Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-2307
    Keywords: Splenic grafts ; Morphology ; Histoquantitation ; Lymphocytes ; Splenectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Splenic grafts autotransplanted at splenectomy into the omentum of 23 Porton strain rats were compared with spleens from 10 sham-operated controls. Six months after transplantation, the grafts weighed between 81 to 545 mg (median 166 mg) compared to control spleens which weighed 775 to 1,250 mg (median 995 g). Histoquantitation of the grafts revealed marked reduction of the splenic white pulp when compared to control spleens. Morphological examination showed not only a reduction of lymphocytes but also a striking architectural abnormality in all grafts. In 2 of the transplants, no lymphoid aggregates were observed; small subcapsular collections were present in 7, while in 8, isolated perivascular aggregates of lymphocytes with poorly formed marginal zones were observed. Only 6 transplanted spleens showed linkage of adjacent lymphoid aggregates but the number and size of these aggregates were clearly less than normal. These findings indicate that autotransplanted splenic tissue in rats does not regain histological normality. The implications of these observations for autotransplantation in splenectomized patients are discussed.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1432-2218
    Keywords: Hypothermia ; Laparoscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Hypothermia is a common postsurgical problem, yet information documenting the impact of laparoscopy on perioperative heat balance is scarce. This paper quantifies the changes in core temperature over a 3-h period of high-flow CO2 insufflation in a randomized, controlled trial of six pigs. Each animal was anesthetized and studied on three occasions under standardized conditions, acting as its own control via insufflation with no gas compared with insufflation by cold gas and warmed gas. Insufflation of CO2 gas at high-flow rates over a prolonged period of time results in a significant fall in core temperature. The provision of warmed rather than cold insufflated gas confers no protection against changes in core temperature during laparoscopic surgery due to the small amount of heat required to warm the gas to body temperature. A much greater effect is the latent heat required to saturate the insufflated gas. Most of the hypothermic effect is due to this, and could be minimized by humidifying the flow.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1432-2218
    Keywords: Laparoscopy ; Surgery ; Fundoplication ; Esophagitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract From September 1991 to January 1995 we performed 230 Nissen fundoplications by a laparoscopic technique. Whilst a loose 360° fundoplication secured by 3 or 4 sutures was performed in all instances, there was variation between surgeons regarding the performance of hiatal repair and division of short gastric vessels; 207 operations were completed laparoscopically and 23 were converted to an open operation when a satisfactory wrap could not be achieved. Operating time ranged from 30 to 260 min (median 95) and the median postoperative stay was 3 days (1–19). Twenty-three patients (10%) underwent a subsequent operation (14 within 3 months of the original surgery), 2 for recurrent reflux, 10 for para-esophageal herniation, 2 for a misplaced fundoplication resulting in gastric obstruction, 7 for persistent dysphagia (4 due to stenosis of the esophageal hiatus), 1 for bleeding, and 1 for mesenteric thrombosis. (This patient died.) Five other patients were readmitted to hospital subsequent to their discharge—four because of pulmonary emboli and one because of gastric obstruction. Some 226 patients (98%) are free of reflux symptoms with follow-up ranging up to 40 months (median 16). Absence of reflux and the integrity of the fundoplication has been confirmed by postoperative esophageal manometry and pH monitoring in 90 patients, and by barium meal in 126. Postoperative recovery has been quick and wound-related morbidity minimal. Although the rate of surgical revision was significant in this series, the likelihood of complications or further surgery, as well as incidence of conversion to open surgery, decreased in the second half of the experience. Strategies developed to improve the outcome now include routine posterior closure of the hiatus, early postoperative barium-meal examination, and minimization of diathermy dissection. A loose fundoplication is always constructed over a large bougie. The need for division of the short gastric vessels in laparoscopic fundoplication remains controversial and awaits the outcome of a randomized trial.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Two methods were used for altering blood pressure in conscious rabbits by up to ± 30 mmHg from the resting level in order to characterize the barorecep-tor-heart rate reflex. These were to inflate descending aortic or inferior vena caval cuffs, or to give brief intravenous infusions of phenylephrine or glycerol trinitrate. The relation of change in blood pressure to change in heart interval was examined, both during the initial ‘ramp’ changes of these variables and when they had reached a ‘steady-state'.2. Both methods allowed the construction of'steady-state’ sigmoid stimulus-response curves whose parameters were reproducible within animals, and which were attended by a relatively small variance between animals. The inflatable-cuff method gave a higher average value for maximum gain than the vasoactive drug method (10.0 v 5-4 ms/mmHg) and a narrower pressure range between the threshold and saturation points of the response, but values for the other parameters were similar. Corresponding parameters obtained by the two methods correlated closely.3. After denervating all arterial baroreceptors except one carotid sinus, ‘steady-state’ maximum gain by cuff-inflation was reduced to 3.1 ms/mmHg, and to 2-6 ms/mmHg by the vasoactive drug method. The heart interval range between upper and lower plateau levels was reduced, but the pressure range between threshold and saturation points was widened, with both methods.4. During the initial ‘ramp’ changes of blood pressure the sensitivity of the reflex was described by the slope of the linear regression of heart interval on ‘mean blood pressure. The slopes obtained by aortic cuff inflation, and by infusion of either vasoactive drug, correlated positively with ‘steady-state’ maximum gain. However, the reproducibility of the ‘ramp’ method was inferior to that of the ‘steady-state’ method with respect to reflex sensitivity, and other parameters of the stimulus-response relation cannot be estimated.5. Complete baroreceptor denervation virtually eliminated heart rate changes over the range of blood pressures usually employed. However, when blood pressure was increased by more than 40 mmHg a profound reflex bradycardia and hypopnoea were then evoked.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Experimental Cell Research 106 (1977), S. 380-386 
    ISSN: 0014-4827
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We report the first full analysis of collisionally induced atomic alignment and orientation for a molecular collision process. In an experiment with crossed supersonic beams of N0 and laser excited Na(32 P 3/2) we have studied the dependence of angular and energy resolved differential quenching cross sections as a function of the linear and circular polarization of the exciting laser light. The anisotropies observed in the linear polarization data range up to 2∶1 when corrected for electron and nuclear spin relaxation. The maximum effect is found at small scattering angles and intermediate energy transfer where the cross section is also largest. The atomic alignment angle most favourable for quenching relates to the scattering angle and can be understood in a model picture in such a way that the (NaN2)* molecular system is formed at internuclear distances as low asR=10a 0. The circular asymmetry is small but with significant structure and is attributed to interaction on different potential surfaces atR〉10a 0. Full analysis of the four measurable parameter is given in terms of the density matrix in a frame withz-axis perpendicular to collision plane which allows a clear understanding of the properties of atomic reflection symmetry and coherence of the scattering process.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1615-6102
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The ultrastructural changes which occur during the foliar abscission ofImpatiens sultani Hook. andColeus blumei Benth. have been described. In both cases fracture of the separation zone results from a modification of the wall and cleavage along the line of the middle lamella. This process starts at the corners of the cells and in regions rich in plasmodesmata. During the period of wall breakdown, cellular integrity is maintained and the membrane degradation described by others was not observed. Plasmolysis studies confirmed that the separation zone cells retained their selective permeability characteristics until well after wall fracture. Quantitative data are presented to show that there is an increase in the frequency of rough endoplasmic reticulum, dictyosomes and dictyosome vesicles during the period when wall-hydrolyzing enzyme secretion is occurring. These changes are interpreted as reflecting an increase in demand for the secretory machinery of the endomembrane system. The possible involvement of plasmodesmata in this process is also discussed.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...