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  • 1
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  35. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2017); 20170111-20170114; Chur, Schweiz; DOC17dav10.7 /20170118/
    Publication Date: 2017-01-18
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 2
    facet.materialart.
    facet.materialart.
    German Medical Science GMS Publishing House; Düsseldorf
    In:  35. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2017); 20170111-20170114; Chur, Schweiz; DOC17dav7.6 /20170118/
    Publication Date: 2017-01-18
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 3
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  34. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2016); 20160113-20160116; Berchtesgaden, Deutschland; DOC16dav64 /20160112/
    Publication Date: 2016-01-13
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 4
    ISSN: 1433-2965
    Keywords: Key words:Morphometric radiography – Morphometric X-ray absorptiometry – Osteoporosis – Precision – Vertebral deformities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: Morphometric techniques, which use conventional lateral spine radiographs to quantify vertebral body shape (morphometric radiography, MRX), have proved a useful tool in the identification and evaluation of osteoporotic vertebral deformities. Recently a new method of acquiring the images required for vertebral morphometry using dual-energy X-ray absorptiometry scanners (morphometric X-ray absorptiometry, MXA) has been developed. In this study we compare repeat analysis precision of vertebral height measurement using MXA and MRX. Twenty-four postmenopausal women were recruited (mean age 67 + 5.8 years): 12 normal subjects and 12 with osteoporosis and vertebral deformities. Each subject had a MXA scan and lateral thoracic and lumbar radiographs at a single appointment, which were each analyzed quantitatively in a masked fashion, using a standard 6-point method, twice by one observer and once by a second observer. Anterior (Ha), mid (Hm) and posterior (Hp) vertebral heights were measured and wedge (Ha/Hp) and mid-wedge (Hm/Hp) ratios calculated for each vertebral body. Intra- and interobserver precision were consistently poorer in MXA compared with MRX in both normal subjects and those with vertebral deformities, with MXA CV% generally at least 50% higher than corresponding values for MRX. For both MXA and MRX interobserver precision was clearly poorer than intraobserver precision, a problem associated with any morphometric technique. MXA intra- and interobserver precision were significantly poorer for subjects with vertebral deformities compared with those without, with a CV% for deformity subjects up to twice that of normal subjects. Conversely, MRX showed little or no obvious worsening of intra- or interobserver precision for deformity subjects. Comparison of MXA precision in the normal and deformed vertebrae of the deformity subjects demonstrated that the poorer precision in these subjects compared with normal subjects was the result of increased variability in point placement on the deformed vertebrae themselves. However, the precision for normal vertebrae in these subjects was also somewhat poorer than the precision in normal subjects. We conclude that MXA precision is generally poorer than that of MRX and that the presence of vertebral deformities has a more pronounced effect on MXA precision than on MRX precision.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1433-2965
    Keywords: Key words: Dual X-ray absorptiometry – Morphometric X-ray absorptiometry – Osteoporosis – Vertebral fractures – X-ray absorptiometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The accurate identification of prevalent vertebral fractures is important in both the clinical and research setting as they are associated with increased risk of further fracture and irreversible clinical consequences. This study reports a direct comparison of prevalent vertebral deformity identification using X-ray absorptiometry (XA) scans, acquired on a dual-energy X-ray absorptiometry (DXA) machine, and conventional radiographs in a diverse group of 161 postmenopausal women, ranging from healthy subjects with normal bone mineral density (BMD) to osteoporotic subjects with multiple vertebral deformities. Deformities were identified by a trained operator by visual assessment of the XA scans (VXA) and semiquantitatively by an experienced radiologist on the conventional radiographs (XSQ). Subjects were recruited prospectively and were triaged according to their VXA results into normal, equivocal and definite deformity groups. VXA and XSQ demonstrated good agreement (96.3%, κ= 0.79) in classifying vertebrae as normal or deformed in the 1978 of 2093 vertebrae deemed analyzable on both the XA scans and conventional radiographs. VXA showed good sensitivity (91.9%) in the identification of moderate/severe XSQ deformities and an excellent negative predictive value (98.0%) was produced when VXA was used to distinguish subjects without vertebral deformities from those with possible or definite deformities on a per subject basis. The majority of disagreement between the two methods resulted from different classification of mild wedge and endplate deformities and the poor visualization of upper thoracic vertebrae on the XA scans. Agreement improved, particularly on a per subject basis, when analysis was restricted to the vertebral levels from L4 to T7. Visual triage of XA scans by a trained operator would seem to be swift, convenient and cost-effective method, with excellent negative predictive value, to distinguish subjects with very low risk of vertebral deformities from those with possible deformities. These ‘normal’ subjects can then be excluded prior to performing conventional radiographs and further time-consuming and costly methods of vertebral deformity assessment such as XSQ by an experienced radiologist and/or quantitative morphometry. VXA may prove useful in the clinical evaluation of patients at risk of osteoporosis as an adjunct to BMD scans or in the selection of subjects for osteoporosis-related clinical trials.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1433-2965
    Keywords: Absorptiometry (X-ray) ; Bone density ; Morphometry ; Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The diagnosis of vertebral fractures has been based on lateral thoracic and lumbar spine films and entails the determination of crush, endplate and wedge deformities of the vertebral bodies, generally between T4 and L4. Accuracy and precision of X-ray based morphometry are limited by geometric distortion and other technique-related factors. This paper proposes the use of morphometric X-ray absorptiometry (MXA) as a method which overcomes many of the limitations of morphometric radiography. MXA generates paired anteroposterior and lateral images of the spine using a scanning fan beam geometry that significantly reduces distortions inherent in the cone beam geometry used in conventional X-rays. Intra-observer precision of MXA on 41 subjects aged 65 years and older was 1 mm for vertebral height assessments and 4.7% for vertebral wedge parameters. Linear correlation with vertebral heights and wedge parameters on 32 subjects evaluated by both MXA and morphometric radiography demonstrated a root of the mean squared error of 2.1–2.4 mm and 7.0%, respectively. Vertebral deformities could be identified by MXA. The study documents the feasibility of MXA for the assessment of vertebral deformities. However, further investigation is needed to document the ability of MXA to diagnose prevalent and incident fractures.
    Type of Medium: Electronic Resource
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  • 7
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019); 20190109-20190112; Schladming, Österreich; DOC14 /20190108/
    Publication Date: 2019-01-09
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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