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  • 1
    Keywords: Life sciences ; Cytology ; Laboratory animals ; Life sciences ; Cell Biology ; Animal Models ; Springer eBooks
    Description / Table of Contents: Drosophila melanogaster Oogenesis: An Overview -- Basic Techniques in Drosophila Ovary Preparation -- Mosaic Analysis in the Drosophila Melanogaster Ovary -- Genetic Mosaic Analysis of Stem Cell Lineages in the Drosophila Ovary -- Culturing Drosophila Egg Chambers and Investigating Developmental Processes through Live Imaging -- Border Cell Migration: A Model System for Live Imaging and Genetic Analysis of Collective Cell Movement -- Visualizing Microtubule Networks during Drosophila Oogenesis using Fixed and Live Imaging­­Visualization of Actin Cytoskeletal Dynamics in Fixed and Live Drosophila Egg Chambers -- Single Molecule RNA in situ Hybridization (smFISH) and Immunofluorescence (IF) in the Drosophila Egg Chamber -- Fluorescent In Situ Hybridization of Nuclear Bodies in Drosophila melanogaster Ovaries -- Ultrastructural Analysis of Drosophila Ovaries by Electron Microscopy -- Immuno-Electron Microscopy and Electron Microscopic in situ Hybridization for Visualizing piRNA Biogenesis Bodies in Drosophila Ovaries -- Visualizing Cytoophidia Expression in Drosophila Follicle Cells via Immunohistochemistry.-Detection of Cell Death and Phagocytosis in the Drosophila Ovary -- Analysis of Cell Cycle Switches in Drosophila Oogenesis -- Global Run-On Sequencing (GRO-seq) Library Preparation from Drosophila Ovaries -- Bioinformatics Analysis to Identify RNA-protein Interactions in Oogenesis
    Abstract: This volume provides current up-to-date protocols for preparing the ovary for various imaging techniques, genetic protocols for generating mutant clones, mosaic analysis and assessing cell death. Chapters address methods for performing genome wide gene expression analysis and bioinformatics for studies of RNA-protein interactions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. ℗ Authoritative and cutting-edge, Drosophila Oogenesis: Methods and Protocols aims to ensure successful results in the further study of this vital field
    Pages: XI, 245 p. 51 illus., 29 illus. in color. : online resource.
    Edition: 1st ed. 2015.
    ISBN: 9781493928514
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  • 2
    Call number: 08-NMR
    Keywords: Chest / Tomography ; Chest / Magnetic resonance imaging ; Magnetic Resonance Imaging ; Thoracic radiography ; Tomography, X-Ray Computed
    Notes: Rev. ed. of: Computed tomography of the thorax. c1984.
    Pages: xiii, 606 p. : ill.
    Edition: 2nd ed.
    ISBN: 0881675679
    Signatur Availability
    08-NMR departmental collection or stack – please contact the library
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  • 3
    Unknown
    New York, NY : Landes Bioscience and Springer Science+Business Media, LLC
    Keywords: Medicine ; Biomedicine ; Biomedicine general ; Springer eBooks
    Pages: : digital
    ISBN: 9781441963154
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  • 4
    Keywords: Medicine ; Pharmaceutical technology ; Biomedicine ; Pharmaceutical Sciences/Technology ; Biomedicine general ; Springer eBooks
    Description / Table of Contents: Introduction -- Current Approaches To APSD Measurement of OIPs Based on Inertial Impaction -- Physical Causes of APSD Changes in Aerosols From OIPs and their Impact on Cascade Impactor Measurements -- Good Cascade Impactor Practices -- The AIM and EDA Concepts: Why they are Needed -- Product Lifecycle Approach to Cascade Impaction Measurements -- Theoretical Basis for the EDA Concept -- Performance Characterization of EDA and its Potential to Improve Decision Making in Product Batch Release -- Verification of the EDA Concept through an Assessment of Theoretical Failure Modes, Failure Mode Analysis and Case Studies with Real Data -- Validating AIM-Based Instrumentation and Associated Measurement Techniques -- The Regulatory and Compendial Acceptance Pathways for AIM and EDA -- Applying the AIM Concept in Support of Developing Improved In Vitro-In Vivo Relationships for OIPs -- Future Directions for the AIM and EDA Concepts -- Conclusions
    Abstract: Aerodynamic particle size characteristics of orally inhaled products (OIPs) are critical to their performance.℗ Testing based on cascade impaction has been the primary tool used to characterize this critical quality attribute and is a regulatory expectation for Quality Control purposes.℗ In recent years, there have been substantial efforts directed at improving aerodynamic particle size determinations.℗ Good Cascade Impactor Practices, AIM and EDA for℗ Orally Inhaled Products brings together for the first time a review of best practices for performing cascade impactor testing with a thorough discussion of the℗ recently introduced concepts of abbreviated impactor measurements (AIM) and efficient data analysis (EDA). ℗ ℗ Topics covered include:℗ ℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Review of pharmacopeial methods (US and European) for assessment of aerodynamic particle size distribution (APSD) of℗ OIPs. ℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Physical processes that underlie aerosol formation from OIPs and the mechanisms that affect the APSD.℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Good cascade impactor practice (GCIP) related to either full resolution or abbreviated impactor measurements.℗ ℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Introduction of the AIM and EDA concepts.℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Selection of the type of testing through the development lifecycle of an OIP.℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Theoretical basis for EDA.℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Performance evaluation of EDA as a quality control element.℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Case studies related to the application of℗ EDA.℗ ℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Experimental studies validating the AIM concept conducted by European Pharmaceutical Aerosol Group (EPAG) and the Cascade Impaction Working Group of the International Pharmaceutical Aerosol Consortium on Regulation and Science (IPAC-RS).℗ ℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Regulatory and compendial pathways to adoption of AIM and EDA. ℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Exploration and extension of AIM as a potential approach to measures that could be more predictive of particle deposition in the human respiratory tract.℗ ℗ This comprehensive volume was written by a group of prominent international experts in aerosol testing led by members of the Cascade Impaction Working Group of IPAC-RS.℗ IPAC-RS is an international association of pharmaceutical companies committed to advancing consensus-based, scientifically driven standards and regulations for orally inhaled and nasal drug products
    Pages: : digital.
