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  • 1
    ISSN: 1432-0509
    Keywords: Key words: Hepatic veins, thrombosis—Liver neoplasms—Liver neoplasms, CT—Liver neoplasms, MR.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the imaging findings of spiral computed tomography (CT), magnetic resonance (MR) imaging, and MR angiography in a patient with nodular regenerative hyperplasia of the liver associated with Budd–Chiari syndrome. Spiral CT showed multiple enhancing nodules during the hepatic arterial and portal venous phases. MR images showed multiple hyperintense nodules on T1-weighted images and hypointense or isointense nodules on T2-weighted images. MR angiography showed thrombotic occlusion of three hepatic veins, suggesting Budd–Chiari syndrome.
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  • 2
    ISSN: 1432-0509
    Keywords: Key words: Gastrointestinal edema—Edema cirrhosis—Colon edema—CT.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: To evaluate the computed tomographic (CT) features of colonic wall thickening in cirrhotic patients and to determine their prognostic value. Methods: We retrospectively reviewed 28 cirrhotic patients with colonic wall thickening (≥10 mm) on CT. Twenty-six of the 28 patients had hepatocellular carcinoma. The severity of hepatic dysfunction was determined by using the Child–Pugh classification. We analyzed the patterns of bowel wall thickening and degree of portal hypertension on CT and the survival periods after initial CT detection of colonic wall thickening. Results: The involved segment of the colon was diffusely thickened with either scalloped or nodular circumferential configuration. In all patients, the thickened colonic wall enhanced poorly. Although the ascending colon was involved in all patients, the transverse (n= 14) or descending (n= 5) colon was also simultaneously involved. Most patients exhibited an advanced stage of portal hypertension on CT. The median survival period of 25 patients who expired was 34 days, and 21 patients (84%) expired within 3 months. Conclusions: Colonic wall thickening on CT can be used as one of the indicators of poor prognosis in cirrhotic patients. Advanced liver cirrhosis with significantly severe dysfunction is the likely cause of mortality. Therefore, a less aggressive therapeutic approach is recommended if hepatocellular carcinoma is coexistent in these patients.
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  • 3
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  The aim of this study was to subjectively determine the distribution of anaesthesia by mapping areas of sensory loss following inferior alveolar nerve block. Fifty healthy dental students were the subjects of this study (men 32, women 18). They were asked to draw the anaesthetized area on a diagram of the face and tongue 20 min after inferior alveolar nerve block. They evaluated the degree of anaesthesia by touching their faces and moving their tongues. All of the 50 subjects reported anaesthesia in the facial area. Of these, 21 (42%) reported the cutaneous distribution of anaesthesia on mental nerve territory only. Seventeen subjects (34%) reported anaesthesia on mental and buccal nerve territory. Nine subjects (18%) reported anaesthesia on mental, buccal, and auriculotemporal nerve territory. Two subjects (4%) reported anaesthesia on mental and auriculotemporal nerve territory and one subject (2%) on mental, buccal and infra-orbital nerve territory. Forty-seven of the 50 subjects (94%) reported anaesthesia of the tongue with the various degree of anaesthesia according to the area. Of these, 17 subjects (34%) reported strong anaesthesia on the anterior area and weak anaesthesia on the middle part of the tongue. Nineteen subjects (38%) reported strong anaesthesia of the lateral area and weak anaesthesia on the medial area, and 11 subjects (22%) reported anaesthesia on only the lateral side of the tongue. Three subjects (6%) reported no anaesthesia of the tongue. The distribution of anaesthesia of the facial and glossal regions determined subjectively after inferior alveolar nerve block, varies significantly between individuals.
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  • 4
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Sera from 3528 patients with autoimmune disease, and non-autoimmune disease, and 500 normal individuals were studied For the presence of anticentromere antibodies (ACA) by indirect immunofluorescence on HEP-2 cells. Sixty-seven specimens were identified showing discrete speckled staining: 55 (82.1%), 11 (16.4%), and one (1.5%), were from patients with autoimmune disease, non-autoimmune disease and normal control subjects, respectively. These ACA were present frequently in CREST syndrome (55%), Raynaud's disease (29.6%) and primary biliary cirrhosis (30%). Only 16.4% of the antibody positive patients carried a clinical diagnosis of CREST, which means that ACA are not specific for CREST syndrome. High antibody titre persisted irrespective of whether or not the patients had active disease. The ACA were present infrequently in Sjögren's syndrome, systemic lupus erythematosus, rheumatoid arthritis, immune thrombocytopenic purpura, Graves' disease, immune haemolytic anaemia, and vitiligo. Sera from 107 patients with various other autoimmune diseases were negative for ACA.
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  • 5
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Radioaactive samples in cylindrical beakers have been measured using a high purity Ge spectrometer. Self-attenuation effects at various densities of the radioactive samples filled in cylindrical beakers were studied by experimenal and theoretical methods. Coincidence summing effects for specific nuclides were also determined from the measurements of full-energy peak efficiencies in a given source-to-detector geometry.
