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  • 1
    Keywords: Medicine ; Immunology ; Toxicology ; Emerging infectious diseases ; Biochemistry ; Microbiology ; Biomedicine ; Immunology ; Microbiology ; Infectious Diseases ; Pharmacology/Toxicology ; Biochemistry, general ; Springer eBooks
    Pages: : digital
    ISBN: 9781441956323
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  • 2
    Keywords: Medicine ; Immunology ; Toxicology ; Medical virology ; Emerging infectious diseases ; Microbiology ; Biomedicine ; Immunology ; Microbiology ; Virology ; Infectious Diseases ; Pharmacology/Toxicology ; Springer eBooks
    Description / Table of Contents: Type III IFNs: Emerging Master Regulators of Immunity -- Stability of Regulatory T Cells Undermined or Endorsed by Different Type-1 Cytokines -- The Role of Il-12 and Type I Interferon in Governing the Magnitude of CD8 T Cell Responses -- Functional Diversity of Human Dendritic Cells -- Selective Dependence of Kidney Dendritic Cells on CX3CR1: Implications for Glomerulonephritis Therapy -- Mechanisms of Memory T Cell Activation and Effective Immunity -- Molecular Programming of Immunological Memory in Natural Killer Cells -- Induction of Immune Tolerance to Dietary Antigens -- The Role of p110 in the Development and Activation of B Lymphocytes -- Immune Memory and Exhaustion: Clinically Relevant Lessons from the LCMV Model
    Abstract: (none -- this book should follow the AEMB cover style template)
    Pages: VIII, 154 p. 16 illus., 15 illus. in color. : online resource.
    Edition: 1st ed. 2015.
    ISBN: 9783319157740
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  • 3
    Call number: A050:97
    Keywords: Xenopus / embryology
    Description / Table of Contents: technologies
    Pages: xiii, 568 p. : ill. (some col.)
    Edition: 2nd ed.
    ISBN: 9781617799914
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    A050:97 departmental collection or stack – please contact the library
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  • 4
    Keywords: Medicine ; Immunology ; Infectious Diseases ; Rheumatology ; Biomedicine ; Immunology ; Infectious Diseases ; Rheumatology ; Springer eBooks
    Description / Table of Contents: The appearance and diversification of receptors for IgM during vertebrate evolution. -- Authentic IgM Fc Receptor (FcμR) -- FCRLA - A resident endoplasmic reticulum protein that associates with multiple immunoglobulin isotypes in B lineage cells -- Specific IgM and regulation of antibody responses -- Role of Natural IgM autoantibodies (IgM- NAA) and IgM anti-leucocyte antibodies (IgM-ALA) in regulating inflammation
    Abstract: This volume reviews the current state of research on the IgM antibody and its multiple receptors and binding proteins. Interactions of the IgM ligands with these molecules are important for protection against infections as a first line of defense, as well as for regulation of immune responses to pathogens and self-antigens. The book includes up-to-date information on: (i) the phylogeny of three IgM-binding receptors [polymeric Ig receptor (pIgR), Fc receptor for both IgA and IgM (Fcα/µR), and Fc receptor for IgM only (FcµR)]; (ii) the lymphocyte-restricted distribution and unique ligand-binding activity of FcµR; (iii) the definition and potential function of Fc receptor-like molecule A (FCRLA) as a resident endoplasmic reticulum protein that binds IgM, but also IgG and IgA; (iv) IgM antibody-mediated enhancement of humoral immune responses, highlighting the importance of complement and its receptors, (v) the numerous important roles of IgM natural antibodies in regulation of inflammation. It is an invaluable resource for researchers and clinicians alike
    Pages: IX, 117 p. 30 illus., 15 illus. in color. : online resource.
