Cyclopropanes, nucleophilic substitution at
Springer Online Journal Archives 1860-2000
Chemistry and Pharmacology
Abstract Reaction of HexahydroazepinobicycloalkylMeldrum's acid7 Ba-7 Bd or PiperidinocyclopropylMeldrum's acid7 Ce withMeldrum's acid (1) generates cyclopropanes possessing two isopropylidene malonate moieties. In the solid state the bicyclic derivatives were found to be dienolic compounds11 a-11 d, whereas the monocyclic system has the tetracarbonyl structure10e. 7a-7d, the starting materials for the synthesis of11 a-11 d, were obtained from1 and O,N-acetal4B or aminal6B.
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