Springer Online Journal Archives 1860-2000
Chemistry and Pharmacology
Conclusion Estimation of aprotinin in plasma with the described amidolytic assay can be achieved within 70–80min and is, therefore, convenient as a bedside-control of high dose proteinase inhibitor therapy. Moreover, an ELISA for aprotinin developed simultaneously (Müller-Esterl et al. this issue) allows the detection of up to 0.2KIU/ml within 4h and is suitable, therefore, for special purposes, e.g. retrospective studies and low dose inhibitor therapy.
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