    ISBN: 9783319645261
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  • 5
    Keywords: Medicine ; Human Physiology ; Respiratory organs / Diseases ; Sports Medicine ; Biomedicine ; Human Physiology ; Pneumology/Respiratory System ; Sports Medicine ; Springer eBooks
    Description / Table of Contents: Chapter 1: Introduction and history -- Chapter 2: MIGET: Basic Physiological Principles -- Chapter 3: Mathematical Underpinnings -- Chapter 4: Strengths and Limitations from a Mathematical Perspective -- Chapter 5: Physiological Information Content of MIGET -- Chapter 6: MIGET: Practical Aspect -- chapter 7: Review of the MIGET Literature
    Abstract: This is the first book to bring together the history, theory, mathematical approach, measurement details and limitations of the Multiple Inert Gas Elimination Technique (MIGET) and a summary of the global literature on its application in health and disease over the last 40 years. Up to the early 1970's, and despite substantial research carried out by leaders in respiratory physiology, it was not possible to measure the most important and most complex component of gas exchange in the lung: ventilation/perfusion (VA/Q) heterogeneity. Building on that earlier research, MIGET was developed to overcome this large gap in our understanding of the most important function of the lung. Just as CT and MRI make use of multiple, simultaneous imaging views to reconstruct the underlying anatomy spatially, MIGET uses the simultaneous exchange of six inert gases with differing blood solubility to reconstruct the functional distribution of VA/Q ratios. While the basic physiological principle of MIGET is straightforward, using inert gas exchange data to construct the VA/Q distribution requires complicated mathematics along with the ability to simultaneously measure the exchange of six foreign gases present in just parts per million or less. This unique book is a valuable resource for anyone interested in how the lung works
    Pages: XIII, 329 p. 56 illus., 24 illus. in color. : online resource.
    ISBN: 9781493974412
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  • 6
    Unknown
    New York, NY : Springer Science+Business Media, LLC
    Keywords: Medicine ; Oncology ; Human Genetics ; Toxicology ; Biomedicine ; Cancer Research ; Human Genetics ; Pharmacology/Toxicology ; Springer eBooks
    Pages: : digital
    ISBN: 9781441910752
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  • 7
    Unknown
    Oxford : Oxford University Press
    Call number: E020:45
    Keywords: Solid-phase synthesis ; Peptides / Synthesis
    Pages: xxiv, 346 p. : ill.
    Edition: Reprinted
    ISBN: 0199637245
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    E020:45 departmental collection or stack – please contact the library
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  • 8
    Unknown
    Philadelphia, PA : Churchill Livingstone/Elsevier
    Call number: QH432:38(14)
    Keywords: Medical genetics ; Genetics, Medical ; Genetic Diseases, Inborn
    Notes: For online access to this volume please contact the library staff in room D124 (phone 3661, e-mail: http://www.dkfz.de/de/zbib/mitarbeiter/kontakt/fernleihe.php
    Pages: xiii, 445p. : ill.
    Edition: 14th ed.
    ISBN: 9780702040436
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    QH432:38(14) available
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  • 9
    Keywords: Medicine ; Immunology ; Toxicology ; Medical virology ; Emerging infectious diseases ; Microbiology ; Biomedicine ; Immunology ; Microbiology ; Virology ; Infectious Diseases ; Pharmacology/Toxicology ; Springer eBooks
    Description / Table of Contents: €‹Ís Transcription the Dominant Force during Dynamic Changes in Gene Expression? -- MicroRNAs: Key Components of Immune Regulation -- KIR/HLA: Genetic Clues for a Role of NK cells in the Control of HIV -- Natural Killer cell Licensing during Viral Infection -- Bridging Innate NK cell Functions with Adaptive Immunity -- Control of Innate Immunity by Memory CD4 T cells -- Strategies and Implications for Prime-Boost Vaccinations to Generate Memory CD8 T Cells -- Blimp1: Driving Terminal Differentiation to a T -- A new Role for Myeloid HO-1 in the Innate to Adaptive Crosstalk and Immune Homeostasis -- Impact of Differential Glycosylation on IgG Activity -- Murine Model of Chronic Respiratory Inflammation -- Incorporation of Innate Immune Effector Mechanisms in the Formulation of a Vaccine Against HIV-1 -- Influenza Vaccines: What do we Want and How can we Get it?.́€&#x2039
    Abstract: This volume presents a collection of reviews derived from work presented at the Aegean Conference: ́€œ4th℗ Crossroads between innate and adaptive immunitý€.℗ This meeting was the fourth℗ in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference ́€œCrossroads between Innate and Adaptive Immunitý€ brought together leading international scientists and experts to address critical areas of Innate and Adaptive immunity something necessary for the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive immunity. The conference had limited participation and a scientific and social program that maximized scientific interchange through lecture presentations, poster sessions and informal discussions
    Pages: : digital.
