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  • 1
    ISSN: 1432-1076
    Keywords: Key words Cardiac myxoma ; Childhood
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 10-year-old boy presented with unspecific symptoms and laboratory abnormalities simulating a chronic recurrent inflammatory disorder. Cardiovascular symptoms were absent. After 2 years of intermittent symptoms and persisting laboratory signs of an inflammatory disorder, echocardiographic evaluation revealed a large left atrial tumour. Immediate surgical excision confirmed the diagnosis of a cardiac myxoma and resulted in freedom from symptoms and normalization of laboratory parameters. Conclusion A cardiac myxoma can present with unspecific and extracardiac symptoms. It should be considered in the differential diagnosis of unclear chronic inflammatory or chronically recurrent febrile illness suggesting an auto-immune vasculitis or collagen disorder.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1076
    Keywords: Cardiac myxoma ; Childhood
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 10-year-old boy presented with unspecific symptoms and laboratory abnormalities simulating a chronic recurrent inflammatory disorder. Cardiovascular symptoms were absent. After 2 years of intermittent symptoms and persisting laboratory signs of an inflammatory disorder, echocardiographic evaluation revealed a large left atrial tumour. Immediate surgical excision confirmed the diagnosis of a cardiac myxoma and resulted in freedom from symptoms and normalization of laboratory parameters.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study details the structural and ultrastructural features of the interfaces between titanium implants and their surrounding tissues. The material stemmed from an experiment in dogs in which guided tissue regeneration with Gore-Text membranes was used to treat peri-implant, ligature-induced tissue breakdown around submerged and nonsubmerged com-mercially pure titanium implants. Specimens from the nonsubmerged group were evaluated under light microscopy and scanning and transmission electron microscopy. A healthy gingiva and a gingival sulcus were formed around the implant necks. A regenerated junctional epithelium provided the epithelial union between implant and gingiva. The supracrestal connective tissue was characterized by a 3-dimensional network of collagen fibers, fibroblasts and blood vessels. Near the implant surface the collagen fibers ran parallel to the titanium surface or were orientated perpendicular to the implant. The connective tissue-implant interface was characterized by a fine fibrillar material interposed between the implant surface and the connective tissue. An unidentified material was also observed between the endings of functionally orientated collagen fibrils and the metallic surface. The apical portions of the implants were anchored in compact bone. At the bone-implant interface, either mineralized bone matrix was intimately adapted to the titanium surface without any intervening space or a 0.5 μm wide unmineralized layer was interposed. These findings indicate that a perimucosal seal was formed around the implants consisting of a junctional epithelium-implant union coronally and supported by the connective tissue-implant junction apically. The implants were integrated in connective tissue, but only tightly adapted to bone.
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The histopathology of human root caries was examined in extracted teeth by different optical methods. The present part of the study details the sequential stages of initial caries in both cementum and peripheral dentin. Significant differences are shown between the mechanisms operating on the various dental hard tissues during development of caries. Histologically distinguishable reaction patterns depended on both the degree of the cariogenic challenge and the respective structural features of cementum and peripheral dentin. Earliest lesions, histologically visible as small clefts traversing cementum and extending into peripheral dentin, were clinically not detectable. Cementum was stepwise destroyed until peripheral dentin became exposed. The exposed peripheral dentin was sclerosed and tubule-free. Demineralization of dentin preceded the degradation of the organic matrix. Frequently, a hypermineralized layer occurred in both cementum and exposed dentin. Its localization was not identical with the anatomical surface. Initial penetration of bacteria into peripheral dentin occurred along small clefts. Breakdown of the organic matrix was the final step in the destructive phase of the carious process.
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  • 5
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The present study details the structural and ultrastructural features of healing events between the regenerated periodontal ligament and the root surface after experimental periodontal disease. Experiments were performed on dogs, and the concept of guided tissue regeneration was tested using resorbable polyurethane membranes. Light microscopy, scanning- and transmission electron microscopy were employed to determine if healing events involve regeneration (ie, process by which the architecture and the function are completely renewed) or periodontal repair (ie, healing of a wound by tissue that does not fully restore the architecture of a part). Regeneration occurred in parts of the roots only if some original cementum remained on the root surface after root planing. Repair was observed if peripheral dentin was removed by root planing as this layer was not reestablished. In areas remote from the base of the defect, new collagen fibrils, synthesized by fibroblasts and oriented perpendicular to the root surface, were spliced with severed ends of Sharpey's fiber bundles of original cementum. If circumpulpal dentin was exposed, intermingling between new fibrils with dentinal matrix fibrils occurred. In areas near the base of the defect, the first event was the formation of a cementoid by a cementoblast monolayer and subsequent formation of intrinsic fibrils oriented parallel to the root surface. Afterwards, the cementoblast monolayer disintegrated and extrinsic fiber bundles became anchored in the new cellular mixed fiber cementum. In these areas, linkage between new cementum and pre-existing tissues always occurred by interfacial intermingling of the fibrils, regardless of whether new attachment occurred at circumpulpal dentin or original cementum.
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  • 6
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The purpose of this study was to compare clinical, radiographic and histological differences around titanium oral implants loaded with either acrylic-veneered metal or ceramo-metal fixed prostheses. Five beagle dogs were used in this investigation. At the beginning of the study, all mandibular premolars and first molars were extracted. After 3 months of healing, 2 Brånemark implants were installed on each side of the mandibles. Three months later, abutments were inserted on each implant and a daily oral hygiene regime was initiated. One month after abutment connection, the implants on one side of the mandible were restored with an acrylic-veneered metal fixed prosthesis, whereas, on the other side a ceramo-metal fixed prosthesis was inserted. The prostheses were constructed in occlusion with the maxillary first molars. The following clinical parameters were measured around each implant at this time (i.e., baseline), and thereafter, at monthly intervals up to 5 months: Plaque Index; Gingival Index; implant mobility (using the Periotest®); probing depth and clinical attachment level (using the Florida Probe®). In addition, standardized radiographs were taken at baseline and 5 months after insertion of the prostheses and evaluated by subtraction radiography. Another Brånemark fixture was installed on each side of the mandibles 3 months before the end of the study. These implants remained unloaded and submerged for the entire study period. Five months after prosthesis insertion, the animals were killed, and implants with their supporting peri-implant tissues were processed for histological evaluation. Analyses of the clinical, radiographic and histometric parameters revealed no significant differences between the acrylic-veneered and ceramometal loaded implants. All clinical and radiographic parameters remained stable over time. Histological comparison of the alveolar bone height levels around both loaded groups with those from the unloaded, submerged implants revealed that a similar and slight loss of bone height (approximately 0.6 mm) occurred on the loaded groups following abutment connection. It was concluded that both acrylic-veneered metal and ceramo-metal suprastructures appear to be suitable for the restoration of endosseous oral implants. Additional long-term studies in humans, however, are needed evaluating both types of implant-supported prostheses, in a variety of clinical conditions. before final restorative recommendations are made.
    Type of Medium: Electronic Resource
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