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  • 1
    Keywords: Human Genetics ; Epidemiology ; Statistical methods ; Medicine ; Human Genetics ; Epidemiology ; Biostatistics ; Health Promotion and Disease Prevention ; Molecular Medicine ; Springer eBooks
    Description / Table of Contents: Preface -- Dedication -- Contents -- Introduction To Human Genetic Epidemiology -- Data Analysis Using R Programming -- Applied Statistics For Human Genetics Using R -- Applied Human Genetic Epidemiology -- Human Genetic Epidemiology Using R -- References -- Subject Index
    Abstract: This book illustrates how biostatistics may numerically summaries human genetic R, and may be used successfully to solve problems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems. It begins by introducing all the necessary probabilistic and statistical foundations, before moving on to topics related human genetic epidemiology, with R codes illustrations for various examples. This clear and concise book covers human genetic epidemiology, using R in data analysis, including multivariate data analysis. It examines probabilistic and statistical theories for modeling human genetic epidemiology – leading the readers through an effective epidemiologic model, from simple to advanced levels. Classical mathematical, probabilistic, and statistical theory are thoroughly discussed and presented. This book also presents R as a calculator and using R in data analysis. Additionally, it covers Advanced Human Genetic Data Concepts, the Study of Human Genetic Variation, Manhattan Plots, as well as the Procedures for Multiple Comparison. Numerous Worked Examples are provided for illustrations of concepts and real-life applications. Biostatistics for Human Genetic Epidemiology is an ideal reference for professionals and students in Medicine (particularly in Preventive Medicine and Public Health Medical Practices), as well as in Genetics, Epidemiology, and Biostatistics
    Pages: XVI, 355 p. 85 illus., 44 illus. in color. : online resource.
    ISBN: 9783319937915
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  • 2
    Call number: F065:4
    Keywords: Polymerase Chain Reaction / methods
    Description / Table of Contents: Introduction to the polymerase chain reaction / Y.M. Dennis Lo and K.C. Allen Chan -- Setting up a polymerase chain reaction laboratory / Y.M. Dennis Lo and K.C. Allen Chan -- Real time polymerase chain reaction and melting curve analysis / Robert J. Pryor and Carl T. Wittwer -- Qualitative and quantitative polymerase chain reaction-based methods for DNA methylation analyses / Ivy H.N. Wong -- In-cell polymerase chain reaction: strategy and diagnostic applications / T. Vauvert Hviid -- Qualitative and quantitative DNA and RNA analysis by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry / Chunming Ding -- Analysis of polymerase chain reaction products by denaturing high performance liquid chromatography / Ching-Wan Lam -- Use of real time polymerase chain reaction for the detection of fetal aneuploidies / Bernhard Zimmermann ... [et al.] -- Noninvasive prenatal diagnosis by analysis of fetal DNA in maternal plasma / Rossa W. K. Chiu and Y. M. Dennis Lo --
    Pages: x, 200 p. : ill.
    Edition: 2nd ed.
    ISBN: 1588293483
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    F065:4 departmental collection or stack – please contact the library
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  • 3
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    Totowa, N.J. : Humana Press
    Associated volumes
    Call number: QH506:60/248
    Keywords: Antibodies / therapeutic use ; Antibodies / genetics ; Protein Engineering / methods
    Pages: xiv, 561 p. : ill.
