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  • 1
    Unknown
    Champaign, Ill : Project Gutenberg
    Keywords: Zoology, Juvenile literature. ; Animal behavior, Juvenile literature.
    ISBN: 0-585-01472-8
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  • 2
    Unknown
    Hoboken, N.J : BiblioBytes
    Keywords: Philosophy, Ancient.
    ISBN: 0-585-04945-9
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  • 3
    Unknown
    Cambridge : Published for the Society for Experimental Biology by the Company of Biologists
    Call number: QH301Z:36/42
    Keywords: Plants, Effect of temperature on
    Pages: 415, x p.
    ISBN: 0948601205
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    QH301Z:36/42 available
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  • 4
    Call number: 09-Q:337
    Keywords: Biometry ; Probability
    Notes: A Wiley publication in applied statistics.
    Pages: xvi, 313 p.
    Signatur Availability
    09-Q:337 departmental collection or stack – please contact the library
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  • 5
    Keywords: Medicine ; Cancer Research ; Gene Expression ; Molecular Biology ; Biochemistry ; Cell Biology ; Biomedicine ; Gene Expression ; Biochemistry, general ; Cell Biology ; Molecular Medicine ; Cancer Research ; Springer eBooks
    Description / Table of Contents: PART I Exogenous RNAa -- PART II Endogenous RNAa -- PART III RNA activation guided by other small RNAs -- PART IV Developing RNAa-based therapeutics --
    Abstract: This book offers an essential guide to RNA activation (RNAa), an emerging and fascinating new field. RNAa is a small RNA-guided and Argonaute-dependent gene regulation phenomenon in which promoter-targeted short double-stranded RNAs (dsRNAs) induce target gene expression at the transcriptional level. It occurs primarily in the nucleus and can be mediated by artificially designed short duplex RNAs that target regulatory sequences (e.g., promoters, genes’ 3’ termini and enhancers) and naturally occurring small RNAs (e.g., miRNAs and C. elegans 22G-RNAs). With contributions from internationally respected RNA experts, this book provides comprehensive coverage of different RNAa mechanisms and a timely update on recent advances in RNAa research, with a focus on developing RNAa-based therapeutics. Special chapters are also devoted to the topics of gene activation induced by antisense oligonucleotides and the CRISPR system. As the first book to cover RNAa, it will be of interest to a wide audience, from scientists in academia and the pharmaceutical industry to clinicians who wish to further explore the biology of RNAa and related phenomena, so as to harness their full potential for use in biotechnology and drug development
    Pages: XIV, 239 p. 45 illus., 38 illus. in color. : online resource.
    ISBN: 9789811043109
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  • 6
    Keywords: Life sciences ; Biochemistry ; Life sciences ; Biochemistry, general ; Springer eBooks
    Description / Table of Contents: Synthesis of Chain-end Functionalized Glycopolymers via Cyanoxyl Mediated Free Radical Polymerization (CMFRP) -- Protecting-group-free Synthesis of Well-defined Glycopolymers Featuring Negatively Charged Oligosaccharides -- Glycopolymers Prepared by Ring-opening Metathesis Polymerization Followed by Glycoconjugation Using a Triazole Forming ‘Click’ Reaction -- Protecting-group-free Synthesis of Glycopolymers and Their Binding Assay with Lectin and Influenza Virus -- Carbohydrate-based Initiators for the Cationic Ring-opening Polymerization of 2-Ethyl-2-oxazoline -- Heterofunctional Glycopolypeptides by Combination of Thiol-ene Chemistry and NCA Polymerization -- Preparation of Proteoglycan Mimetic Graft Copolymers -- Galactosylated Polymer Nano-objects by Polymerization-Induced Self-Assembly, Potential Drug Nanocarriers -- Synthetic Approach to Biotinylated Glyco-Functionalized Quantum Dots: A New Fluorescent Probes for Biomedical Applications -- Surface Modification of Polydivinylbenzene Microspheres with a Fluorinated Glycopolymer using Thiol-Halogen Click Chemistry -- Glycopolymer-grafted Polymer Particles for Lectin Recognition -- Synthesis of Non-spherical Glycopolymer-decorated Nanoparticles: Combing Thiol-ene with Catecholic Chemistry -- Synthetic Approach To Glycopolymer Base Nanoparticle Gold(I) Conjugate: A New Generation Of Therapeutic Agents -- Multivalent Glycopolymer-coated Gold Nanoparticles -- Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry -- Oriented Immobilized Sialyloligo-Macroligand Microarray -- Glycocalyx Remodeling with Glycopolymer-based Proteoglycan Mimetics
    Abstract: This volume details methods and protocols for the synthesis and characterization of glycopolymers and their biomedical applications. Chapters are divided into three parts covering synthesis and characterization of glycopolymers; glycopolymer-nanoparticle conjugates; and surface immobilized glycopolymers. ℗ Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. ℗ Authoritative and practical, Macro-Glycoligands: Methods and Protocols aims to ensure successful results in the further study of this vital field
    Pages: XIII, 226 p. 73 illus., 41 illus. in color. : online resource.
