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  • 1
    Publication Date: 2018-10-13
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 2
    ISSN: 1432-1106
    Keywords: Key words Eye-head coordination ; Bilateral vestibular loss ; Adaptation ; Vestibulo-ocular reflex ; Vestibulo-saccadic reflex ; Saccadic gaze shift ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Eye-head coordination during saccadic gaze shifts normally relies on vestibular information. A vestibulo-saccadic reflex (VSR) is thought to reduce the eye-in-head saccade to account for current head movement, and the vestibulo-ocular reflex (VOR) stabilizes postsaccadic gaze while the head movement is still going on. Acute bilateral loss of vestibular function is known to cause overshoot of gaze saccades and postsaccadic instability. We asked how patients suffering from chronic vestibular loss adapt to this situation. Eye and head movements were recorded from six patients and six normal control subjects. Subjects tracked a random sequence of horizontal target steps, with their heads (1) fixed in primary position, (2) free to move, or (3) preadjusted to different head-to-target offsets (to provoke head movements of different amplitudes). Patients made later and smaller head movements than normals and accepted correspondingly larger eye eccentricities. Targeting accuracy, in terms of the mean of the signed gaze error, was better in patients than in normals. However, unlike in normals, the errors of patients exhibited a large scatter and included many overshoots. These overshoots cannot be attributed to the loss of VSR because they also occurred when the head was not moving and were diminished when large head movements were provoked. Patients’ postsaccadic stability was, on average, almost as good as that of normals, but the individual responses again showed a large scatter. Also, there were many cases of inappropriate postsaccadic slow eye movements, e.g., in the absence of concurrent head movements, and correction saccades, e.g., although gaze was already on target. Performance in patients was affected only marginally when large head movements were provoked. Except for the larger lag of the head upon the eye, the temporal coupling of eye and head movements in patients was similar to that in normals. Our findings show that patients with chronic vestibular loss regain the ability to make functionally appropriate gaze saccades. We assume, in line with previous work, three main compensatory mechanisms: a head movement efference copy, an active cervico-ocular reflex (COR), and a preprogrammed backsliding of the eyes. However, the large trial-to-trial variability of targeting accuracy and postsaccadic stability indicates that the saccadic gaze system of patients does not regain the high precision that is observed in normals and which appears to require a vestibular head-in-space signal. Moreover, this variability also permeates their gaze performance in the absence of head movements.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1433-7347
    Keywords: Key words Knee ; Arthroscopy ; Meniscectomy ; Rehabilitation ; Physical therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Sports Science
    Notes: Abstract To evaluate the effect of physiotherapy after partial arthroscopic meniscectomy, we performed a prospective, randomised and partially blinded study. This pilot study was performed from October 1996 to June 1997. The control group received the standard treatment, consisting of verbal and written advice and exercises. The physiotherapy group performed exercises according to a dynamic protocol under the supervision of a physiotherapist. During a 3-week period, nine treatment sessions were given of 30 min each. Twenty patients, who had undergone arthroscopic meniscectomy without any other pathology of the knee, were randomised into two groups of ten patients each. The effects of therapy were evaluated by a blinded observer. We measured the distance and height of one-leg jumps (hops), the VAS pain scale, the Tegner and Lysholm scores and the SARS/FORS score. Recovery and satisfaction with the treatment were also evaluated. The effect measurements were performed at 7 (T1), 14 (T2), 21 (T3) and 28 days (T4) following surgery. Statistical analysis was performed with the Student’s t-test. The physiotherapy group showed significantly better results than the control group regarding the SARS score, the hop test and the distance jumps. Moreover, the measurements showed clear progression in favour of the physiotherapy group. In conclusion, exercising under the supervision of a physiotherapist led to high patient satisfaction and good functional rehabilitation after partial arthroscopic meniscectomy.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 8 (1962), S. 34-36 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0630
    Keywords: 34.00 ; 61.16 ; 81.40
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract 15N 2 + ions were implanted into c-Si with an energy of 5 keV/atom and fluences ranging from 5×1016 to 2×1017 atoms/cm2 at RT to form ultrathin silicon-nitride layers (SiN x ) with different N/Si ratios depending on the fluences (up to an overstoichiometric N/Si ratio of 1.65). The 15N depth distributions were analysed by the resonant nuclear reaction 15N(p, αγ)12C(E res=429 keV). The implanted samples were processed by Electron Beam Rapid Thermal Annealing (EB-RTA) at 1150° C for 15 s (ramping up and down 5° C/s). The chemical structure of the 15N implantation into Si was investigated by EXAFS and NEXAFS. Channeling-RBS (4He+, E 0=1.5 MeV) measurements were performed to observe the transition region (disordered-Si layer, d-Si) being underneath of the SiN x layer (typical values of layer thicknesses:SiN x 24 nm, d-Si 6 nm).
