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  • 1
    Keywords: Medicine ; Cancer Research ; Pharmacology ; Oncology ; Biomedicine ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer eBooks
    Description / Table of Contents: Serum uric acid and biomarkers of lumbar spine bone mineral density -- Use of alkaline phosphatase (ALP) activity and disease severity to determine secular changes in bone disease as applied to Paget's disease of the bone -- Bone Turnover and Spinal Cord Injury -- Bone-related proteins as markers in vascular remodelling -- Serum Sclerostin as Biomarker in Osteogenesis Imperfecta -- Parathyroid Hormone (PTH) assays and applications to bone disease: Overview on methodology -- Registered microcomputed tomography data as a four dimensional imaging biomarker of bone formation and resorption -- Use of bone biomarkers after weight loss: Example of bariatric surgery -- Adiponectin as biomarker of osteoporosis -- Effect of statins on bone turnover markers -- Chitinases as biomarkers in bone studies -- Hormone relaxin as biomarker for bone health and disease -- Panoramic radiomorphometric indices of mandible: Biomarker for osteoporosis -- Hip Fracture Risk is Strongly Related to Circulating Levels of the Advanced Glycation End-product Carboxy-Methyl Lysine (CML) -- Effects of glucose on bone markers: Overview of current knowledge with focus on diabetes, glucose, and bone markers -- Traditional medicine and use of bone biomarkers -- Osteosarcoma Biomarkers discovery using "omics" approaches -- Creatine kinase as biomarker in osteogenesis imperfecta -- Ameloblastin as biomarker of bone -- Biomarker genes in autosomal dominant osteopetrosis type II (ADO II) -- Bone markers in Rett syndrome -- Bone Specific Alkaline Phosphatase and Exercise -- Bone turnover markers and glucocorticoid treatments -- Overview of biochemical markers of bone metabolism -- Biomarkers of natural radionuclides in bone and teeth -- Bone markers throughout sexual development: epidemiological significance and population-based findings -- Parathyroid hormone (PTH) and the relationship between PTH and bone health: structure, physiology, actions, and ethnicity -- Quantitative ultrasound as a biomarker tool in newborn infants for bone -- Bone biomarkers in gestational hypertension -- Bone biomarkers in intrauterine growth restriction -- Raman spectroscopy as a biomarker-investigative tool in bone metabolism -- Pentosidine as a biomarker for poor bone quality and elevated fracture risk -- Spine bone texture and the trabecular bone score (TBS) -- Bone biomarkers in HIV -- Bone Biomarkers Related to Osteoarthritis -- Dietary Soy Phytoestrogens and Biomarkers of Osteoporosis -- Utilisation and reference values of osteocalcin and procollagen type 1 n-propeptide -- Analysis of integrin alpha2beta1 (a2b1) expression as a biomarker of skeletal metastasis -- Circulating Sclerostin in Bone Sclerosing Disorders -- Pentraxin 3 as a bone biomarker -- Sirtuins as markers of bone disease: a focus on osteoarthritis and osteoporosis -- Tartarate resistant acid phosphatase as a biomarker of bone remodeling
    Abstract: There are many conditions that affect the skeletal system. On a worldwide basis, osteoarthritis alone affects 10%-15 percent of those over 60 years of age and in some countries more than 30-50% of postmenopausal women will have osteopenia or osteoporosis. With the increasing ageing population, maintaining skeletal health is particularly important. Fractures in the aged, for example, can lead to premature deaths. It is therefore imperative that appropriate use is made of conventional, new and emerging biomarker platforms. Biomarkers in Bone Disease embraces a holistic approach by combining information on different conditions that affect the skeletal system and the use of biomarkers. Biomarkers are described in terms of conventional, new and emerging analytes, techniques, platforms and applications. It covers the latest knowledge, trends and innovations. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry
    Pages: 186 illus., 108 illus. in color. eReference. : online resource.
    ISBN: 9789400776937
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  • 2
    Keywords: Oncology ; Oncology   ; Toxicology ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer Nature Living Reference
    Description / Table of Contents: Cardiolog -- Addictions -- Immunology -- Birth Defects -- Genetics
    Abstract: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists
    Pages: Approx. 800 p. 50 illus. : online resource.
