fractured zona pellucida oocyte
germinal vesicle-stage oocyte
Springer Online Journal Archives 1860-2000
Abstract Purpose: Our purpose was to determine if the number ofretrieved oocytes, oocyte maturity, morphology, and otherembryological parameters are related to the outcome oftreatment. Methods: This retrospective study on 438 IVF cyclesanalyzes the numbers of retrieved oocytes, fractured zonaoocytes, germinal vesicle-stage oocytes, normally andabnormally fertilized oocytes, pregnancy rate, age of femalepartner, ovarian stimulation protocol, day of hCG injection,and serum estradiol concentration. Results: (1) Pregnancy rate increases with an increase inthe number of retrieved oocytes, (2) a high incidence offractured zona pellucida oocytes has a negative effect onfertilization rate but none on pregnancy rate, (3) a highincidence of immature oocytes is associated with improvedfertilization and pregnancy rates, and (4) an inverserelationship between the presence of immature oocytes and oocyteswith fractured zona pellucida is suggested. Conclusions: Precise oocyte assessment in IVF cyclesprovides informations useful for the analysis and improvementof ovarian stimulation protocols.
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