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  • 1
    ISSN: 1432-2307
    Keywords: Fibrous histiocytomas ; Structural patterns ; Reconstruction of storiform structures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A storiform pattern is an important structural feature of fibrous histiocytoma (FH). In this analysis reconstructions of histological patterns were carried out from drawings. Highly cellular FH with only a suggestion of storiform pattern and small star-formations were seen, there were other lesions with more pronounced fiber formation which showed more distinct and larger storiform stars. These structures can frequently be followed for only 3 sections of 5 micron thickness. In contrast to leiomyomas or meningioma, no regular or consistent orientation of these structures with respect to vessels is evident. Storiform structures apparently develop at the periphery of adjacent proliferating cells groups. They show a typical and diagnostically significant histological pattern, which was found to some degree in all FH examined.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2307
    Keywords: Benign and malignant fibrous histiocytomas ; Storiform pattern ; Incidence ; Histological structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A starlike arrangement of cells and fibers, the “storiform pattern”, was found to be a typical, but not obligatory, histological feature of benign and malignant fibrous histiocytomas. In 155 benign fibrous histiocytomas storiform structures were missing in 29 cases, chiefly of the fibroblastic type comparable with classical “dermatofibroma”. 12 of 70 malignant fibrous histiocytomas did not reveal storiform structures, especially the cellular pleomorphic variant, i.e. the classical pleomorphic sarcoma. Storiform structures were either small and highly cellular with few fibers (collagen type III), or larger, less cellular, but with abundant fibers (collagen type I). There was no sharp demarcation between these two extremes, but many transitional structures or patterns were seen. The histiocytic nature of the cells was demonstrated in both variants of storiform structures by immunhistochemical methods on paraffin embedded material. Alpha1-anti-chymotrypsin was especially valuable in this respect.
    Type of Medium: Electronic Resource
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