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  • 1
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR); 20160831-20160903; Frankfurt am Main; DOCER.27 /20160829/
    Publication Date: 2016-08-29
    Keywords: Fokal adhesion kinase ; Baricitinib ; Tofacitinib ; Rheumatoid arthritis ; ddc: 610
    Language: English
    Type: conferenceObject
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  • 2
    ISSN: 1573-2622
    Keywords: Anterior uveitis ; HLA-B27 ; urogenital infection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Acute anterior uveitis (AAU) may be associated with systemic infectious or inflammatory disease. We examined 92 patients with the first attack of acute anterior uveitis; all patients were free of any extraocular symptoms. A thorough clinical examination did not reveal any systemic underlying disease. In the course of microbiological examination, however, a high incidence of asymptomatic infection of the urethra and/or cervix with ureaplasma urealyticum, chlamydia trachomatis and mycoplasma hominis was found. Infections with ureaplasma were significantly more frequent in patients with AAU when compared with a sex- and age-matched control group. There was no statistically valid association of these infections with the HLA-B27 phenotype in the patients. The higher rate of urogenital infections in patients with AAU may reflect a higher rate of sexual promiscuity. Transmission of infectious agents seems to be one possible factor in the pathogenesis of AAU.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Rheumatoide Arthritis ; Lungenveränderungen ; Thoraxröntgen ; Computertomographie ; Thorax ; Key words Rheumatoid arthritis ; Pulmonary alterations ; Radiography ; chest ; Computed tomography ; Thorax
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Pulmonary complications caused by rheumatoid arthritis are a clinically relevant aspect of this chronic arthropathy. Those complications can involve all parts of the thorax, including the lung parenchyma, the pleura, and the thoracic cage. The most common complications are necrobiotic nodules, pleural abnormalities, Caplan's syndrome, parenchymal fibrosis, bronchiolitis obliterans, and iatrogenic damage of lung the parenchyma. This article reviews pulmonary abnormalities induced by rheumatoid arthritis and their clinical and radiological findings. In addition, the role of different imaging modalities in the diagnostic work-up of pulmonary complications caused by rheumatoid arthritis is discussed.
    Notes: Zusammenfassung Lungenveränderungen im Rahmen der rheumatoiden Arthritis stellen einen klinisch bedeutsamen Aspekt dieser in Schüben verlaufenden chronischen Arthropathie dar. Die mit dem Bestehen einer rheumatoiden Arthritis verbundenen pulmonalen Veränderungen können alle anatomischen Teile des Lungenparenchyms, die Pleura sowie Teile des knöchernen Thorax betreffen. Die wichtigsten thorakalen Veränderungen im Rahmen der rheumatoiden Arthritis sind die nekrobiotischen Rheumaknoten, pleurale Veränderungen, das Caplan-Syndrom, die Lungenfibrose, die Bronchiolitis obliterans und medikamentös induzierte Lungenveränderungen. Der vorliegende Artikel beschreibt das Spektrum der Lungenveränderungen, die im Rahmen der rheumatoiden Arthritis vorkommen. Hierbei werden die klinischen und radiologischen Charakteristika dieser Veränderungen vorgestellt. Die Bedeutung der verschiedenen bildgebenden Methoden im diagnostischen Algorithmus wird diskutiert.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 197 (1962), S. 231-261 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0428
    Keywords: Keywords Diabetic nephropathy ; risk factors ; ACE polymorphism ; glycaemic control ; hypertension.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Diabetic nephropathy represents a major complication in patients with insulin-dependent diabetes mellitus (IDDM). Intervention trials using angiotensin-converting enzyme (ACE) inhibitors have pointed towards the important pathogenetic role of the renin-angiotensin system. Recently an insertion/deletion (I/D) polymorphism for the gene encoding the ACE has been described, the deletion type being associated with higher plasma ACE levels. As the intrarenal renin-angiotensin system might also be activated in this setting, we determined the ACE genotype together with other risk factors for the development of diabetic nephropathy in 122 patients with IDDM from a single centre with (n = 63) and without (n = 59) nephropathy. Long-term glycaemic control was evaluated using mean HbA1c values from the last 10 years. The two patient group were comparable with regard to duration of diabetes and glycaemic control as assessed by current HbA1c values. However, mean long-term HbA1c values were significantly higher in patients with diabetic nephropathy as was systemic blood pressure. The DD genotype was more prevalent in patients with renal disease. In the subgroup of patients who had had diabetes for more than 20 years (n = 90), the DD genotype was even more frequent in patients with nephropathy, and blood pressure and long-term HbA1c values were also higher in patients with renal disease. Logistic regression analysis revealed long-term glycaemic control, blood pressure and the ACE genotype to be independent risk factors for the prevalence of diabetic nephropathy. [Diabetologia (1997) 40: 327–331]
    Type of Medium: Electronic Resource
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