Springer Online Journal Archives 1860-2000
Summary For a histochemical study of ubiquinones in newborn and adult mice, the hydroquinone-tetrazolium-reductase reaction was performed in cryostat serial sections of the central cerebellar nuclei. This enzyme was studied in various structures at different stages of postnatal development. The present study shows that in the central nuclei the ubiquinones display less activity during development than in the adult mouse. The histochemical maturation is slow as compared with Purkinje cells, the rest of the molecular layer, the motor nuclei of the brain stem and the anterior horns of the medulla. The relationship of these histochemical findings and the metabolic significance of changes in the patterns of ubiquinones is discussed.
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