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  • 1
    facet.materialart.
    Unknown
    German Medical Science; Düsseldorf, Köln
    In:  Kooperative Versorgung - Vernetzte Forschung - Ubiquitäre Information; 49. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 19. Jahrestagung der Schweizerischen Gesellschaft für Medizinische Informatik (SGMI) und Jahrestagung 2004 des Arbeitskreises Medizinische Informatik (ÖAKMI) der Österreichischen Computer Gesellschaft (OCG) und der Österreichischen Gesellschaft für Biomedizinische Technik (ÖGBMT); 20040926-20040930; Innsbruck; DOC04gmds057 /20040914/
    Publication Date: 2004-09-14
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 2
    facet.materialart.
    Unknown
    German Medical Science; Düsseldorf, Köln
    In:  68. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie, 90. Tagung der Deutschen Gesellschaft für Orthopädie und Orthopädische Chirurgie und 45. Tagung des Berufsverbandes der Fachärzte für Orthopädie; 20041019-20041023; Berlin; DOC04dguQ1-498 /20041019/
    Publication Date: 2004-10-20
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 3
    ISSN: 1432-0789
    Keywords: Earthworm burrows ; X-ray computed tomography ; three-dimensional visualization ; Allolobophora caliginosa ; Octolasium cyaneum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Earthworm burrows of endogeic species (Allolobophora caliginosa, Octolasium cyaneum) in artificially packed soil columns were examined using X-ray computed tomography. By means of digital image processing, it was possible to reconstruct and visualize the burrow system in three dimensions. The reconstruction revealed morphological features of the burrows which were not obvious from two-dimensional section images.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0738
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The pharmacokinetics of Tl+ were studied in 9 patients who underwent myocardial scintigraphy with201Tl+. The time course of the201Tl+ concentration fitted to an open two-compartment model. The following values were calculated:k 12=0.164±0.025 min−1,k 21=0.011 ± 0.004 min−1,k 10=0.005±0.004 min−1,t 1/2(κ1)=3.92±0.54 min, t1/2(λ2)= 3108±896 min,CL=0.08±0.03 l/min,V 1=0.26±0.13 I/kg,V z =4.36 ± 0.65 l/kg,V ss =4.23±0.67 l/kg. Using previously published dialysance values the influence of hemodialysis on Tl+ elimination was calculated. Hemodialysis in Tl+ intoxications should be moderately effective.
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  • 5
    ISSN: 1619-7089
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1619-7089
    Keywords: COST ; Data base ; Knowledge-based systems ; Network ; Quality control ; Software ; Software phantom
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Since the 1984 Congress of the Society of Nuclear Medicine-Europe in Helsinki, the “Task Group for European Nuclear Medicine Software Cooperation”, which became the “Joint ENMS/SNME Nuclear Medicine Software Task Group” in London in 1985, has focused attention on establishing a new COST project (European Cooperation in the Field of Scientific and Technical Research) (COST 1981) in the field of nuclear medicine Software. On 20 March 1986, the mandate was finally approved officially by the COST Committee of Senior Officials in Brussels (see Editorial in this issue). The problems, content, and objectives of specific items and ideas regarding NM software that have been publicized at the European level are dealt with here. The reader actively interested in NM software is encouraged to participate in the COST framework and forum, in order to avoid duplication of effort and to utilize resources more efficiently by coordinating activities in nuclear medicine in Europe.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nuclear medicine 5 (1980), S. 175-184 
    ISSN: 1619-7089
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A general view of nuclear medicine's present status and future trends in Europe is given. Nuclear medicine procedures, radiopharmaceuticals, annual examinations, equipment, quality assurance, management, and number of installations of gamma cameras, and computer systems in Europe are considered. Market trends are given. The role of nuclear medicine computer systems, hardware and software, is discussed. The situation of nuclear medicine in Europe, especially in the Federal Republic of Germany (FRG) with regard to economic and medical factors, is investigated.