    Edition: 1st ed. 2016.
    ISBN: 9781493931309
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  • 7
    Keywords: Medicine ; Human Genetics ; Microbial genetics ; Biomedicine ; Human Genetics ; Microbial Genetics and Genomics ; Springer eBooks
    Description / Table of Contents: Microarray Transposon Tracking for the Mapping of Conditionally Essential Genes in Campylobacter jejuni -- Identifying Essential Streptococcus sanguinis Genes Using Genome-Wide Deletion Mutation -- Defining Essential Genes and Identifying Virulence Factors of Porphyromonas gingivalis by Massively-Parallel Sequencing of Transposon Libraries (Tn-seq) -- Identification of Essential Genes and Synthetic Lethal Gene Combinations in Escherichia coli K-12 -- Identification of Genes Essential for Leptospirosis -- Identifying Essential Genes in Mycobacterium tuberculosis by Global Phenotypic Profiling -- Essential Genes in the Infection Model of Pseudomonas aeruginosa-PCR-Based Signature-Tagged Mutagenesis -- Genome-Wide Synthetic Genetic Screening by Transposon Mutagenesis in Candida albicans -- An Integrated Machine-Learning Model to Predict Prokaryotic Essential Genes -- A Statistical Framework for Improving Genomic Annotations of Transposon Mutagenesis (TM) Assigned Essential Genes -- A Proposed Essential Gene Discovery Pipeline: A Campylobacter jejuni Case Study -- Computational Prediction of Essential Metabolic Genes Using Constraint-Based Approaches -- Three Computational Tools for Predicting Bacterial Essential Genes -- Gene Essentiality Analysis Based on DEG 10, an Updated Database of Essential Genes -- A Novel Essential Domain Perspective for Exploring Gene Essentiality
    Abstract: This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans. Given the significant advancement in the computational predictions of microbial essential genes, the second half of the book examines four main types of approaches: comparative genomics, supervised machine learning, constraint-based methods, and corrections of transposon mutagenesis data, as well as databases and servers that are often used in studying gene essentiality. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Gene Essentiality: Methods and Protocols will aid researchers who wish to further our knowledge in this vital field of study
    Pages: XI, 248 p. 42 illus., 15 illus. in color. : online resource.
    ISBN: 9781493923984
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  • 8
    Keywords: Molecular Biology ; Nephrology ; Diabetes ; Molecular Medicine ; Nephrology ; Diabetes ; Springer eBooks
    Description / Table of Contents: Diabetic Nephropathy: An Overview -- Modeling Podocyte Biology Using Drosophila Nephrocytes -- A Technique for Studying Glomerular Filtration Integrity in the Zebrafish Pronephros -- Modeling Human Diabetic Kidney Disease by Combining Hyperglycemia and Hypertension in a Transgenic Rodent Model -- Isolating and Culturing Mouse Podocyte Cells to Study Diabetic Nephropathy -- Histological Examination of the Diabetic Kidney -- Sample Preparation and Stereological Methods for the Study of Glomerular Ultrastructure Using Electron Microscopy -- Tissue Clearing and Deep Imaging of the Kidney Using Confocal and Two-Photon Microscopy -- Transcutaneous Measurement of Glomerular Filtration Rate in Rodents -- An In Vitro Method to Analyze Glucose Uptake in Podocytes -- Glomerular Endothelial Cells: Assessment of Barrier Properties In Vitro -- Methods to Detect Endoplasmic Reticulum Stress and Apoptosis in Diabetic Nephropathy -- Isolating Urinary Extracellular Vesicles as Biomarkers for Diabetic Disease -- Examining Cell-Cell Interactions in the Kidney Using AFM Single-Cell Force Spectroscopy -- Genetic Strategies to Understand Human Diabetic Nephropathy: Wet-Lab Approaches -- Genetic Strategies to Understand Human Diabetic Nephropathy: In Silico Strategies for Molecular Data - Association Studies -- Assessment of Urinary MicroRNAs by Quantitative Polymerase Chain Reaction in Diabetic Nephropathy Patients -- Metabolomic and Proteomic Techniques for Establishing Biomarkers and Improving Our Understanding of Pathophysiology in Diabetic Nephropathy -- Formation of Mature Nephrons by Implantation of Human Pluripotent Stem Cell-Derived Progenitors into Mice -- Generating Mutant Renal Cell Lines Using CRISPR Technologies
    Abstract: This book provides a toolkit of novel research approaches for investigators to study diabetic nephropathy, including critical experimental models from the fly to the fish, cells in culture, and in vivo mammalian approaches. The collection also explores powerful techniques to image the kidney, such as traditional histological techniques as well as electron, confocal, and two-photon microscopy, pathophysiology of the diabetic kidney, and gene editing and regenerative medicine. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Diabetic Nephropathy: Methods and Protocols seeks to foster new research directions and inspire ideas to enhance our understanding of diabetic nephropathy and to develop treatments for this condition
    Pages: XIII, 342 p. 109 illus., 95 illus. in color. : online resource.