    ISBN: 9781461462965
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  • 5
    Unknown
    New York : Academic Press
    Call number: 08-NMR
    Keywords: Nuclear Magnetic Resonance ; Biology / Research ; Medicine / Research
    Pages: ix, 354 p. : ill.
    ISBN: 0120255626
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    08-NMR departmental collection or stack – please contact the library
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  • 6
    Keywords: Medicine ; Family medicine ; Internal Medicine ; Cardiology ; Nursing ; Medicine & Public Health ; Internal Medicine ; Cardiology ; General Practice / Family Medicine ; Nursing ; Springer eBooks
    Pages: : digital
    ISBN: 9781603279635
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  • 7
    Call number: 04-GEN:215
    Keywords: Chromosomes
    Pages: ix, 523 p. : ill.
    ISBN: 047156124X
    Signatur Availability
    04-GEN:215 departmental collection or stack – please contact the library
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  • 8
    Keywords: Medicine ; Neurosciences ; Ophthalmology ; Neurobiology ; Biomedicine ; Neurosciences ; Ophthalmology ; Neurobiology ; Springer eBooks
    Description / Table of Contents: 1. Introduction -- 2. Fundamental Retinal Circuitry for Circadian Rhythms -- 3. Circadian photoreception: from phototransduction to behaviour -- 4. Role of Melatonin and Dopamine in the Regulation of Retinal Circadian Rhythms -- 5. Circadian Organization of the Vertebrate Retina -- 6. Rhythmicity of the Retinal Pigment Epithelium -- 7. Retinal Circadian Rhythms in Mammals Revealed Using Electroretinography -- 8. Circadian Clock and Light Induced Retinal Damage -- 9. Circadian Rhythms and Vision in Zebrafish -- 10. Circadian Modulation of the Limulus Eye for Day and Night Vision -- 11. Molluscan Ocular Pacemakers: Lessons Learned. ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗
    Abstract: The retina plays a critical role in the organization of the circadian system by synchronizing the braiń€™s central clock with the external day through transduction of the daily light/dark cycle.℗ However, the substantial variation in luminance imposed on the retina between day and night also poses a challenge to its role as a sensory tissue ́€“ how is it possible to faithfully encode the enormous dynamic range of luminance that can exceed 10 orders of magnitude? The Retina and Circadian Rhythms summarizes the knowledge accumulated over the last 30 years about the organization of the retinal circadian clock in many different species, concentrating on the roles that this circadian system plays in retinal function. About the Series: The Springer Series in Vision Research is a comprehensive update and overview of cutting edge vision research, exploring, in depth, current breakthroughs at a conceptual level. It details the whole visual system, from molecular processes to anatomy, physiology and behavior and covers both invertebrate and vertebrate organisms from terrestrial and aquatic habitats. Each book in the Series is aimed at all individuals with interests in vision including advanced graduate students, post-doctoral researchers, established vision scientists and clinical investigators.The series editors are N. Justin Marshall, Queensland Brain Institute, The University of Queensland, Australia and Shaun P. Collin, Neuroecology Group within the School of Animal Biology and the Oceans Institute at the University of Western Australia
    Pages: VIII, 238 p. 50 illus., 33 illus. in color. : online resource.
    ISBN: 9781461496137
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  • 9
    Unknown
    Philadelphia, PA : Saunders/Elsevier
    Call number: QS517:17
    Keywords: Histology ; Histology
    Notes: Based on: Color textbook of histology / Leslie P. Gartner, James L. Hiatt. 3rd ed. c2007.
    Pages: ix, 342 p. : ill. (chiefly col.)
    ISBN: 9780702031144
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    QS517:17 available
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  • 10
    Unknown
    Cambridge [Cambridgeshire] : Cambridge University Press
    Call number: 08-MATH
    Keywords: Electric engineering / Mathematics ; Finite element method
    Pages: ix, 209 p. : ill.
    ISBN: 0521273102
    Signatur Availability
    08-MATH departmental collection or stack – please contact the library
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