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  • 1
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA); 20160914-20160917; Bern; DOCP3-436 /20160905/
    Publication Date: 2016-09-05
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 2
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2015); 20151020-20151023; Berlin; DOCWI37-1086 /20151005/
    Publication Date: 2015-10-06
    Keywords: Strahlenschutz ; Roentgen ; Compliance ; Wissen ; Operationssaal ; Fragebogen ; ddc: 610
    Language: German
    Type: conferenceObject
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  • 3
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2015); 20151020-20151023; Berlin; DOCWI46-1211 /20151005/
    Publication Date: 2015-10-06
    Keywords: pediatric deformity correction ; guided growth ; growth modulation ; adverse events ; Eight Plate ; ddc: 610
    Language: English
    Type: conferenceObject
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  • 4
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    German Medical Science; Düsseldorf, Köln
    In:  122. Kongress der Deutschen Gesellschaft für Chirurgie; 20050405-20050408; München; DOC05dgch2430 /20050615/
    Publication Date: 2005-06-16
    Keywords: ddc: 610
    Language: German
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  • 5
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The Escherichia coli fructose repressor, FruR, is known to regulate expression of several genes concerned with carbon utilization. Using a previously derived consensus sequence for FruR binding, additional potential operators were identified and tested for FruR binding in DNA band migration retardation assays. Operators in the control regions of operons concerned with carbon metabolism bound FruR, while those in operons not concerned with carbon metabolism did not. In vivo assays with transcriptional lacZ fusions showed that FruR controls the expression of FruR operator-containing genes encoding key enzymes of virtually every major pathway of carbon metabolism. Moreover, a fruR null mutation altered the rates of utilization of at least 36 carbon sources. In general, oxidation rates for glycolytic substances were enhanced while those for gluconeogenic substances were depressed. Alignment of FruR operators revealed that the consensus sequence for FruR binding is the same for operons that are activated and repressed by FruR and permitted formulation of a revised FruR-binding consensus sequence. The reported observations indicate that FruR modulates the direction of carbon flow by transcriptional activation of genes encoding enzymes concerned with oxidative and gluconeogenic carbon flow and by repression of those concerned with fermentative carbon flow.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-072X
    Keywords: Coding regions ; Codon frequency table ; IS-like elements ; Nitrogen fixation ; Nodulation ; Repeated sequence ; Bradyrhizobium japonicum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract To date, the sequences of 45 Bradyrhizobium japonicum genes are known. This provides sufficient information to determine their codon usage and G+C content. Surprisingly, B. japonicum nodulation and NifA-regulated genes were found to have a less biased codon usage and a lower G+C content than genes not belonging to these two groups. Thus, the coding regions of nodulation genes and NifA-regulated genes could hardly be identified in codon preference plots whereas this was not difficult with other genes. The codon frequency table of the highly biased genes was used in a codon preference plot to analyze the RSRjα9 sequence which is an insertion sequence (IS)-like element. The plot helped identify a new open reading frame (ORF355) that escaped previous detection because of two sequencing errors. These were now corrected. The deduced gene product of ORF355 in RSRjα9 showed extensive similarity to a putative protein encoded by an ORF in the T-DNA of Agrobacterium rhizogenes. The DNA sequences bordering both ORFs showed inverted repeats and potential target site duplications which supported the assumption that they were IS-like elements.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Immunogenetics 1 (1974), S. 507-510 
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Immunogenetics 2 (1975), S. 561-567 
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The injection of F1 hybrid spleen cells into lethally irradiated parental strain recipients resulted in the formation of antisera containing antireceptor antibody but no alloantibody activity. The results demonstrated radioresistance of the immunogenic property of T-cell receptors for alloantigens and confirmed earlier conclusions on the origin of antireceptor antibody-forming cell populations. The system employed invited investigation into a possible cooperation between F1 B and F1 T lymphocytes in the formation of anti-RS antibodies in unirradiated and in lethally irradiated parental strain hosts. In the absence of F1 T cells, F1 B cells were incapable of forming these antibodies and vice versa. Semiallogeneic synergism in which parental T cells were to cooperate with F1B cells could not be observed. Addition to F1B inoculum of T lymphocytes from syngeneic, from allogeneic, and from semiallogeneic sources before injection into parental recipients also gave results that excluded all but a syngeneic T-B cell collaboration. The production of antibodies to parental T-cell receptors, therefore, seems to require recognition of allogeneic receptor by both T and B lymphocytes.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 336 (1962), S. 77-86 
    ISSN: 1432-2307
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In 100 autopsies the occurence of arteriosclerotic changes in the arteries of the femur are studied; these arteries are compared with others of the body. By the end of the second decade of life the arteria nutrica femoris and its branches may show beginning arteriosclerotic changes, such as deposition of fat and calcium, and intimal fibrosis. Furthermore, these changes are more severe about a decade earlier than in other similar arteries of the body. The changes appear to be more intense in men than in women. They increase with age. In addition, in hypertensive persons the severity of damage to the vascular wall is greater. Reference is made to especially severe forms; in a case of thyrotoxicosis, and also in arthritis urica, and above all in senile osteoporosis.
    Notes: Zusammenfassung Bei 100 Sektionsfällen wurden die Arterien des Femurknochens auf das Vorkommen von arteriosklerotischen Veränderungen untersucht und mit den anderen Arterien verglichen. Die Arteria nutricia femoris und ihre Zweige können schon vom Ende des zweiten Lebensjahrzehnts an den Beginn arteriosklerotischer Veränderungen im Sinne von Fett- und Kalkablagerungen, aber auch von Intimafibrose zeigen. Diese Veränderungen erreichen auch etwa ein Dezennium früher als an den übrigen Körperarterien gleicher Art schwerere Grade. Die Intensität der Veränderungen erscheint bei Männern etwas höher als bei Frauen, sie nimmt mit steigendem Alter zu. Auch bei Hypertonikern ist die Intensität der Gefäßwandschädigungen etwas größer. Auf besonders schwere Formen in einem Fall von Thyreotoxikose, einem Fall von Arthritis urica und bei der senilen Osteoporose wird hingewiesen.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1420-9071
    Keywords: Bottleneck theory ; calorimetry ; chemostat ; Crabtree effect ; glucose effect ; S. cerevisiae ; yeast metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The growth physiology ofSaccharomyces cerevisiae strains H1022 and Whi2+ has been studied in aerobic batch and continuous (chemostat) cultures. Results from the measurement of biomass and medium components (off-line) together with oxygen, carbon dioxide and heat measurements (on-line) have been used in an attempt to explore the existence of ‘overflow’ or ‘bottleneck’ metabolism as opposed to catabolite repression (Crabtree effect) in these strains. Chemostat experiments indicated that specific oxygen uptake rate (q o 2) was linearly related to the dilution rate (D) at values below the critical dilution rate (D crit ), becoming constant aboveD crit , which is in agreement with the bottleneck theory. However, batch culture experiments indicated negligible oxygen consumption during the initial glucose growth phase, the culture exhibiting purely anaerobic metabolism. The bottleneck theory would propose thatq O 2, has a constant (maximum) value under these conditions. The results presented here suggest that while the bottleneck theory can be adequately used to describe chemostat growth ofS. cerevisiae, some other control mechanism must be operating under conditions of high glucose concentrations, such as those initially prevailing in the batch culture experiments.
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