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  • 1
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung; 20190509-20190511; Wien; DOC19oegu024 /20190408/
    Publication Date: 2019-04-09
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 2
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie; 20190512-20190515; Würzburg; DOCV234 /20190508/
    Publication Date: 2019-05-09
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 3
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie; 20190512-20190515; Würzburg; DOCV092 /20190508/
    Publication Date: 2019-05-09
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 4
    Publication Date: 2018-03-29
    Description: The human brain can quickly adapt to changes in the environment. One example is phonetic recalibration: a speech sound is interpreted differently depending on the visual speech and this interpretation persists in the absence of visual information. Here, we examined the mechanisms of phonetic recalibration. Participants categorized the auditory syllables /aba/ and /ada/, which were sometimes preceded by the so-called McGurk stimuli (in which an /aba/ sound, due to visual /aga/ input, is often perceived as ‘ada’). We found that only one trial of exposure to the McGurk illusion was sufficient to induce a recalibration effect, i.e. an auditory /aba/ stimulus was subsequently more often perceived as ‘ada’. Furthermore, phonetic recalibration took place only when auditory and visual inputs were integrated to ‘ada’ (McGurk illusion). Moreover, this recalibration depended on the sensory similarity between the preceding and current auditory stimulus. Finally, signal detection theoretical analysis showed that McGurk-induced phonetic recalibration resulted in both a criterion shift towards /ada/ and a reduced sensitivity to distinguish between /aba/ and /ada/ sounds. The current study shows that phonetic recalibration is dependent on the perceptual integration of audiovisual information and leads to a perceptual shift in phoneme categorization.
    Keywords: neuroscience, cognition
    Electronic ISSN: 2054-5703
    Topics: Natural Sciences in General
    Published by Royal Society
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  • 5
    Publication Date: 2018-11-01
    Description: Attention can be involuntarily captured by physically salient stimuli, a phenomenon known as bottom-up attention. Typically, these salient stimuli occur unpredictably in time and space. Therefore, in a series of three behavioural experiments, we investigated the extent to which such bottom-up attentional capture is a function of one's prior expectations. In the context of an exogenous cueing task, we systematically manipulated participants' spatial (Experiment 1) or temporal (Experiments 2 and 3) expectations about an uninformative cue and examined the amount of attentional capture by the cue. We anticipated larger attentional capture for unexpected compared to expected cues. However, while we observed attentional capture, we did not find any evidence for a modulation of attentional capture by prior expectation. This suggests that bottom-up attentional capture does not appear modulated by the degree to which the cue is expected or surprising.
    Keywords: neuroscience, psychology, cognition
    Electronic ISSN: 2054-5703
    Topics: Natural Sciences in General
    Published by Royal Society
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  • 6
    Publication Date: 2018-01-31
    Description: Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML, Published online: 30 January 2018; doi:10.1038/leu.2017.348 Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML
    Print ISSN: 0887-6924
    Electronic ISSN: 1476-5551
    Topics: Medicine
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  • 7
    ISSN: 1572-879X
    Keywords: CO adsorption ; infrared spectroscopy ; titania, sulfated ; Lewis acidity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Acidic properties of a TiO2 sample containing approximately 1 wt% S were examined by low-temperature IR spectroscopy of CO and by coadsorption of CO and NH3. Due to the almost negligible OH content of the sample, Brønsted acidity could not be detected. However, Lewis acid sites with enhanced acid strengths as compared to sulfate-free titania could clearly be detected. It is inferred that these sites (namely cus Ti4+ sites) are located in close proximity to sulfate groups and that CO (and NH3) coordinated to the Ti4+ sites interact with the sulfate groups presumably via electronic inductive effects.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1572-879X
    Keywords: sulfated zirconia ; manganese ; iron ; cobalt ; nickel ; zinc ; n-butane isomerization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract First-row transition metals were tested in a flow reactor as promoters of sulfated zirconia for the isomerization ofn-butane at 373 K and 0.005 barn-butane partial pressure. The activity of each of the sulfated zirconia samples increased through a maximum and then decreased with time on stream. In order of increasing activity measured at the maximum, the effect of the promoters increased from right to left in the periodic table: zinc, nickel, cobalt, iron, and manganese. Iron and manganese increased the activity by. 2–3 orders of magnitude. The causes of the promoter action are not elucidated; the promoters may play noncatalytic roles as initiators.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1076
    Keywords: Rachitis ; Antikörperbildung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Das Verhalten der Antikörperbildung in rachitischen und normalen Ratten wurde unter verschiedenen Bedingungen untersucht. Dabei wurden folgende Ergebnisse erzielt: 1. Während der Ausbildung einer experimentellen Rachitis war die humoral meßbare Antikörperbildung gegen Tetanustoxoid und gegen Influenzavirus nicht beeinträchtigt. 2. In bereits rachitischen Versuchstieren konnten 12–14 Tage nach Antigenzufuhr keine Unterschiede in der Bildung hämagglutinations-hemmender Antikörper gegen Influenzavirus und in der Diphtherie-antitoxinbildung festgestellt werden. Die Tetanusantitoxinbildung war unter den gegebenen Versuchsbedingungen in rachitischen Tieren vermindert. 3. Nach Injektion von Schaferythrocyten zeigten die Serumhämagglutinine in der Zeit vom 3. bis 11. Tag nach Antigenzufuhr keine Unterschiede zwischen rachitischen und normalen Ratten. Die Serumhämolysine waren bei den rachitischen Tieren nur am 4. Versuchstag deutlich vermindert; später war diese Differenz nicht mehr nachzuweisen. 4. Im direkten Plaquetest wurde nachgewiesen, daß die Zahl der antikörperbildenden Milzzellen am 3. Tag bei rachitischen Ratten signifikant niedriger lag als bei normalen Tieren. Am 4., 6. und 11. Tag nach Antigeninjektion ergaben sich für rachitische Ratten im Vergleich zu normalen Tieren zwar niedrigere Zahlen an antikörperbildenden Milzzellen. Diese Differenzen ließen sich jedoch statistisch nicht sichern.
