Mouth floor carcinoma
Springer Online Journal Archives 1860-2000
Abstract From 1967 through 1984 a total of 151 patients with squamous cell carcinoma of the floor of the mouth were treated by radiation therapy at the Department of Radiology, Osaka University Hospital. For 136 determinate patients, 5-year local control rate of primary lesion was 72%. According to T stage, local control rate was 86% for T1 lesions, 71% for T2, 70% for T3, and 58% for T4. A majority of T1 or early T2 lesions were curable by brachytherapy alone or external irradiation combined with bleomycin or peplomycin. For advanced T2 or T3 lesions, external irradiation combined with bleomycin or peplomycin and followed by brachytherapy was applied. Surgery was reserved for relatively radioresistant tumor or for neck dissection and/or salvage of disease recurred at the primay site or in the neck. Overall five-and ten-year survival rates were 55% and 49%, respectively. According to stage, five-year survival rate was 95% for Stage I (20 patients), 55% for Stage II (48), 45% for Stage III (51), and 46% for Stage IV (32), included the results of salvage surgery.
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