    ISBN: 9789400777415
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  • 3
    Keywords: Medicine ; Oncology ; Toxicology ; Biomedicine ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer eBooks
    Description / Table of Contents: Biomarker for Amyotrophic Lateral Sclerosis (Motor Neurone Disease) -- Biomarkers and their applications to toxicology and toxicogenomics -- Biomarkers for Depression -- Biomarkers in Chronic Obstructive Pulmonary Disease (COPD): Current Concerns and Future Prospects -- Biomarkers in Urine and Use of Creatinine -- Biomarkers of Graft-Versus-Host Disease -- Biomarkers of Menopause -- Biomarkers of Parkinson's Disease -- Biomarkers of Vector Bites -- Biomarkers of the menopause.-℗ Chronic Heart Failure and Serum Collagen -- FABP3 as biomarkers -- Fetal Membrane Biomarkers.-℗ Flow Cytometry as Platform for Biomarker Evaluation -- Formalin-fixed paraffin-embedded tissue (FFPET) sections for biomarker discovery -- Glycomics as biomarkers -- Inflammasome Proteins as Biomarkers of Injury and Disease -- Isoprostanes as biomarkers of disease and early biological effect.-Mass spectrometry for biomarker discovery -- Micro RNA as Biomarker for Brain Injury -- MIP-1alpha as biomarker -- Natriuretic Peptides for Diagnosis, Prognosis and Management of Heart Failure -- OMICS-based approaches to biomarker discovery and challenges of subsequent validation -- Pediatric biomarkers after cardac surgery -- Pentraxin 3 as Biomarker -- Pfetin: Novel prognostic biomarker -- Plasma galectin-3 as biomarker -- S100B as a Biomarker -- Salivary amylase as a stress biomarker -- Seasonal allergic rhinitis and systems biology-oriented biomarker discovery -- Serum Heat Shock Proteins as Novel Biomarker for Heart Failure -- Urinary Biomarkers of Environmental Health: Jet Fuel -- YKL-40 as Biomarker: Focus on Cardiovascular Disease
    Abstract: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics and so on. The chapters are written by national or international experts and specialists
    Pages: XXIX, 1324 p. 204 illus., 130 illus. in color. eReference. : online resource.
    ISBN: 9789400776968
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  • 4
    Keywords: Medicine ; Oncology ; Toxicology ; Biomedicine ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer eBooks
    Abstract: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists
    Pages: XXVIII, 992 p. 180 illus., 134 illus. in color. eReference. : online resource.
    ISBN: 9789400776814
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  • 5
    Keywords: Oncology ; Oncology   ; Toxicology ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer Nature Living Reference
    Description / Table of Contents: Endocrinology -- Addictions -- Immunology -- Genetics
    Abstract: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists
    Pages: Approx. 800 p. 50 illus. : online resource.
    ISBN: 9789400777439
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  • 6
    Keywords: Oncology ; Oncology   ; Toxicology ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer Nature Living Reference
    Abstract: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists
    Pages: 800 p. 50 illus. : online resource.
    ISBN: 9789400777446
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  • 7
    Keywords: Oncology ; Oncology   ; Toxicology ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer Nature Living Reference
    Description / Table of Contents: Liver biomarkers and their applications to nutritional interventions in animal studies -- AST-to-platelet ratio index (APRI) as marker in liver disease.-Inflammatory biomarkers in ascites -- Biomarkers for hepatocellular carcinoma in East Asia -- Liver disease and acylcarnitines as mechanistic biomarkers.-Type VI Collagen: Biological Functions and its Neo-epitope as Hepatic Fibrosis Biomarker -- Fibrinogen α-chain as a serum marker of liver disease -- Monocyte chemotactic protein-1 (cytokine, receptors,and gene polymorphisms) in hepatitis -- Biomarkers for Recurrence of Hepatocellular Carcinoma.-Graft-derived cell-free DNA as a biomarker in liver transplantation -- Serum sialic acid as a biomarker in liver disease -- CD133 and EpCAM as Biomarkers in Liver Diseases -- Traditional markers in liver disease -- Biomarkers of extracellular matrix remodeling in liver diseases -- Squamous Cell Carcinoma Antigen- Immunoglobulin M (SCCA-IgM) as biomarker in liver disease: biological aspects and clinical applications -- microRNA-155 and microRNA-196b in hepatitis C virus infection -- Immunological biomarkers in liver transplantation -- Phosphatidylethanol and alcohol use in liver disease patients -- Interaction of sialyltransferases, sialidases and sialic acids in liver diseases and applications to biomarker discovery -- Biomarkers to monitor graft function following liver transplantation -- YKL-40 as a biomarker of liver diseases -- Peripheral venous, portal venous, hepatic venous, arterial and intrahepatic cytokine levels as biomarkers and functional correlations -- Histological Biomarkers of Non-Alcoholic Fatty Liver Disease -- Vascular cell adhesion molecule-1 (vcam-1) expression in liver disease -- Bilirubin as a biomarker in liver disease -- Hydroxyproline as a biomarker in liver disease -- Genetic biomarkers of paracetamol-induced acute liver failure -- PNPLA3 polymorphism and Nonalcoholic Fatty Liver Disease -- Hepascore and it's application to liver disease -- Model for End-Stage Liver Disease (MELD) Score as a Biomarker -- Biomarkers in focus: Alanine Aminotransferase -- PTX3 as a biomarker of liver disease
    Abstract: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists
    Pages: 800 p. 50 illus. : online resource.
