A valuable tool for genetic, genomic and functional analysis of plant genomes -- FISHIS: a new way in chromosome flow sorting widens the chromosome approach and makes complex genomes more accessible -- Mining genetic resources via Ecotilling -- Genome sequencing and crop domestication -- Next Generation Sequencing and germplasm resources -- Advances in sequencing the barley genome -- The Wheat Black Jack: Advances towards sequencing the 21 chromosomes of the bread wheat genome -- Wheat Domestication: Key to Agricultural Revolutions Past and Future -- Molecular evidence for soybean domestication -- Genomics of origin, domestication and evolution of Phaseolus vulgaris -- Mining allelic diversity -- Advances in Nicotiana Genetic and €œÓmicś€ Resources -- Mining SNPs and linkage analysis in Cynara cardunculus -- Genetic diversity assessment in European Cynara collections -- Analysis and exploitation of cereal genomes with the aid of Brachypodium -- Mining natural variation for maize improvement: Selection on phenotypes and genes -- Breeding forest trees by genomic selection: current progress and the way forward -- Genetic diversity in the grapevine germplasm -- Index
    Abstract: The future of food security will increasingly rely on more extensive exploration and effective exploitation of plant genetic resources. The remarkable progress in plant genomics, sequencing and bioinformatics offers unprecedented opportunities for mining germplasm collections, mapping and cloning loci of interest, identifying novel alleles and deploying them for breeding purposes.℗ Genomics of Plant Genetic Resources presents a state-of-the-art collection of highly interdisciplinary articles describing how genomics improves our capacity to characterize and harness natural and artificially induced variation in order to boost crop productivity and provide consumers with high-quality food. In the past decade, the appreciation of the value of biodiversity has grown rapidly, mainly due to the increased awareness of the pivotal role that plant genetic resources plays for securing the supply of plant-derived products. Meeting the challenges posed by climate change and the needs of the burgeoning population will require a quantum leap in crop productivity, which will only be possible through the integration of genomics-based approaches with extant breeding programs. Additionally, the new selection paradigm ushered in by genomics-assisted breeding will facilitate allele mining in orphan crops and underutilized species, previously less accessible via conventional approaches. The unifying picture that emerges from this book unequivocally shows the pivotal role played by genomics in order to mine germplasm collections, elucidate gene function, identify superior alleles and, ultimately, release improved cultivars. For each of these objectives, the book presents a number of compelling case studies and examples. This unique and timely book℗ is an invaluable reference for educators, researchers, crop specialists, breeders and decision makers interested in managing, mining and harnessing the genetic richness of plant genetic resources.℗
    Pages: XXI, 710 p. 101 illus., 82 illus. in color. : online resource.
    ISBN: 9789400775725
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  • 2
    Keywords: Life sciences ; Agriculture ; Biodiversity ; Botany ; Plant breeding ; Plant Diseases ; Life sciences ; Plant Genetics & Genomics ; Plant Breeding/Biotechnology ; Biodiversity ; Agriculture ; Plant Sciences ; Plant Pathology ; Springer eBooks
    Description / Table of Contents: Harnessing plant genetic diversity for enhancing crop production and its sustainability -- Genetics and genomics of flowering time regulation in sugar beet -- Mining the genus Solanum for increasing disease resistance -- Dissection of potato complex traits by linkage and association genetics as basis for developing molecular diagnostics in breeding programs -- Introgression libraries with wild relatives of crops -- High-throughput phenomics tools for interactions of barley with fungal pathogens -- Genomics of low-temperature tolerance for an increased sustainability of wheat and barley production -- Bridging conventional breeding and genomics for a more sustainable wheat production -- Genetic Dissection of Aluminium Tolerance in the Triticeae -- Maintaining Food Value of Wild Rice (Zizania palustris L.) Using Comparative Genomics -- Genomics-assisted crop improvement for food security -- Genomics-assisted allele mining and its integration into rice breeding -- New insights arising from genomics for enhancing rice resistance against the blast fungus -- Enhancing abiotic stress tolerance in plants by modulating properties of stress responsive transcription factors -- The Borlaug Global Rust Initiative: Reducing the genetic vulnerability of wheat to rust -- Genomes, chromosomes and genes of the wheatgrass genus Thinopyrum: the value of their transfer into wheat for gains in cytogenomic knowledge and sustainable breeding -- Identification and implementation of resistance: Genomics-assisted use of genetic resources for breeding against powdery mildew and Stagonospora nodorum blotch in wheat -- G6nomics-assised crop improvement for nutritional quality -- Breeding for apple (Malus ©— domestica Borkh.) fruit quality traits in the genomics era -- Enhancing nutritional quality in crops via genomics approaches -- N. Genomics of mineral nutrient biofortification: calcium, iron and zinc -- Optimising the content and composition of dietary fibre in wheat grain for end-use quality -- TILLING for improved starch composition in wheat -- Molecular Breeding for Quality Protein Maize (QPM. Index. ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗
    Abstract: The future of food security will increasingly rely on more extensive exploration and effective exploitation of plant genetic resources. The remarkable progress in plant genomics, sequencing and bioinformatics offers unprecedented opportunities for mining germplasm collections, mapping and cloning loci of interest, identifying novel alleles and deploying them for breeding purposes.℗ Genomics of Plant Genetic Resources presents a state-of-the-art collection of highly interdisciplinary articles describing how genomics improves our capacity to characterize and harness natural and artificially induced variation in order to boost crop productivity and provide consumers with high-quality food. In the past decade, the appreciation of the value of biodiversity has grown rapidly, mainly due to the increased awareness of the pivotal role that plant genetic resources plays for securing the supply of plant-derived products. Meeting the challenges posed by climate change and the needs of the burgeoning population will require a quantum leap in crop productivity, which will only be possible through the integration of genomics-based approaches with extant breeding programs. Additionally, the new selection paradigm ushered in by genomics-assisted breeding will facilitate allele mining in orphan crops and underutilized species, previously less accessible via conventional approaches. The unifying picture that emerges from this book unequivocally shows the pivotal role played by genomics in order to mine germplasm collections, elucidate gene function, identify superior alleles and, ultimately, release improved cultivars. For each of these objectives, the book presents a number of compelling case studies and examples. This unique and timely book℗ is an invaluable reference for educators, researchers, crop specialists, breeders and decision makers interested in managing, mining and harnessing the genetic richness of plant genetic resources.℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗
    Pages: XIX, 515 p. 60 illus. in color. : online resource.
    ISBN: 9789400775756
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  • 3
    Abstract: CXCR4 is a chemokine receptor that is overexpressed in various human cancers and is involved in tumor metastasis. The aim of this proof-of-concept study was to evaluate a novel CXCR4-targeted PET probe in patients with solid cancers with reported in vitro evidence of CXCR4 overexpression and to estimate its potential diagnostic value. METHODS: Twenty-one patients with histologically proven pancreatic cancer, laryngeal cancer, non-small cell lung cancer, prostate cancer, melanoma, breast cancer, hepatocellular carcinoma, glioblastoma, sarcoma, or cancer of unknown primary underwent PET imaging using the novel CXCR4 nuclear probe (68)Ga-pentixafor. The SUVmax of the liver, spleen, and bone marrow was measured to determine physiologic tracer distribution. For evaluation of tracer accumulation in solid cancers, SUVmax and tumor-to-background (T/B) ratios were determined in a total of 43 malignant lesions, including 8 primary tumors, 3 locally recurrent tumors, and 32 metastases. When available, the SUVmax of malignant lesions was compared with the corresponding SUVmax measured in routine (18)F-FDG PET. RESULTS: Moderate tracer accumulation was detectable in the liver, bone marrow, and spleen, with a mean SUVmax of 3.1, 3.7, and 5.6, respectively. By visual interpretation criteria, 9 of 11 primary and locally recurrent tumors were detectable, exhibiting a mean SUVmax of 4.7 (range, 2.1-10.9) and a mean T/B ratio of 2.9. Twenty of 32 evaluated metastases were visually detectable (mean SUVmax, 4.5 [range, 3.2-13.8]; mean T/B ratio, 2.8). The highest signal was detected in a patient with non-small cell lung cancer (SUVmax, 10.9; T/B ratio, 8.4) and a patient with cancer of unknown primary (SUVmax, 13.8; T/B ratio, 8.1). Compared with (18)F-FDG PET, which was additionally performed in 10 patients, (68)Ga-pentixafor PET had a lower SUVmax in all measured malignant lesions. CONCLUSION: On the basis of these first observations in a small and heterogeneous patient cohort, the in vitro CXCR4 expression profile of solid cancers and metastases described in the previous literature does not seem to sufficiently depict the in vivo distribution revealed by CXCR4-targeted PET. Moreover, the detectability of solid cancers seems to be generally lower for (68)Ga-pentixafor than for (18)F-FDG PET.
    Type of Publication: Journal article published
    PubMed ID: 26769866
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  • 4
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  49. Jahrestagung der Österreichischen Gesellschaft für Plastische, Ästhetische und Rekonstruktive Chirurgie (ÖGPÄRC), 42. Jahrestagung der Deutschen Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC), 16. Jahrestagung der Vereinigung der Deutschen Ästhetisch-Plastischen Chirurgen (VDÄPC); 20110929-20111001; Innsbruck; DOC11dgpraecV75 /20110927/
    Publication Date: 2011-09-27
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 5
    ISSN: 0584-8539
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Spectrochimica Acta 19 (1963), S. 2113-2127 
    ISSN: 0371-1951
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    ISSN: 0378-4371
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica B: Physics of Condensed Matter 169 (1991), S. 209-216 
    ISSN: 0921-4526
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 0960-8974
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Geosciences , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0965-1748
    Keywords: Fertilization ; Monoclonal antibodies ; Proteoglycans ; Sperm
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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