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  • 1
    ISSN: 0949-2925
    Keywords: Schlüsselwörter: Workstation/Server ; Datenbanken ; Objektorientierung ; Ingenieuranwendungen ; Verarbeitungskonzept ; Key words: Workstation/server ; databases ; object orientation ; engineering applications ; processing model
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Abstract. Engineering and design systems typically employ their engineering and design tools in a workstation/server environment. Usually it is the task of the database server to manage the persistent design data, whereas the tools run at the workstation site. Due to efficiency considerations it is overly important that the application's current design data are cached in the main memory at the workstation, thereby exploiting near-by-application locality. In this paper, we introduce some important workstation/server architectures and we discuss their suitability for engineering applications that build upon database system. The discussion is focussed on data extraction from the server, data representation and processing at the workstation, integration of committed design data into the global database as well as on synchronization and recovery issues. Furthermore, the processing model is being detailled whilst refining the basic architectures. Our investigations reveal that there is no single optimal architecture; in contrast, the specific characteristics of the application at hand determine the suitability of the various architectures. Therefore, we give some decision guidelines on how to choose the best system architecture for a given application scenario.
    Notes: Zusammenfassung. Werkzeugorientierte Verarbeitung in datenbankbasierten Ingenieursystemen geschieht typischerweise in einer Workstation/Server-Umgebung. Dabei sind die werkzeugrelevanten Entwurfsdaten für die Dauer der Verarbeitung aus Effizienzgründen (Referenzlokalität) im Hauptspeicher der Workstation zu puffern. Die Rolle der langfristigen Datenspeicherung sowie der Datenversorgung der beteiligten Workstations übernimmt der Datenbank-Server. In diesem Artikel werden verschiedene Workstation/Server-Architekturen vorgestellt und hinsichtlich ihrer Tauglichkeit für datenbankbasierte Ingenieuranwendungen bewertet. Im Brennpunkt dieser Betrachtungen stehen Datenextraktion, Datenbereitstellung und -verarbeitung sowie Integration der geänderten Daten, Datensicherung und Synchronisation. Das Verarbeitungsmodell haben wir detailliert und dabei wichtige Merkmale herausgearbeitet sowie die Grundformen bekannter Architekturen verfeinert. Zudem wird eine Entscheidungshilfe zur Auswahl der geeigneten Systemarchitektur für eine gegebene Anwendung erarbeitet. Unsere Untersuchungen zeigen, daß keine global optimale Architektur existiert und daß für die Bewertung eines Ansatzes die spezifischen Charakteristika der Zielanwendung entscheidend sind. Hier ist insbesondere ausschlaggebend, ob deskriptiv formulierte Datenanforderungen und vorab bekannte Verarbeitungskontexte der Anwendung effizient und auf ihre Bedürfnisse zugeschnitten verfügbar gemacht werden können.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0949-2925
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0827
    Keywords: Proteolipid ; Phospholipids ; Vitamin D ; Calcification ; Cartilage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Previous studies have shown thatin vitro calcification of chick epiphyseal cartilage matrix vesicles is proteolipid-dependent. The purpose of this research is to examine the role of proteolipid in cartilage calcificationin vivo by comparing the proteolipid concentration of normal and vitamin D-deficient chick epiphyseal cartilage, the relationship of proteolipid to other tissue lipids, and its ability to supportin vitro apatite formation. Proteolipid was isolated from the upper growth centers (reserve cell zone, upper proliferative zone) and lower growth centers (lower proliferative, hypertrophic, and calcified cartilage zones) of long-bone epiphyses from 3-week-old normal and rachitic male white leghorn chicks by Sephadex LH-20 chromatography of the crude phospholipid component of the total lipid extract. In both normal and rachitic tissue the proteolipid/dry weight and proteolipid/total lipid ratios were greater in the lower growth center than in the upper zones. No statistically significant change in the proteolipid/total lipid ratio in rachitic tissues relative to comparable cell zones in normal cartilages was observed. However, there was an increase in the nonproteolipid phospholipid content of rachitic tissues, altering the relative proteolipid/phospholipid composition. Whereas proteolipids from normal tissue supportedin vitro calcification, proteolipids from rachitic tissues did not, indicating a direct effect of vitamin D on proteolipid structure. These data support the hypothesis that failure of rachitic cartilage to calcifyin vivo may be due in part to alterations in phospholipid and proteolipid metabolism.
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