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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The ACI or BDIV rats responded with decreased or increased neutrophil levels in blood after the N-methyl-N-nitrosourea (MNU) administration. The F1 hybrids had decreased neutrophil counts, and the BDIV × (BDIV × AC1)Fl backcross offspring showed two phenotypes. The sex of the rats and the neutrophil response to MNU assorted independently. The results indicated that the neutrophil response to MNU was regulated by autosomal gene Nrm-1 with two alleles. The Nrm-Id regulates the decrease and the Nrm-1i regulates the increase of neutrophils in blood after the MNU administration. The results were confirmed by the SKUMIX computer program.We found that the Nrm-1 gene was linked to the agouti locus (chi-square = 10–3, P 〈 0.001). The map distance between two genes was 33 ± 5 cM. The Nrm-1 gene thus resides on the linkage group IV of the rat.
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 182 (1958), S. 52-52 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] By means of a minor modification of the procedure of Bowden et al. we have succeeded in detecting thyroxine in 1.0 ml. of serum. The chromatogram was sprayed with a solution (1:1) of ceric ammonium sulphate (0.2 N) - sodium arsenite (1-0N) and left approximately 15 min. to dry at room temperature ...
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Biochemical genetics 22 (1984), S. 893-899 
    ISSN: 1573-4927
    Keywords: diabetes insipidus ; agouti ; hooded
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Linkage of the hooded (h), agouti (A), and diabetes insipidus (di) genes was found in (ACI×DI)F1×DI backcross rats. The genetic map distance A-di for females and for males was 19±5 and 28±5 cM, respectively. However, this difference was not significant. The combined data showed the map distance to be 25±4 cM. The three-point cross showed the following corrected distances and order of genes: h-42±4-A-25±4-di. However, the linkage of h and A, although significant (x2=9.03, P〈0.001), is only tentative and must be confirmed by additional studies.
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  • 4
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Es werden die Störungen bei der katalytischen Beschleunigungswirkung von Jodid auf die Reaktion zwischen Cer(IV) und Arsen(III) (nach Sandell u. Kolthoff) untersucht. Als störend wird jede Veränderung der Geschwindigkeitskonstanten um ±5% (entsprechend ±0,001 μg I−) betrachtet. Mehr als 0,3 mg KBr, 1,0 mg CuSO4, 4,0 mg MgSO4 oder 40,0 mg NaCl verursachen eine Änderung um +5%, während mehr als 0,04 mg NaF, 1,0 mg KH2PO4, 5 mg Na+, 40,0 mg KCl oder 65,0 mg ZnSO4 eine solche von — 5% verursachen.
    Notes: Summary On the basis of changes in the rate constant values in the Sandell-Kolthoff reaction, amounting to ±5 percent, the concentrations of agents, responsible for these changes and equivalent to ±0.001 μg of I−, were determined. It was found that these substances, in the amounts given, stimulate the reaction, viz.: KBr 0.3 mg; CuSO4 1.0 mg; MgSO4 4.0 mg; NaCl 40.0 mg, while the following cause a lowering of the iodine value by 0.001 μg: NaF 0.04 mg; KH2PO4 1.0 mg; Na+ 5mg; KCl 40.0 mg and ZnSO4 65.0 mg.
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  • 5
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Die optimalen Bedingungen für die Bestimmung von Ultramikromengen Jod mit Hilfe der Sandell-Kolthoff-Reaktion wurden ausgearbeitet. 1-m Natriumchloridlösung sowie 0,1-n arsenige Säure und 0,005-n Cer-Ammonium-sulfatlösung werden im Verhältnis As3+: Ce4+=20 verwendet. Das Reaktionsgemisch soll an Schwefelsäure am besten 2,5-n sein. Die Verwendung eines Eisbades (+ 4° C) und von Brucin zur Erzielung einer konstanten Farbe wird begründet. Die Möglichkeit der Ermittlung einer Eichkurve durch Auftragung des Logarithmus der Extinktion gegen die Jodkonzentration wird gezeigt.
    Abstract: Résumé On a mis au point les conditions optimales du dosage de quantités d'iode à l'échelle ultramicro par la réaction deSandell etKolthoff. On a utilisé des solutions de chlorure de sodium 1,0 M, d'anhydride arsénieux 0,1N et de sulfate de cérium et d'ammonium 0,005N dans le rapport As3+/Ce4+=20. On a trouvé que la concentration optimale en acide sulfurique dans le milieu réagissant était de 2,5N. On a justifié l'emploi d'un bain de glace (+ 4° C) et de la brucine pour l'obtention de la stabilité de la couleur. On a montré la possibilité de construire la courbe d'étalonnage à partir de la densité optique au lieu de la concentration en iodure.
    Notes: Summary Optimal condition were determined for the determination of ultramicroquantities of iodine by the Sandell-Kolthoff reaction. Solutions of 1.0M sodium chloride, 0.1N arsenic trioxide and 0.005N cericammonium sulphate in the ratio of As3+/Ce4+=20 were used. The optimum concentration of sulphuric acid in the reacting medium was found to be 2.5N. Justification was given for the use of an ice bath (+ 4° C) and of brucine to obtain a stable colour. Evidence is provided for the possibility of plotting the calibration curve from log extinction against iodine concentration.
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  • 6
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Eine universelle Methode zur Bestimmung von Nanogramm-Mengen Jod in verschiedenen biologischen Materialien wird beschrieben. Zugesetzte Jodmengen wurden durchschnittlich zu 95% wiedergefunden. Die Standard-abweichung der Methode beträgt ±5%.
    Abstract: Résumé On décrit une méthode universelle pour le dosage de quantités de l'ordre du nanogramme (1 ng=10−9 g) d'iode dans les différents types de substance biologique. La concordance avec l'iode étalon ajouté atteint en moyenne 95% environ. La déviation standard de la méthode est de ±5%.
    Notes: Summary A universal method for the determination of nano-amounts (ng= =10−9 g) of iodine in various types of biological material is described. The recovery of added iodine standard averaged around 95%. The standard deviation for the method is ± 5%.
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  • 7
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Geeignete Arbeitsvorschriften für die Zerstörung biologischen Materials für die Bestimmung von Nanogramm-Mengen Jod werden angegeben. Das jodhältige Material wird in einer Sauerstoffatmosphäre in einer Platindrahtspule verbrannt, die Verbrennungsprodukte werden innerhalb 30 Minuten in 0,66-n Sodalösung absorbiert. Die Standardabweichung der Methode beträgt 4,9%.
    Abstract: Résumé On décrit les conditions optimales pour la destruction de la substance biologique dans le dosage de l'iode en quantités de l'ordre du nanogramme (1 ng = 10−9g). On brûle la substance contenant de l'iode dans l'oxygène et sur un rouleau de platine et on l'absorbe pendant 30 minutes dans Na2CO3 0,66 N. La déviation standard de cette méthode est de 4,9 %.
    Notes: Summary Optimal conditions for the destruction of biological material in the determination of nano-amounts (ng = 10−9g) of iodine are described. The iodine-containing material is burned in oxygen on a platinum coil, and is absorbed over a period of 30 minutes in 0.66N Na2CO3. The standard deviation of this method is 4.9%.
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  • 8
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Sequencing and computational annotation revealed several features, including high gene numbers, unusual composition of the predicted genes and a large number of genes lacking homology to known genes, that distinguish the rice (Oryza sativa) genome from that of other fully sequenced model species. ...
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