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  • 1
    Unknown
    Stuttgart : Schattauer
    Call number: S020:11
    Keywords: Nuclear Medicine
    Pages: 351 p. : ill.
    Edition: 5., überarb. u. aktualisierte Aufl.
    ISBN: 3-7945-2237-0
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    S020:11 departmental collection or stack – please contact the library
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  • 2
    Call number: WN440:29(8)
    Keywords: Nuclear Medicine
    Pages: xv, 464 p. : ill.
    Edition: 8., vollständig überarb. Aufl.
    ISBN: 9783794531097
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    WN440:29(8) on loan
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  • 3
    Call number: E010:19
    Keywords: Nuclear Medicine
    Pages: xv, 441 p. : ill.
    Edition: 7., überarb. u. aktualisierte Aufl.
    ISBN: 978-3-7945-2889-9
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    E010:19 departmental collection or stack – please contact the library
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  • 4
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    Stuttgart : Schattauer
    Call number: 08-Nukl
    Keywords: Nuclear Medicine
    Pages: xv, 380 p. : ill.
    Edition: 3., überarb. und erweiterte Aufl.
    ISBN: 3794518128
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    08-Nukl departmental collection or stack – please contact the library
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  • 5
    Unknown
    Stuttgart : Schattauer
    Call number: E020:29
    Keywords: Nuclear Medicine
    Pages: xiv, 384 p. : ill.
    Edition: 6., überarb. u. aktualisierte Aufl.
    ISBN: 978-3-7945-2438-9
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  • 6
    ISSN: 1619-7089
    Keywords: Rhinorrhea ; Cerebrospinal-fluid scintigraphy ; 111In-DTPA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In an attempt to detect occult or intermittent rhinorrhea, 10 patients without and 9 cases with rhinorrhea were investigated after a lumbal injection of 1.3 mCi 111In-DTPA. Significant count rates were detectable in the nasal pledgets of all individuals, so that it was not possible to distinguish those with and those without rhinorrhea. Therefore, the ratio of activity in nasal pledgets and blood normalized for weight recommended by McKusick et al. was used. In the patients without evidence of rhinorrhea, the ratio did not exceed 2.0, whereas in 8 of the 9 cases with rhinorrhea, it was considerably increased. The detectability of rhinorrhea was increased by using more than one measurement and by provocation manoeuvres.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1619-7089
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1619-7089
    Keywords: Key words: Technetium-99m methoxyisobutylisonitrile – Iterative reconstruction – Parathyroid adenoma – Primary hyperparathyroidism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The purpose of this study was to assess the value of technetium-99m methoxyisobutylisonitrile (MIBI) single-photon emission tomography (SPET) and an iterative reconstruction algorithm for the preoperative localisation of parathyroid adenomas (PTAs). Seventy-two patients (26 male, 46 female, mean age 58±16 years) with known primary hyperparathyroidism were examined preoperatively. First, a thyroid examination was performed to detect possible MIBI-accumulating thyroid lesions. Planar scans were then acquired 15 and 120 min and tomographic images 120 min after intravenous injection of 740 MBq 99mTc-MIBI, using a triple-head gamma camera (Picker Prism 3000). Additionally, 99mTc-MIBI/ 99mTc-pertechnetate subtraction scintigraphy of the early planar images was performed. The SPET data were evaluated using an iterative reconstruction (multiplicative iterative SPET reconstruction: MISR) as well as a standard algorithm (FBP: filtered back-projection with application of a 3-D low-pass postfilter). The weight of the resected PTAs ranged from 110 mg to 5 g. Using planar MIBI scans, correct localisation of the side of the PTA was possible in 81% of cases (58% for PTAs weighing less than 500 mg). Sensitivity increased to 94% using SPET and FBP, while with MISR it rose further, to 97%. Patients with PTAs weighing less than 500 mg showed a sensitivity of 88% with MISR and 81% with FBP. Furthermore, there was a clear improvement in image quality using MISR. None of the normal parathyroid glands were visualised. This study indicates that, in comparison with planar scintigraphy, 99mTc-MIBI SPET is a more sensitive and specific tool for topographical localisation of PTAs, especially those that are small. There is a further improvement in sensitivity and image quality when iterative reconstruction is used instead of FBP.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-0743