    ISBN: 9789400777422
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  • 8
    Keywords: Medicine ; Cancer Research ; Pharmacology ; Oncology ; Biomedicine ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer eBooks
    Pages: 208 illus., 150 illus. in color. eReference. : online resource.
    ISBN: 9789400776999
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  • 9
    Keywords: Medicine ; Cancer Research ; Pharmacology ; Oncology ; Biomedicine ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer eBooks
    Description / Table of Contents: Liver biomarkers and their applications to nutritional interventions in animal studies -- AST-to-platelet ratio index (APRI) as marker in liver disease.-Inflammatory biomarkers in ascites -- Biomarkers for hepatocellular carcinoma in East Asia -- Liver disease and acylcarnitines as mechanistic biomarkers.-Type VI Collagen: Biological Functions and its Neo-epitope as Hepatic Fibrosis Biomarker -- Fibrinogen α-chain as a serum marker of liver disease -- Monocyte chemotactic protein-1 (cytokine, receptors,and gene polymorphisms) in hepatitis -- Biomarkers for Recurrence of Hepatocellular Carcinoma.-Graft-derived cell-free DNA as a biomarker in liver transplantation -- Serum sialic acid as a biomarker in liver disease -- CD133 and EpCAM as Biomarkers in Liver Diseases -- Traditional markers in liver disease -- Biomarkers of extracellular matrix remodeling in liver diseases -- Squamous Cell Carcinoma Antigen- Immunoglobulin M (SCCA-IgM) as biomarker in liver disease: biological aspects and clinical applications -- microRNA-155 and microRNA-196b in hepatitis C virus infection -- Immunological biomarkers in liver transplantation -- Phosphatidylethanol and alcohol use in liver disease patients -- Interaction of sialyltransferases, sialidases and sialic acids in liver diseases and applications to biomarker discovery -- Biomarkers to monitor graft function following liver transplantation -- YKL-40 as a biomarker of liver diseases -- Peripheral venous, portal venous, hepatic venous, arterial and intrahepatic cytokine levels as biomarkers and functional correlations -- Histological Biomarkers of Non-Alcoholic Fatty Liver Disease -- Vascular cell adhesion molecule-1 (vcam-1) expression in liver disease -- Bilirubin as a biomarker in liver disease -- Hydroxyproline as a biomarker in liver disease -- Genetic biomarkers of paracetamol-induced acute liver failure -- PNPLA3 polymorphism and Nonalcoholic Fatty Liver Disease -- Hepascore and it's application to liver disease -- Model for End-Stage Liver Disease (MELD) Score as a Biomarker -- Biomarkers in focus: Alanine Aminotransferase -- PTX3 as a biomarker of liver disease
    Abstract: There are numerous types of liver disease that may be due to toxic agents (such as alcohol or drugs), infectious agents including viruses, congenital conditions and even poor dietary patterns. It has been suggested that there are over 100 different types. As the consequences of liver failure can be devastating it is important that appropriate diagnosis and monitoring is carried out. Much of this characterisation entails the use of biological indicators, i.e biomarkers. Biomarkers in Liver Disease embraces a holistic approach by combining detailed information on different conditions that affect the liver and the use of biomarkers. Biomarkers are described in terms of conventional, new and emerging analytes, techniques, platforms and applications. It covers the latest knowledge, trends and innovations. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry
    Pages: 162 illus., 110 illus. in color. eReference. : online resource.
    ISBN: 9789400776753
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  • 10
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    Wageningen : Wageningen Academic Publishers
    Keywords: Life sciences ; Life sciences ; Life Sciences, general ; Springer eBooks
    Abstract: Emerging literature and research have currently shown that sleep, sleep disturbances, diet and nutrition are interlinked in numerous ways. For example, sleep deprivation alters food intake and snacking behaviour. On the other hand, dietary restriction and obesity alter sleep. Specific nutrients such as caffeine and alcohol also affect sleep. Furthermore, variations in these relationships differ with respect to age, gender and state of health. There is a connection between sleep and disordered nutrition as defined by conditions such as diabetes and metabolic syndrome. This book demonstrates that disruptive sleep patterns can be remedied by appropriate dietary or nutritional changes including the usage of supplements. The contribution of sleep to our daily lives is not yet fully understood, but it is clear that its impact should not be underestimated. This handbook discusses the important relationship between diet and nutrition and disruptive or abnormal sleep in the sub-clinical or clinical setting. Authorities in the field offer a wide range of scientifically sound perspectives and approaches of the link between sleep, nutrition and diet
    Pages: Approx. 500 p. 99 illus., 8 illus. in color. : digital.
    ISBN: 9789086867639
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