    Edition: 1st ed. 2020.
    ISBN: 9781493998418
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  • 9
    Keywords: Biomedical Engineering ; Food—Biotechnology ; Biomedical Engineering/Biotechnology ; Food science ; Springer eBooks
    Description / Table of Contents: Nutraceuticals: definition, kinds and applications -- Construction of microbial cell factories by systems and synthetic biotechnology -- Microbial production of functional organic acids -- Microbial production of oligosaccharides and polysaccharides -- Microbial production of flavonoids -- Microbial production of natural food colorants -- Microbial production of vitamins -- Microbial production of oils and fatty acids -- Microbial production of nutraceuticals: challenges and prospects
    Abstract: This book discusses systems and synthetic biotechnologies for the production of nutraceuticals, and summarizes recent advances in nutraceutical research in terms of the physiological effects on health, potential applications, drawbacks of traditional production processes, characteristics of production strains, and advances in microbial production based on systems and synthetic biotechnology. It also examines future directions in the microbial production of nutraceuticals using systems and synthetic biology. The book is intended for researchers and graduate students in the field of molecular biology and industrial biotechnology as well as staff working in the nutraceutical industry
    Pages: V, 208 p. 38 illus., 28 illus. in color. : online resource.
    Edition: 1st ed. 2019.
    ISBN: 9789811504464
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  • 10
    Unknown
    Hoboken, New Jersey : Wiley
    Call number: E020:84
    Keywords: Molecular Imaging ; Chemical Phenomena ; Diagnostic Imaging
    Description / Table of Contents: 1. An Introduction to Molecular Imaging -- 2. Chemical Methodology for Labelling and Bioconjugation -- 3. Recent Developments in the Chemistry of [ 18F]Fluoride for PET -- 3. Recent Developments in the Chemistry of [ 18F]Fluoride for PET -- 4. Carbon-11, Nitrogen-13, and Oxygen-15 Chemistry: An Introduction to Chemistry with Short-Lived Radioisotopes -- 5. The Chemistry of Inorganic Nuclides (86Y, 68Ga, 64Cu, 89Zr, 124I) -- 6. The Radiopharmaceutical Chemistry of Technetium and Rhenium -- 7. The Radiopharmaceutical Chemistry of Gallium(Ill) and Indium(III) for SPECT Imaging -- 8. The Chemistry of Lanthanide MRI Contrast Agents -- 9. Nanoparticulate MRI Contrast Agents -- 10. CEST and PARACEST Agents for Molecular Imaging -- 11. Organic Molecules for Optical Imaging -- 12. Application of d- and f-Block Fluorescent Cell Imaging Agents -- 13. Lanthanide-Based Upconversion Nanophosphors for Bioimaging -- 14. Microbubbles: Contrast Agents for Ultrasound and MRI -- 15. Non-Nanoparticle-Based Dual-Modality Imaging Agents -- 16. Chemical Strategies for the Development of Multimodal Imaging Probes Using Nanoparticles
    Abstract: "Covering all the fundamentals of modern imaging methodologies, including their techniques and application within medicine and industry, The Chemistry of Molecular Imaging focuses primarily on the chemistry of probes and imaging agents, as well as chemical methodology for labelling and bioconjugation. Written by an interdisciplinary team of experts, this book investigates the chemistry of molecular imaging and helps to educate non-chemists already involved in the area of molecular imaging. It addresses all the major modalities and techniques, such as MRI, positron emission tomography, single photon emission computed tomography, ultrasound, and fluorescence/optical imaging"--
    Pages: xii, 395 pages, [24] pages of plates : illustrations (some color)
    ISBN: 9781118093276
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    E020:84 departmental collection or stack – please contact the library
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