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  • 1
    Call number: C060:170
    Keywords: Proportional Hazards Models ; Survival Analysis
    Description / Table of Contents: The special nature of survival data -- Cox regression model -- Measuring the predictive value of a Cox model -- Calibration and revision of Cox models -- Mechanisms explaining violation of the Cox model -- Non-proportional hazards models -- Dealing with non-proportional hazards -- Dynamic predictions using biomarkers -- Dynamic prediction in multi-state models -- Dynamic prediction in chronic disease -- Penalized Cox models -- Dynamic prediction based on genomic data
    Abstract: "In the last twenty years, dynamic prediction models have been extensively used to monitor patient prognosis in survival analysis. Written by one of the pioneers in the area, this book synthesizes these developments in a unified framework. It covers a range of models, including prognostic and dynamic prediction of survival using genomic data and time-dependent information. The text includes numerous examples using real data that is taken from the authors collaborative research. R programs are provided for implementing the methods"--Provided by publisher
    Pages: xvi, 234 p.
    ISBN: 9781439835333
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    C060:170 departmental collection or stack – please contact the library
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    ISSN: 0304-4165
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    ISSN: 0304-4165
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0304-4165
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0630
    Keywords: PACS: 36; 79.60; 81.40
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: 60 with trains of picosecond infrared (IR) pulses, tuned over the 8–15 μm range, is studied. At some specific wavelengths, white-light emission as well as ejection of ionic species from the solid is observed. The spectral characteristics of the white-light emission resemble those of a black body. The mass distribution of the ejected ionic species shows substantial amounts of C60 coalescence products. Unexpectedly, all these processes only occur at wavelengths where solid C60 is relatively transparent. No white-light emission nor ejection of ionic species is observed when being resonant with an IR-allowed transition of C60. It is concluded that regular C60 is not the chromophore for the observed processes, and that sequential absorption of single photons by a strong absorber that is dilute in the crystal takes place. Plausible chromophores are sites that are intercalated with alkali metals. Accumulation of energy at these sites leads to fullerene coalescence in the solid, ion ejection, and white-light emission, ultimately resulting in the destruction of the C60 molecules.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 22 (1995), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: SUMMARY One hundred and seventy-three IMZ two-stage implants have been clinically and radiologically evaluated for a 5 year period. The implants were placed in the anterior region of the maxillae of 81 patients to replace lost incisors, cuspids and bicuspids. The implants were placed 3 months or later after loss of natural anterior teeth when the resorption was already in an advanced stage. The implants used in this study consisted of titanium coated with hydroxylapatite. The prosthetic restorations placed on the implants consisted of fixed or removable partial dentures and single crowns. The cumulative percentage for implant survival after 3 years, with a mean follow-up of 33.5 (s.d. 17.8) months was 96.1%. Although the prosthetic restorations aesthetically often were a compromise they did prove highly satisfactory to both patients and dentists.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary A total of 214 radiographs of 76 Tubingen implants placed in the anterior region of the maxillae of 56 patients were evaluated by two observers. The first radiographs were taken after implant placement (n = 76). The second set of radiographs were taken during months 13–23 (n =53), the third during the months 24–35 (n = 28), the fourth during months 36–47 (n = 15), the fifth during months 48–59 (n = 18) and the sixth during months 60–72 (n = 20). Only four radiographs were available after longer periods, namely the eight and the ten year of function. The two observers together classified the marginal bone height (mesial and distal) as 0 (no resorption) or 1–5 in steps of 2–5 mm resorption. A score of 1 represents marginal bone resorption less than 2–5 mm, 2 from 2–5 mm to 5 nun, 3 from 5 to 7–5 mm, 4 from 7–5 to 10 mm and 5 more than 10 mm loss of marginal bone height. Thirty-six implants scored marginal bone height of 0 or 1. Twenty-two implants scored not higher than 2. Eight implants scored bone loss up to 3, four up to 4 and one up to 5. Five implants were lost.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary One hundred and seventy-three IMZ″-implants in 81 patients, placed in the anterior region of the maxilla, were evaluated radiographically by two observers. Radiographs were evaluated at three intervals, namely at the time of implant placement, the time of prosthetic restoration and at the latest available radiograph, on average 2 1/2 years after implant placement. In this study marginal bone height and the type of radiolucency adjacent to the implant were determined. Both observers were able to classify the marginal bone height (mesial and distal) and the distinctive type of resorptive defects to an acceptable level of agreement, with Cohen's kappa ranging between 0.48 and 0.69. It was found that, at the most recent visit to the clinic, angular-shaped resorptive defects are found mesially and/or distally of the implants at approximately 25% of the implants. At this stage 20.7% of the mesial implant sites and 27.9% of the distal implant sites show marginal bone heights less than three-quarters of the implant length. These findings do not fully underscore and sometimes even contradict the clinical observations which were considered highly satisfactory.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of the study was to evaluate the material behaviour and nature of implant-supported superstructures in function. A total of 37 overdentures, 26 fixed partial and 13 fixed full dentures with a mean lifetime of 40 months were clinically evaluated in relation to damage, occlusion and articulation, parafunction, retentive devices, hygiene and speech problems. In general 70% of all superstructures were damaged. Fixed partial dentures were significantly less damaged than overdentures and fixed full dentures (P〈0·001). A significant high percentage of newly gained parafunction was found (P〈0·05).
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary The influence of a three-layered flexible coating of Polyactive® on bone stress distribution was investigated by three-dimensional finite element models of mandibular bone, in which a titanium implant (coated or uncoated) was located. Poly-active® is a system of poly(ethylene oxide) poly(butylene terephthalate) segmented co-polymers with bone-bonding capacity. In the case of sagittal and transversal loading, the use of a Polyactive® coating reduced both the minimum principal stress in the bone and the compressive radial stress at the bone-implant interface. However, it raised the maximum principal and the tensile radial stress. In the case of vertical loading, the application of a flexible coating reduced the compressive radial stress at the bone-implant interface around the neck of the implant by a factor of 6.6 and the tensile radial stress by a factor of 3.6. Variations in composition and thickness of the coating did not affect the results significantly.
    Type of Medium: Electronic Resource
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