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  • 1
    ISSN: 0584-8539
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2242
    Keywords: Tertiary trisomic ; Pentavalents ; Pearl millet ; Transmission of trisomics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Nineteen tertiary trisomics were isolated from some translocation heterozygotes and interchange trisomics of pearl millet. Cytological analysis of these trisomics indicates that chromosome association of trivalents, univalents and pentavalents were frequent in all the trisomics. But their ratio varied from one trisomic to the next. Other associations were relatively infrequent. The relative frequencies of 6 pentavalent configurations observed in different trisomics were studied and their probable association with mode of fertility and transmission rates have been discussed.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2242
    Keywords: Chromosome transmission ; Pearl millet ; Trisomic series ; Trivalent frequency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Transmission rates of extra chromosomes found in the full set of trisomics of pearl millet (Pennisetum americanum) (2n = 14) were estimated by examining the progeny of selfed trisomics and the progeny of trisomics crossed to disomics. When the trisomics were selfed, ‘dark green’ and ‘tiny’ had the highest transmission rate (23.8% and 23.3%, respectively) and ‘pseudonormal’ the lowest (13.8%). Other trisomics had an intermediate rate of transmission. When the trisomics were used as females in crosses with disomics, both ‘dark green’ and ‘tiny’ again had the highest transmission rate and ‘pseudonormal’ the lowest. When the trisomics were used as males in crosses to disomics, no trisomic was transmitted to the progeny except for ‘spindle’, and this occurred with a very low frequency (2.0%). A variation in transmission rate was observed from plant to plant and season to season for the same trisomic type. A study of the transmission rate of the extra chromosomes indicated that the following factors were probably contributing to the lower rate of transmission: small- or light-weight seeds tended to have a higher proportion of trisomics than heavier seeds; lighter seeds had a lower percentage germination; a positive and significant correlation was noticed between trivalent frequency and transmission rate. Plants with reduced vigour produced a higher frequency of trisomics. Though trisomics involving longer extra chromosomes showed a high degree of pollen and ovule sterility, they were highly transmissible. This has resulted in a close relationship between gametic sterility and transmission rate of extra chromosome.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-072X
    Keywords: Rhizobium ; Virus ; Morphology ; One step growth ; General characterization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A virus (RL 1) that infects Rhizobium leguminosarum was isolated and studied. The virus has phagelike morphology; it has a hexagonal head and a long, flexible, noncontractile tail with a baseplate. The edgeto-edge diameter of head is 760 Å. The tail is 1515 Å long and 115 Å wide. RL 1 is stable at 4° C in distilled water, with only 20% loss in the titer after one month storage. It does not require any ion for stability, and is stable between pH 6.0 and 8.0. The virus is composed of two components; one is thermal sensitive and the other is relatively thermal resistant. Adsorption and ‘one step growth’ experiments under normal growth conditions showed a slow adsorption rate (0.82×10-9 cm3 min-1) followed by a 90 min latent period. The burst size was approximately 100 virus particles per cell.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 30 (1974), S. 1405-1406 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Der Effekt von Nickel (Ni) auf die Vermehrung des Kartoffelvirus in der Tomatenpflanze (Lycopersicum esculentum Mill cv. Marglobe) wurde untersucht. In Abhängigkeit vom Nickel-Spiegel nahm sowohl das vegetative Wachstum der Pflanze, der Virus, wie auch der Gesamtgehalt an Stickstoff und freien Aminosäuren zu.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 266 (1977), S. 40-41 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It is well known that the global thunderstrom activity is at a maximum at the temperate latitude and decreases with increasing latitudes7. The parameters or mechanisms controlling the guidance of thunderstorm-generated low-frequency waves are less effective at low latitude, however, which seems to ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 225 (1970), S. 49-50 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] VLF observations at high latitudes are correlated with the influx of electrons1,2. VLF outbursts are also observed at low latitude stations3, and in trying to explain the origin of these VLF waves, Gurnett3 discarded the Čerenkov process because he was not able to find any correlation with ...
