Springer Online Journal Archives 1860-2000
Conclusions In this population of severely ill patients, SOFA score decrease over time, both in survivors and in non-survivors; it's discriminative power increases, but remains lower than general severity scores. At admission, best discrimination was achieved by cardiovascular failure, but after 5 days in the ICU, respiratory failure was superior. The impact on prognosis of organ failure was analysed, with cardiovascular failure at admission, and respiratory, renal, and hematological on 5th day having the greatest impact on prognosis. The relationships among the six organic systems analysed can be described in terms of a two dimensional structure; this point needs further research, since it can reveal new insights in the sequence and patterns of evolution of multiple organ disfunction/failure syndrome.
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