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  • 1
    ISSN: 1432-1106
    Keywords: Cochlea ; Perfusion ; Elevated potassium ; Electrical potentials ; Recovery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Scala tympani (ST) in guinea pig was perfused with modified Ringer's solutions containing 5–50 mM potassium; tone-induced cochlear responses from the basal turn of ST were compared before, during and after perfusions. The compound nerve action potential (N1) and afterpotential (a/p) amplitudes were reduced, especially above 20 mM; the summating potential (SP) was variable, but its onset shape changed consistently with 13–20 mM levels. However, the cochlear microphonic amplitude (CM) remained substantially unchanged even at the 35 mM level. K+ concentration was monitored in ST with ion-sensitive pipettes. Stable levels were reached within 2 min, but N1 responses continued to fall beyond this time. Recovery to normal K+ levels took place spontaneously and the concentration curve which resulted showed a 2-slope characteristic. These experiments question whether elevated potassium concentration in scala tympani depolarizes the hair cells, and if it does, whether the hair cell resting potential is involved in the generation of the CM.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 40 (1980), S. 113-113 
    ISSN: 1432-1106
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1434-4726
    Keywords: Olivocochlear bundle ; Guinea pig ; Efferent neurones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have tried to quantify the number of efferent neurones comprising the olivocochlear bundle in the guinea pig by using the retrogradely transported fluorescent dye, true blue. The dye was injected into numerous regions of the cochlea for various distances. The data from 14 complete experiments have been evaluated. The majority of the labelled cells were found ipsilaterally, with the lateral superior olive containing 59.2% and showing cochleotopicity. Of the 28.9% found contralaterally, the nucleus of the ventral lateral lemniscus had 16.9%, and the trapezoid body nucleus 8.0%, differing significantly from the other nuclei of the superior olivary complex. Although the distribution of the labelling was consistent, there was great variability in actual numbers. Calculations based on cell density showed no differences along the length of the basilar membrane, and resulted in a total of around 2500 efferent neurones. This figure agrees closely with the maximum counts found by other workers. However, the cause of the individual variability remains unanswered.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé Une nouvelle méthode d'examen visuel facile du fundus des oiseaux est décrite ici. Elle utilise la transillumination de la tête. Cette méthode rend possible la photographie avec des appareils conventionnels. Elle n'exige pas une dextérité speciale, et grâce à elle, certaines caractéristiques peuvent être mises en evidence d'une facon plus nette qu'avec d'autres techniques.
    Type of Medium: Electronic Resource
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