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  • 6
    ISSN: 0178-515X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract In order to increase the synthesis of bovine growth hormone (bGH) using T7 promoter system in E. coli, the artificial AT-rich block was introduced into the upstream region of a consensus Shine-Dalgarno (SD) sequence and the spacer region (between SD and ATG codon) was enriched with A and T nucleotides. The cells harboring pTAJ plasmids with AT-rich block produced bGH in the range of 3% to 25% and the cells harboring pTBJ plasmids with AT-rich sequence in the spacer region from 0.8% to 20% of total cell proteins. This result suggests that AT rich block and AT nucleotides in the spacer region destabilize mRNA secondary structure, depending on the downstream coding information of bGH gene and also, implying that the disruption of mRNA secondary structure might be a major factor for regulating bGH expression in the translational initiation process.
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  • 7
    ISSN: 1617-4623
    Keywords: Key words Replication initiation ; iciA ; Phosphate regulon ; PhoB ; Escherichia coli
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The IciA protein from Escherichia coli has been shown specifically to inhibit the in vitro initiation of chromosomal DNA replication. However, the in vivo role of IciA has not yet been established. In order to investigate the in vivo function of this protein, expression of the iciA gene was studied by monitoring the β-galactosidase activity specified by an iciA promoter-lacZ fusion inserted into the chromosome. Among the conditions tested (carbon starvation, the stringent response, phosphate starvation, and the SOS response), only phosphate depletion increased iciA expression. Supplementation of phosphate-depleted cultures with inorganic phosphate reduced the β-galactosidase activity to basal levels. Enhanced expression of iciA-lacZ was dependent upon the PhoB protein. PhoB is known to be a transcriptional activator of the Pho regulon, expression of which is activated during phosphate starvation. It was also found that the iciA promoter contains a PhoB protein-binding sequence, termed the Pho box, which is necessary for the activation of genes of the Pho regulon. These results suggest that the iciA gene is a member of the Pho regulon.
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  • 8
    ISSN: 1619-6937
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary A stress solution for a steady state creep material described by the power law is obtained by applying the pseudo-complex stress function which satisfies the biharmonic equation. The relation between the complex stress and the pseudo-stress function is established. The stress function or the stress components can be obtained from the known pseudo stress function. Two specific cases are investigated: 1) the stress field is presumed to contian σ x , σ y and σ xy and 2) the stress field contains only shearing stress, σ xz and σ yz . Both cases presume plane strain, incompressibility and an isothermal condition. Using the solutions obtained from the analysis two boundary value problems are illustrated: 1) the creep continuum is dislocated in the radial direction with constant velocity and 2) the media is dislocated in the axial direction with a constant velocity. If the constant velocity term in the analysis presented herein is replaced with a constant displacement term, then these linear elastic continuum problems are known as Volterra problems. If the problem is reduced to the problem for a perfectly viscous material (m=1.0), the solution for the stress expression is shown to be identical to existing classical solutions.
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  • 9
    ISSN: 1619-6937
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary Three stress solutions for a cylindrical particle on an interface bonded with two identical materials are obtained by using the pseudo-stress function developed previously. The stress solutions correspond to three different bonding mechanisms of a particle interface: 1) complete bonding of a rigid cylindrical particle, 2) radial bonding of the cylindrical rigid particle, and 3) complete bonding with deformable cylindrical particle in a perfectly viscous material. Using stress analysis results, the steady-state vacancy flux distribution at the interface of two materials (material interface) may be expressed as an in terms of the second derivative of normal stress on the interface with respect to two-dimensional space. The behavior of a vacancy sink or a vacancy source is found to be dependent on particle size, relative magnitude of material vs. particle properties, and bonding mechanisms, and loading conditions. In the case of the third stress solution, decohesion at the interface may be prevented by controlling a dimensionless parameter Ω1, which is a function of $${{\sigma _0 ^p } \mathord{\left/ {\vphantom {{\sigma _0 ^p } {\sigma _0 }}} \right. \kern-\nulldelimiterspace} {\sigma _0 }}$$ and the external stress and strain rate hardening exponent, where $$\sigma _0 ^p$$ and σ0 are associated with the particle and matrix constitutive equation $$\bar \sigma = \sigma _0 \dot \bar \varepsilon ^m$$ respectively.
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  • 10
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 77 (2000), S. 1244-1246 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Femtosecond optical pulses are used to generate narrow-band terahertz wave forms via optical rectification in a periodically poled lithium niobate crystal. By cooling the crystal to reduce losses due to phonon absorption, we are able to obtain bandwidths as narrow as 18 GHz at a carrier frequency of 1.8 THz. Temperature-dependent measurements show insignificant bandwidth broadening between 10 and 120 K, although the terahertz power substantially decreases as the temperature increases. Absolute power measurements indicate a conversion efficiency of at least 10−5. © 2000 American Institute of Physics.
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