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  • 8
    ISSN: 1619-7089
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A patient-specific three-dimensional rotational ellipsoidal shell was reconstructed from planar myocardial scintigrams. This model was homogeneously filled with radioactivity (‘ideal’) and then projected onto the same planes as the actual scintigrams, including the absorption of heart and background. After normalization and inhomogenous background correction, the actual and ‘ideal’ images were compared in order to quantify the myocardial, ischemic and infarcted volumes (difference quantitation). 201Tl defects appeared as hot spots. The a priori three-dimensional model was cut into 14 segments by six planes. Tomographic sectional views in any desired plane made possible the identification of the 14 spatial myocardial segments on slice images for difference quantitation. The orientation of the long axis of the left heart responsible for different inseparable overprojections of segments was accounted for. The mathematics of segmentation and reconstructive three-dimensional modelling is described. Computed examples are given. A total of 624 201Tl scintigrams from 78 patients were analysed according to this method. The results obtained for the myocardial, ischemic and infarcted volumes, the orientation of the left heart's axis in the thorax and the identification of spatial myocardial segments on projected and tomographic images, as well as the global myocardial and background kinetics of 201Tl are discussed. The procedure of reference modelling and diffrence quantitation might also be useful in other imaging modalities, such as emission-computed tomography, single-photon emission computed tomography, computed tomography or nuclear magnetic resonance.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 188 (1966), S. 308-330 
    ISSN: 1432-1459
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 1. Im Nervus saphenus von geschlechtsreifen Kaninchen wurde unter aseptischen Bedingungen eine intraneurale Catgutnaht angelegt. Im Läsionsbereich ergibt sich nach 21 Tagen unter Bildung eines Resorptionsgranuloms ein Zustand, der als Modell eines Engpaßsyndroms mit ausgiebiger endoneuraler Beteiligung dienen kann. 2. Morphologisch findet sich im Läsionsbereich über eine mittlere Distanz von 2 mm eine nahezu vollständige Demyelinisierung des Nerven. Distal vom Granulombereich sind dagegen markhaltige Nervenfasern aller Kaliber erhalten. 3. Die Markscheidenveränderungen im Läsionsbereich zeigen den Typ der segmentalen Fasererkrankung mit vollständiger Demyelinisierung in unmittelbarer Nachbarschaft des Catgutfadens. Proximal und distal schließen sich kurze Strecken mit intercalären Segmenten und verbreiterten Ranvierschen Knoten an. Elektronenoptisch weisen die markarmen Nervenfasern im Läsionsbereich rosenkranzähnliche, spindelförmige Anschwellungen auf. 4. Nur ein Teil der Nervenfasern des distalen Abschnitts unterliegt der Wallerschen Degeneration. Sie beruht nicht nur auf dem Trauma durch das Anlegen der Catgutnaht, sondern ist in beträchtlichem Maße auch Folge der endoneuralen Fremdkörperreaktion. 5. Die Funktion eines Teils der Fasern ist im Läsionsbereich und im distalen Abschnitt vollständig ausgefallen. Der vollständige Funktionsausfall ist in den A-Fasern deutlicher als in den B (Aδ)-Fasern, in diesen auffälliger als in den C-Fasern. 6. Für einen weiteren Teil der Fasern besteht im Läsionsbereich selbst ein lokalisierter Block. Hiervon sind die C-Fasern stärker als die B-Fasern, diese stärker als die A-Fasern betroffen. 7. Die Reduktion der Leitungsgeschwindigkeit im Läsionsbereich betrifft die noch funktionsfähigen A-Fasern stärker als die B-Fasern. Die C-Fasern lassen keine sichere Verminderung der Leitungsgeschwindigkeit erkennen. 8. Im Läsionsbereich findet sich in den funktionsfähigen Aα- und den Aβ-Fasern eine Erhöhung der relativen Refraktärzeit. Proximal und distal vom Läsionsbereich ist die relative Refraktärzeit gegenüber den Kontrollen unverändert. 9. Die Beziehungen zwischen morphologischem Befund und Funktionsstörungen werden diskutiert. Es wird angenommen, daß der lokalisierte Block ebenso wie der Funktionsausfall infolge Wallerscher Degeneration auf einer axonalen Schädigung beruht und daß diese beiden Funktionsstörungen nicht pathogenetisch, sondern nur graduell voneinander unterschieden sind. Dagegen wird die Reduktion der Leitungsgeschwindigkeit der markhaltigen Fasern im Läsionsbereich auf die Markscheidenveränderungen zurückgeführt. Die Befunde sprechen dafür, daß in vollständig demyelinisierten Nervenfaserabschnitten die saltatorische Erregungsleitung durch den kontinuierlichen Leitungsmodus ersetzt ist.