    ISBN: 1588290921
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    QH506:60/248 available
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  • 4
    Keywords: Otorhinolaryngology ; Neurosciences ; Otorhinolaryngology ; Neurosciences ; Springer eBooks
    Description / Table of Contents: Preface -- Visual Influence on Auditory Perception -- Cue Combination Within a Bayesian Framework -- Toward a Model of Auditory-Visual Speech Intelligibility -- An Object-Based Interpretation of Audiovisual Processing -- Hearing in a “Moving” Visual World: Coordinate Transformations Along the Auditory Pathway -- Multisensory Processing in the Auditory Cortex -- Audiovisual Integration in the Primate Prefrontal Cortex -- Using Multisensory Integration to Understand the Human Auditory Cortex -- Combining Voice and Face Content in the Primate Temporal Lobe -- Neural Network Dynamics and Audiovisual Integration -- Cross-Modal Learning in the Auditory System -- Multisensory Processing Differences in Individuals with Autism Spectrum Disorder
    Abstract: Auditory behavior, perception, and cognition are all shaped by information from other sensory systems. This volume examines this multi-sensory view of auditory function at levels of analysis ranging from the single neuron to neuroimaging in human clinical populations. Visual Influence on Auditory Perception Adrian K.C. Lee and Mark T. Wallace Cue Combination within a Bayesian Framework David Alais and David Burr Toward a Model of Auditory-Visual Speech Intelligibility Ken W. Grant and Joshua G. W. Bernstein An Object-based Interpretation of Audiovisual Processing Adrian K.C. Lee, Ross K. Maddox, and Jennifer K. Bizley Hearing in a “Moving” Visual World: Coordinate Transformations Along the Auditory Pathway Shawn M. Willett, Jennifer M. Groh, Ross K. Maddox Multisensory Processing in the Auditory Cortex Andrew J. King, Amy Hammond-Kenny, Fernando R. Nodal Audiovisual Integration in the Primate Prefrontal Cortex Bethany Plakke and Lizabeth M. Romanski Using Multisensory Integration to Understand Human Auditory Cortex Michael S. Beauchamp Combining Voice and Face Content in the Primate Temporal Lobe Catherine Perrodin and Christopher I. Petkov Neural Network Dynamics and Audiovisual Integration Julian Keil and Daniel Senkowski Cross-Modal Learning in the Auditory System Patrick Bruns and Brigitte Röder Multisensory Processing Differences in Individuals with Autism Spectrum Disorder Sarah H. Baum Miller, Mark T. Wallace Adrian K.C. Lee is Associate Professor in the Department of Speech & Hearing Sciences and the Institute for Learning and Brain Sciences at the University of Washington, Seattle Mark T. Wallace is the Louise B McGavock Endowed Chair and Professor in the Departments of Hearing and Speech Sciences, Psychiatry, Psychology and Director of the Vanderbilt Brain Institute at Vanderbilt University, Nashville Allison B. Coffin is Associate Professor in the Department of Integrative Physiology and Neuroscience at Washington State University, Vancouver, WA Arthur N. Popper is Professor Emeritus and research professor in the Department of Biology at the University of Maryland, College Park Richard R. Fay is Distinguished Research Professor of Psychology at Loyola University, Chicago
    Pages: XVI, 272 p. 70 illus., 49 illus. in color. : online resource.
    ISBN: 9783030104610
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  • 5
    Call number: QZ50:16
    Keywords: Medical genetics / Congresses ; Chemical mutagenesis / Congresses ; Mutagenicity testing / Congresses ; Health risk assessment / Congresses ; Mutagens / Adverse effects ; Mutation / congresses ; Genes / Drug effects ; Environmental Exposure / congresses
    Notes: Sponsored by the Dept. of National Health and Welfare, Canada, and others.
    Pages: xxiv, 364 p. : ill.
    ISBN: 0444803521
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    QZ50:16 available
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  • 6
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    Oxford [Oxfordshire] : IRL Press
    Call number: 08-BIOCH
    Keywords: High performance liquid chromatography ; Biochemistry
    Pages: xviii, 333 p. : ill.
    ISBN: 0947946772
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    08-BIOCH departmental collection or stack – please contact the library
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  • 7
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    Chichester, West Sussex : Wiley
    Call number: QP551:268
    Keywords: Proteins / analysis ; Nuclear magnetic resonance spectroscopy ; SCIENCE / Spectroscopy & Spectrum Analysis
    Abstract: "Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful technique in structural biology for obtaining high resolution 3-D structures of proteins, second only, and complementary to X-ray crystallography. Molecules are studied in solution, where conditions are closer to what is found in the cell. It is the primary technique used to obtain information on intrinsically disordered (unfolded) proteins, since these proteins will not crystallize easily.The aim of this book is to provide the newcomer to NMR techniques with practical guidance on how to choose the right experiment, how to carry out the experiment, and how to analyse the resulting spectra. Those who are familiar with the chemical applications of NMR will also find it helpful in describing the special requirements of proteins"--
    Pages: xiv, 351 p., [10] p. of col. plates : ill.