    Notes: Summary The antibody-forming capacity of normal and rickety rats was investigated under various experimental conditions. The following results were obtained: 1. During the development of experimental rickets formation of antibody to tetanus toxoid and influenza virus, measureable at the humoral level, was not diminished. 2. When the antigen was injected into animals with existing rickets, the hemagglutinating antibody titers to influenza virus and diphtheria antitoxin, determined 12–14 days after immunization were not lowered as compared to normal controls. Under the experimental conditions, however, tetanus antitoxin formation was reduced. 3. After the injection of sheep red blood cells, there was no difference in the agglutinins detectable in the sera of normal and rickety rats between the 3rd and 11th day after antigenic stimulation. With regard to the serum hemolysins, only on the 4th day after antigen injection was a markedly diminished concentration seen in rickety rats, but the difference later disappeared. 4. By means of the plaque technique the number of antibody—forming spleen cells determined on the 3rd day after immunization was significantly lower in rats with experimental rickets. Reduced numbers of antibody forming spleen cells were found in rickety as against normal rats on the 4th, 6th and 11th days after immunization, but the difference was not statistically significant.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1238
    Keywords: Key words Toxic epidermal necrolysis ; Stevens-Johnson syndrome ; Pulmonary complications ; Fiberoptic bronchoscopy ; Bronchial epithelial necrosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To evaluate the incidence, clinical features, and prognosis of pulmonary complications associated with toxic epidermal necrolysis Design: Prospective study. Setting: Dermatology intensive care unit in Mondor Hospital, France. Patients: 41 consecutive patients. Interventions: On admission, then daily, respiratory evaluation was based on clinical examination, chest X-ray, and arterial blood gas analysis. When clinical symptoms, X-ray abnormalities, or hypoxemia [partial pressure of oxygen (PO2) 〈 80 mm Hg] were present, fiberoptic bronchoscopy was performed. Results: 10 patients presented early manifestations: dyspnea (n = 10), bronchial hypersecretion (n = 7), marked hypoxemia (n = 10) (PO2 = 59 ± 8 mm Hg). Chest X-ray was normal (n = 8) or showed interstitial infiltrates (n = 2). In these 10 patients, fiberoptic bronchoscopy demonstrated sloughing of bronchial epithelium in proximal airways. Delayed pulmonary complications occurred in 6 of these 10 patients from day 7 to day 15: pulmonary edema (n = 2), atelectasis (n = 1), bacterial pneumonitis (n = 4). Mechanical ventilation was required in 9 patients. A fatal outcome occurred in 7 patients. Seven patients did not develop early pulmonary manifestations (PO2 on admission 87 ± 6 mm Hg) but only delayed pulmonary symptoms related to atelectasis (n = 1), pulmonary edema (n = 4), and bacterial pneumonitis (n = 3); bronchial epithelial detachment was not observed. None of them required mechanical ventilation and all recovered with appropriate therapy. Conclusions:“Specific” involvement of bronchial epithelium was noted in 27 % of cases and must be suspected when dyspnea, bronchial hypersecretion, normal chest X-ray, and marked hypoxemia are present during the early stages of toxic epidermal necrosis. Bronchial injury seems to indicate a poor prognosis, as mechanical ventilation was required for most of these patients and was associated with a high mortality.
    Type of Medium: Electronic Resource
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