    Notes: Summary 1. Intraneural catgut sutures were placed into saphenous nerves of adult rabbits. At the site of the lesion a resorption granuloma is formed within 21 days resembling a narrow-passage syndrome with extensive involvement of endoneural structures. 2. There is an almost complete demyelination of the nerve over a distance of 2 mm at the site of the lesion. In contrast, fibres of all calibres remain intact distal to the lesion. 3. In the affected nerve area adjacent to the catgut suture changes of the myelin sheath are of the type of segmental demyelination. There are short tracts disclosing “segmentes intercalaires” and widened Ranvier nodes proximal and distal to this area. Electron microscopy reveals unmyelinated C-fibres as swollen spindle-shaped structures at the site of the lesion. 4. Only part of the nerve fibres distal to the lesion undergo Wallerian degeneration. Wallerian degeneration in this case is due not only to the primary injury by the catgut suture but also to the endoneural foreign body reaction. 5. Because of the Wallerian degeneration, the function of some nerve fibres is completely destroyed at the site of the lesion and distal to it. This functional lesion is more pronounced with A-fibres than with B (Aδ)-fibres. C-fibres are least affected. 6. Other nerve fibres are only blocked at the site of the lesion. This localized blocking is more pronounced with C-fibres than with B-fibres and least pronounced with A-fibres. 7. The conduction velocity in the area of the lesion is markedly reduced in A-fibres, to a lesser extent in B-fibres. No reduction was found in C-fibres. 8. The relative refractory period is prolonged in the Aα- and Aβ-fibres. This effect is seen only within the area of the lesion. There was no deviation from controls in portions of the nerve proximal and distal to the lesion. 9. The relationship between morphological and electrophysiological findings are discussed. It is assumed that both the localized block and the complete loss of function in the course of Wallerian degeneration are due to the same axonal injury. These functional disturbances differ only with respect to their extent but not with respect to their pathogenesis. — On the other hand, the reduced conduction velocity at the site of the lesion is attributed to the damage of the myelin sheath. The data suggest that saltatory conduction is replaced by a continuous mode of conduction in completely demyelinated portions of nerve fibres.
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  • 10
    ISSN: 1435-2451
    Keywords: Iodine-induced thyrotoxicosis ; Hyperthyroidism ; Thyroidectomy ; Graves' disease ; Jodinduzierte Hyperthyreose ; Jodkontamination ; Hyperthyreose ; Thyreoidektomie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Klinischer Verlauf, Operationsindikation und Behandlungsergebnisse bei 12 Patienten mit jodinduzierter Hyperthyreose werden vorgestellt. Alle Patienten wurden initial thyreostatisch behandelt, 2 Patientinnen zusätzlich mit Plasmapherese. Als frühzeitige operative Behandlung werden folgende Verfahren empfohlen: a) Enucleation beim solitären autonomen Adenom oder Hemithyreoidektomie bei großen oder einseitig multiplen autonomen Knoten, b) subtotale Resektion beidseits bei der toxischen multinoduldren Knotenstruma oder, bevorzugt, Hemithyreoidektomie und kontralateral subtotale Resektion, c) ,„near-total” Thyreoidektomie bei der Immunthyreopathie M. Basedow. Der postoperative Verlauf war bei allen 12 Patienten komplikationslos.
    Notes: Summary The clinical course, indications for surgical treatment, and results of treatment in 12 patients with iodine-induced thyrotoxicosis are reported. All patients were treated initially with antithyroid drugs, in two females, additional plasmapheresis was performed. The following early surgical treatment is recommended: (a) enucleation of solitary autonomous adenomas or unilateral lobectomy if there are large or multiple unilateral autonomous nodules; (b) subtotal bilateral lobectomy in toxic multinodular goiter or, preferably, unilateral lobectomy, combined with subtotal resection of the contralateral lobe; (c) “near-total” thyroidectomy in Graves' disease. The postoperative course in all patients was uneventful.
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