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  • 1
    ISSN: 1432-1084
    Keywords: Key words: Aneurysm ; Abdominal ; Pulmonary ; Therapy ; Immunosuppression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. We studied the value of contrast-enhanced CT in the detection of aneurysms in immunocompromised patients suffering from inflammatory diseases eventually complicated by hemorrhage. Contrast-enhanced spiral CT was applied in three patients with immunocompromise due to chemotherapy, alcohol abuse or HIV. They suffered from invasive aspergillosis, chronic pancreatitis with pseudocyst formation, and acute pancreatitis together with HIV-associated lymphadenopathy. Complicating hemorrhage was present in two cases. Contrast-enhanced CT showed aneurysms complicating the underlying inflammatory disease in all three cases. The feeding vessels were identified and the patients with signs of bleeding were subsequently referred for angiography and embolization. Contrast-enhanced spiral CT is suited to detect aneurysms in immunocompromised patients suffering from inflammatory disease. It is recommended in these patients prior to angiography and intervention.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: Key words: Helical CT ; Dynamic MR imaging ; Kidney ; Inflammation ; AIDS ; Aspergillosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Renal insufficiency or allergic reactions for X-ray contrast agents are frequent limitations in immunocompromised hosts such as neutropenic or AIDS patients. Due to a better tolerance of contrast agents in MRI, this technique is well suited for investigation of parenchymal organs. We demonstrate an allergic AIDS patient who presented with fever and flank pain. At sonography, anechoic renal lesions were supposed to be non-complicated cysts; however, on T2-weighted MRI, the center was of high signal. Dynamic contrast-enhanced MRI of the kidneys demonstrated an enhancing rim with ill-defined margins. The lesions were supposed to be multiple bilateral abscesses. Due to the multiple dynamic contrast series, a delayed enhancement of renal parenchyma was detectable adjacent to the lesion. This was suggested as accompanying local pyelonephritis and an infectious etiology became more reliable. Aspergillus fumigatus was identified by CT-guided biopsy as the underlying microorganism. The MR appearance of this manifestation has not been described previously.
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  • 3
    ISSN: 1433-0415
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Die moderne Tumortherapie ist durch die zunehmende Zahl von Hochdosisprotokollen immer häufiger mit einer lang andauernden Neutropenie und der daraus resultierenden Immunabwehrschäche verbunden [11, 16, 24]. Die Infektionshäufigkeit liegt bei einer Neutropeniedauer von mehr als 8–10 Tagen bei über 85% [23]. Bei etwa der Hälfte der Patienten kommt es nach empirischer Therapie und initialer Entfieberung im weiteren Verlauf erneut zu einem Temperaturanstieg und damit wiederum zu einem Infektionsverdacht [16, 38, 47]. Dabei sind neben disseminierten Infektionen hauptsächlich Lunge, Nasennebenhöhlen, Darm, Leber, Milz, Gehirn und Nieren betroffen [23, 24].
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  • 4
    ISSN: 1432-2102
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Die moderne Tumortherapie ist durch die zunehmende Zahl von Hochdosisprotokollen immer häufiger mit einer lang andauernden Neutropenie und der daraus resultierenden Immunabwehrschwäche verbunden [11, 16, 24]. Die Infektionshäufigkeit liegt bei einer Neutropeniedauer von mehr als 8–10 Tagen bei über 85% [23]. Bei etwa der Hälfte der Patienten kommt es nach empirischer Therapie und initialer Entfieberung im weiteren Verlauf erneut zu einem Temperaturanstieg und damit wiederum zu einem Infektionsverdacht [16, 38, 47]. Dabei sind neben disseminierten Infektionen hauptsächlich Lunge, Nasennebenhöhlen, Darm, Leber, Milz, Gehirn und Nieren betroffen [23, 24].
    Type of Medium: Electronic Resource
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