    ISBN: 9781461462170
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  • 10
    Keywords: Medicine ; Neurosciences ; Psychopharmacology ; Behavioral Therapy ; Behavioral Sciences ; Biomedicine ; Neurosciences ; Psychopharmacology ; Behavioral Therapy ; Behavioral Sciences ; Springer eBooks
    Description / Table of Contents: Part 1 -- THE NEUROBIOLOGY OF COMPONENTS OF MOTIVATIONAL DRIVE -- Regulation of the Motivation to Eat -- Sexual Motivation Opposed by the Influences of Stress -- Motivational Forces Driving Social Behaviours -- The Roles of Wanting and Liking in Motivating Behaviour, Including Gambling, Food and Drug Addiction. Circadian Regulation of Motivated Behaviour -- How Negative Forces Influence Motivations Part 2 -- NEURAL MEASURES AND CORRELATES OF MOTIVATION SIGNALS AND COMPUTATIONS -- Neural Computations of Postive and Negative Reward Value -- The Dopaminergic Regulation of Motivated Behaviour -- Neural Modulators other than Dopamine that Regulate Motivated Behaviours -- Neural Correlates of Motivation Signals in Humans -- Motivational Forces in Decision Making Processes -- Part 3 -- APATHY AND PATHOLOGICAL DEFICITS IN MOTIVATION -- The Identification of Phenotypes and Biomarkers in Depression -- Defining Motivation Deficits in Schizophrenia and Relating them to Clinical Symptoms -- Dissecting the Behavioural components of deficits in motivation in Patients with Schizophrenia -- How Deficits in Motivation are Similar and Different in Depression and Schizophrenia -- Modeling Motivation Deficits in Rodents -- Part 4 -- ADDICTION AND THE APTHOLOGICAL MISDIRECTION OF MOTIVATED BEHAVIOUR -- Motivation in Overdrive: Substance Abuse Disorder -- Insight into Gambling motivation from Animal Models -- Part 5 -- DEVELOPMENTS IN TREATMENTS FOR MOTIVATION PATHOLOGIES -- The Role of Motivation in Schizophrenia Cognitive Remediation -- The Impact of Regulating Focus on Motivated Behaviour -- Insights into Gambling Motivation from Animal Models -- Exploring Pharmacological Agents in Animal Models
    Abstract: This volume covers the current status of research in the neurobiology of motivated behaviors in humans and other animals in healthy condition. This includes consideration of the psychological processes that drive motivated behavior and the anatomical, electrophysiological and neurochemical mechanisms which drive these processes and regulate behavioural output. The volume also includes chapters on pathological disturbances in motivation including apathy, or motivational deficit as well as addictions, the pathological misdirection of motivated behavior. As with the chapters on healthy motivational processes, the chapters on disease provide a comprehensive up to date review of the neurobiological abnormalities that underlie motivation, as determined by studies of patient populations as well as animal models of disease. The book closes with a section on recent developments in treatments for motivational disorders
    Pages: XIV, 587 p. 80 illus., 60 illus. in color. : online resource.
    Edition: 1st ed. 2016.
    ISBN: 9783319269351
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