    Keywords: magnetic resonance imaging ; valvular heart disease ; valvular stenosis ; Doppler echocardiography ; left ventricular function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Magnetic resonance techniques can be employed to depict valvular abnormalities but are especially helpful in quantifying regurgitant or stenotic lesions which cannot be quantitatively assessed by other noninvasive techniques. Gradient echo techniques and phase velocity mapping are the most important magnetic resonance pulse sequences employed for these purposes. Valvular regurgitation can be quantitated by measuring the area of signal void on conventional gradient-echo images, by calculating stroke volume differences from k-space segmented gradient echo images, by measuring the proximal convergence zone from velocity encoded images or by comparing stroke volumes of the ventricles from velocity measurements. In contrast to this variety of possibilities in regurgitant lesions, stenotic lesions can only be quantitated by using velocity mapping techniques. Magnetic resonance spectroscopy can be used to assess myocardial metabolism in chronic valvular lesions. However, this tool needs further development and more clinical data before its use can be recommended to assess the necessity and optimal timing of surgical intervention.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-0743
    Keywords: coronary artery disease ; dipyridamole ; gradient-echo magnetic resonance imaging ; 99mTc-methoxyisobutyl-isonitrile-SPECT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Magnetic resonance imaging (MRI) has been used in conjunction with dipyridamole induced wall motion abnormalities for the noninvasive detection of coronary artery disease (CAD). To assess the clinical usefulness of dipyridamole-MRI for the localization of CAD and to evaluate the relation between dipyridamole induced wall motion abnormalities and myocardial perfusion 33 patients with severe CAD (〉70% diameter reduction) underwent MRI at rest and after dipyridamole infusion (0.75 mg dipyridamole/kg over a period of 10 minutes). All patients performed exercise stress testing and 20 patients of the study group additionally had rest and exercise stress99mTc-methoxyisobutyl-isonitrile-SPECT (MIBI-SPECT). Two patients (6%) could not be evaluated due to severe motion artifacts during dipyridamole MRI. Segmental wall motion and perfusion of corresponding short axis planes were related to the major coronary arteries using a standardized segmental coronary artery perfusion pattern. Detection of wall motion abnormalities or perfusion defects by 2 blinded observers in consensus was the criterion for grading a segment normal or pathologic. For localization of CAD, segmental gradings were related to the presumed coronary artery territories. Stress-ECG was pathologic in 19/31 patients yielding a sensitivity of 61% and dipyridamole induced angina was present in 68% (21/31) of patients. Dipyridamole-MRI detected coronary artery disease with a sensitivity of 84% (26/31 patients) and all patients with new wall motion abnormalities also had dipyridamole induced angina. For the subgroup of 20 patients with MIBI-SPECT images, CAD was detected by both MIBI-SPECT and Dipyridamole-MRI in 90% (18/20) of patients. Dipyridamole-MRI and MIBI-SPECT gradings agreed in 55/60 (92%) coronary artery perfusion territories. There were no significant differences with respect to the sensitivities of Dipyridamole-MRI/MIBI-SPECT for the localization of individual coronary artery stenoses yielding 81%/78% for left anterior descending, 80%/80% for left circumflex and 92%/89% for right coronary artery stenoses. However, specificity of Dipyridamole-MRI (89%) for the detection of RCA stenoses was slightly better than for MIBI-SPECT (80%). Dipyridamole-MRI induced regional wall motion abnormalities proved to be a highly sensitive parameter for the non-invasive localization of CAD. The similarity of dipyridamole-MRI and MIBI-SPECT results suggests a close agreement between functional and perfusion parameters in the assessment of hemodynamically significant coronary artery stenoses. The clinical utility of this MRI stress test is still limited by high cost and long imaging times which may, however, be overcome by the development of new shorter imaging sequences.
    Type of Medium: Electronic Resource
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