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Earth, moon and planets 65 (1994), S. 89-94 
    ISSN: 1573-0794
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Cosmic ray particles passing through dense lower atmosphere of Venus decay giving rise to various charged and neutral particles. The flux and degradation of dominant cascade particles namely neutrinos and pions are computed and ionization contributions at lower altitudes are estimated. Using the height profile of pion flux, the muon flux is computed and used to estimate ionization at lower altitudes. It is shown that cosmic ray produced ionization descends to much lower altitudes intercepting the thickness of Venus cloud deck. The dynamical features of Venus cloud deck are used to allow the likely charging and charge separation processes resulting into cloud-to-cloud lightning discharges.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: High throughput, low-temperature deposition, sharp interfaces, and selective deposition with direct ion-, electron-, and photon-beam-controlled techniques are some of the key driving forces for the development of superconducting thin films by metalorganic chemical vapor deposition (MOCVD) technique. In this paper we report on the electrical and structural properties of Y-Ba-Cu-O (YBCO) films deposited by MOCVD on yttrium-stabilized zirconia (YSZ) and BaF2/YSZ substrates using a single-step in situ processing method which requires no further annealing. YBCO films deposited on BaF2/YSZ substrates have zero resistance at 80 K. The films were characterized by energy dispersive x-ray analysis, x-ray diffraction, scanning electron microscopy, and transmission electron microscopy. The films on BaF2/YSZ substrates exhibited textured growth having both the c and a axis perpendicular to the substrate. The use of BaF2 as a buffer layer suggests three-dimensional integration of high-temperature superconducting thin film for hybrid superconductor/semiconductor devices as well as superconductor switches and other related devices.
    Type of Medium: Electronic Resource
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  • 10
    Keywords: IN-VITRO ; BLOOD ; IN-VIVO ; MODEL ; VITRO ; SYSTEM ; SYSTEMS ; liver ; ENZYMES ; GENE-EXPRESSION ; METABOLISM ; TISSUE ; MICE ; ACTIVATION ; DNA ; CARCINOGENESIS ; DNA ADDUCT FORMATION ; ENVIRONMENTAL CONTAMINANT 3-NITROBENZANTHRONE ; TISSUES ; MOUSE ; NO ; DIFFERENCE ; mass spectrometry ; METABOLIC-ACTIVATION ; POLLUTANT 3-NITROBENZANTHRONE ; POLYCYCLIC AROMATIC-HYDROCARBONS ; MASS-SPECTROMETRY ; CHROMATOGRAPHY ; LIQUID-CHROMATOGRAPHY ; CLEARANCE ; MOUSE MODEL ; PHARMACOKINETICS ; cytochrome P450 ; ORDER ; BODIES ; ONCOLOGY ; RE ; KNOCKOUT MICE ; LEVEL ; analysis ; MASS ; LOSSES ; PROSTAGLANDIN-H SYNTHASE ; ENGLAND ; ANTICANCER DRUG ELLIPTICINE ; CONDITIONAL DELETION ; DETERMINES SUSCEPTIBILITY
    Abstract: Many studies using mammalian cellular and subcellular systems have demonstrated that polycyclic aromatic hydrocarbons, including benzo[a]pyrene (BaP), are metabolically activated by cytochrome P450s (CYPs). In order to evaluate the role of hepatic versus extra-hepatic metabolism of BaP and its pharmacokinetics, we used the hepatic cytochrome P450 reductase null (HRN) mouse model, in which cytochrome P450 oxidoreductase, the unique electron donor to CYPs, is deleted specifically in hepatocytes, resulting in the loss of essentially all hepatic CYP function. HRN and wild-type (WT) mice were treated intraperitoneally (i.p.) with 125 mg/kg body wt BaP daily for up to 5 days. Clearance of BaP from blood was analysed by high-performance liquid chromatography with fluorescence detection. DNA adduct levels were measured by P-32-post-labelling analysis with structural confirmation of the formation of 10-(deoxyguanosin-N-2-yl)-7,8,9-trihydroxy-7,8,9,10-tetrahydrobenzo[a]py rene by liquid chromatography-tandem mass spectrometry analysis. Hepatic microsomes isolated from BaP-treated and untreated mice were also incubated with BaP and DNA in vitro. BaP-DNA adduct formation was up to 7-fold lower with the microsomes from HRN mice than with that from WT mice. Most of the hepatic microsomal activation of BaP in vitro was attributable to CYP1A. Pharmacokinetic analysis of BaP in blood revealed no significant differences between HRN and WT mice. BaP-DNA adduct levels were higher in the livers (up to 13-fold) and elevated in several extra-hepatic tissues of HRN mice (by 1.7- to 2.6-fold) relative to WT mice. These data reveal an apparent paradox, whereby hepatic CYP enzymes appear to be more important for detoxification of BaP in vivo, despite being involved in its metabolic activation in vitro
    Type of Publication: Journal article published
    PubMed ID: 18204078
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