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  • 1
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We investigated the superficial microtopography of the normal skin of 11 volunteers (not exposed to sunlight during the last 4 months), before and after sun exposure for 5 days at high altitudes of 2900–4559 m. The experiments were carried out on Mount Rosa in Italy, and cutaneous replicas using silicone resin were taken every day after 7 h of sun exposure. Casts were taken from the forehead, glabella, dorsum nasi, radial side (protected with a cream SPF 9.72) and ulnar side of the back of the hands, the only areas not protected. A total of 422 replicas were metallized with gold-palladium and observed under Zeiss 940A scanning electron microscope. The images were elaborated and analysed on computer with appropriate software supplying geometrical features of cutaneous surface using parameters proposed by Takahashi (1994). A Student’s test for paired series was used to analyse the differences before and after 1–5 days of exposure giving uniform and significant data compared with controls. Using cutaneous replicas we demonstrated that repeated exposure of skin to sunlight in a short time elicits temporary defence mechanisms with increased obstruction of cutaneous pores, deepening of primary cutaneous furrows and shallowing of part of the secondary furrows; the two latter alterations are the consequence of reactive oedema.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 149 (2003), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ectopic nail is an extremely rare condition related to acquired or congenital anomalies. Almost 40 cases are reported in the literature, mostly in Japanese patients. In the majority of these patients, ectopic nails developed in the dorsal aspect of the fingers; they are associated in some cases with acquired or congenital growth anomalies or to polydactyly. Recently, we observed two male adult patients with true ectopic nails of the foot (sole and heel). Both patients were not affected by ectodermic dysplasia or foot malformations. The lesion relapsed after surgical excision in one case. Histology showed features of a well-developed and normal nail plate and matrix. A transmission electron microscope study was done in one case, showing typical aspects of onychocytes. The other nail was reproduced by a silicone replica technique and its superficial texture, shape and relationship with surrounding tissue were analysed by scanning electron microscopy.
    Type of Medium: Electronic Resource
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