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  • 1
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Une nouvelle méthode d'insertion de tube oesophagien est proposée. Chez les malades qui présentent des tumeurs oesophagiennes sténosantes inopérables, l'introduction du tube au travers du cancer a pour but de supprimer la dysphagie et la salivation. La technique consiste d'abord à dilater le défilé tumoral par l'appareil de Eder-Puestow puis à introduire correctement le tube sous contrôle endoscopique. 28 malades ont bénéficié de l'introduction d'un tube dit de Célestin. La méthode n'est grevée que de rares complications. Elle représente une alternative aux méthodes chirurgicales d'introduction d'un tube endo-oesophagien.
    Notes: Abstract A new method for inserting endoesophageal tubes is described. In patients with stenosing, inoperable esophageal malignancies, a passage through the neoplastic masses must be secured to avoid dysphagia and salivation. By first dilating the tumor lumen with the Eder-Puestow apparatus and then inserting the correctly cut tube using endoscopic equipment, an operation can be avoided. In 28 patients, a Celestin tube was thus inserted. The method involved only a few complications. It can be recommended as an alternative to existing operative methods for endoesophageal intubation.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs font état du traitement de 364 malades atteints de cancer de la partie distale de l'oesophage et de la jonction oesophagogastrique. Quatre-vingt deux pour cent (82%) des malades ont été opérés, le taux de résection ne dépassant pas 52%. Lors de l'intervention 230 de ces sujets présentaient des métastases lymphatiques et 115 présentaient des métastases à distance au niveau des organes abdominaux. Le taux de résection fut plus élevé chez les sujets qui présentaient un cancer squameux par rapport à ceux qui présentaient un adénocarcinome. Environ 2/3 des résections furent considérés comme “curatives”. La mortalité opératoire au total s'est élevée à 24% mais son taux a sensiblement décru au cours des 10 dernières années. Le taux de survie à 5 ans est le même que celui publié dans d'autres séries. Il est à noter que le taux de survie chez les patients atteints de cancer squameux fut nettement plus élevé que celui des sujets porteurs d'un adénocarcinome. Si la résection chirurgicale est impossible il est indiqué d'établir un court-circuit digestif au-dessus de la lésion ou d'intuber celle-ci. Ces méthodes donnent une rémission satisfaisante dans la majorité des cas.
    Abstract: Resumen Este informe se refiere al tratamiento de 364 pacientes con carcinoma de la porción distal del esófago y de la unión cardioesofágica. El 82% de los pacientes fué sometido a operación y la tasa de resección fué de 52%. En la operación se encontró que 230 pacientes tenían metástasis a ganglios linfáticos y que 115 tenían metástasis a órganos abdominales. La tasa de resección fué significativamente mayor en pacientes con carcinoma escamocelular que en los pacientes con adenocarcinoma, y alrededor de 2/3 de las resecciones fueron consideradas como tratamiento “curativo”. La mortalidad operatoria para la totalidad del período fué alta (24%), pero disminuyó en los últimos 10 anos. La tasa de supervivencia a cinco años después de la resección fué del mismo nivel que en otras series; la supervivencia fué considerablemente mayor en pacientes con carcinoma escamocelular que en los pacientes con adenocarcinoma. Cuando la resección quirúrgica no es practicable, está indicada una esofagogastrostomía de tipo “bypass” o la intubación. Estos procedimientos proveen una paliación satisfactoria en la mayoría de los pacientes al mejorar la calidad de la vida, la cual es bastante superior cuando el paciente puede corner y beber.
    Notes: Abstract The treatment of 364 patients with carcinoma of the distal part of the esophagus and the esophagogastric junction is reported. Eighty-two percent of the patients were subjected to operation and the resect ability rate was 52%. At operation 230 patients had lymph node metastases and 115 patients had distant metastases to abdominal organs. The resection rate was significantly higher in patients with squamous cell carcinoma than in patients with adenocarcinoma, and about two-thirds of the resections were considered as “curative” treatment. The operative mortality rate for the entire period was high (24%), but the mortality decreased in the last 10-year period. The 5-year survival rate after resection was in the same level as in other series; the survival rate for patients with squamous cell carcinoma was considerably higher than for patients with adenocarcinoma. If surgical resection is not feasible, surgical bypass of the obstructing lesion is indicated. This alternative procedure gives satisfactory palliation in the majority of patients.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: A fish respirometer-metabolism chamber was used to obtain in vivo respiratory-cardiovascular and chloroethane gill flux data on transected channel catfish (Ictalurus punctatus). Methods used for spinal transection, attachment of an oral membrane (respiratory mast), placement and attachment of blood cannulas and urine catheters are described. Respiratory physiology, cardiac output and chemical extraction efficiencies for 1,1,2,2-tetrachloroethane (TCE), pentachloroethane (PCE), and hexachloroethane (HCE) were determined on 419–990 g catfish. The overall mean values (± s.d.) for ventilation volume (Qv), effective respiratory volume (Qw), oxygen consumption (Vo2 and percentage utilization of oxygen (U) were 17-3 ±4–71 h−1 kg−1, 9·8±l·71 h−1 kg−1, 71·6±12·5mg h−1 kg−1, and 49± 10%, respectively, while cardiac output calculated via the Fick Method was 2·4±0·61 h−1 kg−1. Additional measurements were made on ventilation rate (Vr), total plasma protein, haematocrit (Hct), and urine volume; while both arterial and venous blood were analysed for pH, oxygen partial pressure (P02), carbon dioxide partial pressure (Pco2), total oxygen (To2), total carbon dioxide (Tco2) and total ammonia (TAMM). Physiological measurements taken at 24 h were not significantly different from those taken at 48 h and indicated no deterioration of the in vivo preparation. All of these values agreed well with literature values on UTitransected channel catfish, except for Hct which was lower for cannulated animals used in this study. Overall, these data provide strong support for the use of transected channel catfish for in vivo collection of physiological and chemical gill flux data.The mean initial chemical extraction efficiencies for TCE, PCE and HCE were 41, 61 and 73%, respectively. Chemical clearances (ClX) for these same three chemicals were 5·9, 9·3 and 10·8 1 h−1 kg−1, respectively. The approximate 1: 1 relationship between effective respiratory volume (Qw) and chemical clearance (Clx) indicated that branchial uptake of PCE and HCE was water flow-limited. Chemical gill flux observed for channel catfish and chloroethanes was similar to that observed for rainbow trout in previous studies and provided further support for the flow-limited model of chemical flux across fish gills.
    Type of Medium: Electronic Resource
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