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The blink reflex evoked by unilateral electrical stimulation was studied in 7 patients with Neurofibromatosis and 50 normal persons. Studying data of the early R1 reflex, there was no difference between normal persons and patients with von Recklinghausen disease. A slightly, but significantly increased reflex latency of the direct R2 was recognized in the majority of the patients with Neurofibromatosis.
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  • 7
    ISSN: 1618-2650
    Keywords: Analyse von Harnkonkrementen ; Methodenvergleich
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0749-503X
    Keywords: Saccharomyces cerevisiae ; STRE ; stress response ; genomics ; bioinformatics ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Stress response elements (STREs, core consensus AG4 or C4T) have been demonstrated previously to occur in the upstream region of a number of genes responsive to induction by a variety of stress signals. This stress response is mediated by the homologous transcription factors Msn2p and Msn4p, which bind specifically to STREs. Double mutants (msn2 msn4) deficient in these transcription factors have been shown to be hypersensitive to severe stress conditions. To obtain a more representative overview of the set of yeast genes controlled via this regulon, a computer search of the Saccharomyces cerevisiae genome was carried out for genes, which, similar to most known STRE-controlled genes, exhibit at least two STREs in their upstream region. In addition to the great majority of genes previously known to be controlled via STREs, 69 open reading-frames were detected. Expression patterns of a set of these were examined by grid filter hybridization, and 14 genes were examined by Northern analysis. Comparison of the expression patterns of these genes demonstrates that they are all STRE-controlled although their detailed expression patterns differ considerably. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 0168-583X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Störungen der Durchblutung und des Gas- und Stoffwechsels erfordern ein umfangreiches Programm an Laboruntersuchungen zur postoperativen Überwachung. Die Vielzahl der notwendigen Einzeluntersuchungen zur Beurteilung des Säurebasenhaushalts, der Blutgerinnung und der Blutzusammensetzung hinsichtlich hämatologischer und chemischer Meßgrößen legt die Frage nahe nach den Möglichkeiten zur Durchführung unter den Bedingungen des Nacht- und Feiertagsdienstes. Die Schwierigkeiten und Voraussetzungen für die zuverlässiges Beurteilung werden dargestellt. Eine Erweiterung der diagnostischen Möglichkeiten ist in naher Zukunft nur durch organisatorische Verbesserungen und engere Zusammenarbeit zwischen Klinik und Laboratorium zu erwarten, da neue Verfahren nicht zur Verfügung stehen.
    Notes: Summary Disturbances of the blood supply, gas exchange and metabolism require an extensive program of laboratory investigations in postoperative supervision. The large number of individual investigations necessary to evaluate the acid-base status, the hemostasis and the blood composition with regard to hematological and chemical data raises the question of the possibility of having them performed during night duty. The difficulties involved in making a reliable assessment and the conditions necessary for this are demonstrated. Any improvement in the situation in the near future can only result from better organization and closer cooperation between clinic and laboratory, since new, relevant methods of investigation are not yet available.
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