    ISBN: 9780470721933
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    QP551:268 available
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  • 8
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    Berlin, Heidelberg : Springer
    Keywords: Life sciences ; Biochemistry ; Bioinformatics ; Microscopy ; Engineering ; Life sciences ; Biochemistry, general ; Biophysics and Biological Physics ; Protein Science ; Biological Microscopy ; Bioinformatics ; Nanotechnology and Microengineering ; Springer eBooks
    Description / Table of Contents: 〈p〉Proteins -- DNA and RNA -- Carbohydrates -- Macromolecular complexes, Mechanoenzymes -- Membrane biophysics -- Electron transfer -- Ion Channels -- Receptors -- Transporters -- Biomaterials & Biosensors -- Diffraction methods -- NMR -- EPR -- Optical spectroscopy -- X-ray spectroscopy -- Single molecule methods -- Computational Biophysics -- Thermodynamics -- Kinetics -- Mass spectrometry -- Molecular shape & hydrodynamics -- Electron microscopy -- Live cell & in vivo imaging -- Cell biophysics.〈/p〉
    Abstract: 〈p〉The Encyclopedia of Biophysics is envisioned both as an easily accessible source of information and as an introductory guide to the scientific literature. It includes entries describing both Techniques and Systems.℗ 〈br〉In the Techniques entries, each of the wide range of methods which fall under the heading of Biophysics are explained in detail, together with the value and the limitations of the information each provides. Techniques covered range from diffraction (X-ray, electron and neutron) through a wide range of spectroscopic methods (X-ray, optical, EPR, NMR) to imaging (from electron microscopy to live cell imaging and MRI), as well as computational and simulation approaches.〈br〉In the Systems entries, biophysical approaches to specific biological systems or problems ́€“ from protein and nucleic acid structure to membranes, ion channels and receptors ́€“ are described. These sections, which place emphasis on the integration of the different techniques, therefore provide an inroad into Biophysics from a biological more than from a technique-oriented physical/chemical perspective.℗ 〈br〉Thus the Encyclopedia is intended to provide a resource both for biophysicists interested in methods beyond those used in their immediate sub-discipline and for those readers who are approaching biophysics from either a physical or biological background.℗ ℗ 〈/p〉〈p〉
    ISBN: 9783642167126
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  • 9
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims : To study the prevalence, clinical characteristics and long-term outcome of oesophagitis in Chinese patients.Methods : Clinical and endoscopic data were collected prospectively from consecutive patients who underwent upper endoscopy between 1997 and 2001. Patients with endoscopic oesophagitis were graded according to the Los Angeles system and analysed according to their clinical presentation, endoscopic details, Helicobacter pylori status, non-steroidal anti-inflammatory drug history, co-morbidity and mortality.Results : A total of 22 628 upper endoscopies were performed in 16 606 patients. Of these, 631 (3.8%) had endoscopic oesophagitis, 14 had benign oesophageal stricture (0.08%) and 10 had Barrett's oesophagus (0.06%). Most patients (94%) had either Los Angeles grade A or grade B oesophagitis. Patients who died during follow-up had a significantly higher incidence of co-morbid illness (100% vs. 63%, P 〈 0.001). By Cox regression analysis, the presence of gastrointestinal bleeding (P = 0.008), advanced age (P = 0.004) and the use of Ryle's tube (P = 0.043) were identified to be independent factors associated with mortality.Conclusions : Complicated gastro-oesophageal reflux disease is uncommon in the Asian population. Advanced age, use of Ryle's tube and the presence of gastrointestinal bleeding are associated with a poor long-term outcome, which is a reflection of the severe underlying co-morbidity.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0942-0940
    Keywords: Keywords: Intramedullary spinal cord ganglioglioma; outcome; gross total resection.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary ¶ We report five cases of ganglioglioma in various locations. The tumours were removed with gross total resection in most cases without any further neurological deterioration. Without any additional treatment, no evidence of recurrence or regrowth of tumours was observed in the mean follow-up period of 4.1 years. We suggest that intramedullary spinal cord gangliogliomas be resected totally due to the high risk of recurrence and regrowth rate of the tumours with subtotal resection in the long term considering especially that these tumours affect predominantly young patients.
    Type of Medium: Electronic Resource
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