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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physics Letters A 162 (1992), S. 41-44 
    ISSN: 0375-9601
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract To determine whether a chromosomal band is a fragile site rather than a spontaneous breakpoint, an essential step is to test the nonrandomness of breakage at the region. In this paper, the nonapplicability of the testing procedure introduced by Bohm et al. is discussed, and a new detection procedure is proposed. This new procedure considers the relations of one site with the others, and can be applied to tests of the nonrandomness of breakpoints under either the proportional probability model, or the equiprobability model. A data set for Chinese patients with colorectal carcinoma is analyzed as an illustration of the proposed method.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2234
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Mögliche Geometrien und die zugehörigen Spektren von Cyclobutadien wurden nach Pariser-Parr unter Einschlu\ der einfach und zweifach angeregten Konfigurationen berechnet. Die BindungslÄngen der stabilsten Form stimmen gut mit früheren Rechnungen mit anderen gewÄhlten Parametern überein, bei denen nur die einfach angeregten Konfigurationen berücksichtigt worden waren. Und zwar ergibt sich, da\ eine rechteckige Form (Singulett) stabiler als die quadratische (Triplett) ist. Allerdings hÄngt diese Geometrie von den gewÄhlten Parametern ab.
    Abstract: Résumé Les geometries possibles du butadiéne et les spectres électroniques correspondants ont été calculés par une méthode de Pariser-Parr motifiée avec interaction de configurations avec les états mono et diexcités des électrons π. Les longueurs de liaison des formes les plus stables sont en accord avec celles obtenues précédemment avec des paramètres empiriques différents dans un calcul ne tenant compte que des configurations monoexcitées. Dans notre calcul amélioré le singulet rectangulaire est plus stable que le triplet carré. La géométrie la plus stable dépend de l'approximation utilisée.
    Notes: Abstract The possible geometries for cyclobutadiene and the electronic spectra corresponding to those geometries were calculated by a modified Pariser-Parr method with inclusion of doubly-excited as well as singly-excited configurations in calculating the π-energy. The bond lengths of the most stable forms agreed well with previous calculations where the empirical parameters used in the π-energy calculation were different from those used here, and where only singly-excited configurations were included. With these additional refinements, the rectangular singlet is calculated to be more stable than the square triplet. It is noted that the geometry predicted to have the lowest energy is a function of the approximations employed.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary.  The 4.6-kb double-stranded (ds) RNA of Trichomonas vaginalis virus (TVV)-T1 has been shown to encode two overlapping genes, cap and pol. In this study, a serum for specifically detecting viral cap gene product was raised against a recombinant protein, and sera for specifically detecting pol gene product were raised against synthetic oligopeptides. A 75-kDa major protein and a 160-kDa minor protein were detected by anti-CAP serum in a TVV-T1 sample, indicating that the 75-kDa protein is the viral capsid protein. The 160-kDa protein alone was also detected by two distinct anti-POL sera, indicating that the pol gene is expressed as a CAP-POL fusion protein. These results suggest that the TVV-T1 genome is arranged into a cap-pol organization in a manner similar to that of viruses in family Totiviridae.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-2234
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Die Methode der teilweisen Vernachlässigung der differentiellen Überlappung (PNDO) wurde auf die im Titel genannten Heterozyklen angewandt, um totale Ladungsverteilungen zu erhalten. Diese wurden benutzt, um (halb-empirisch) molekulare Kerne zu konstruieren, die bei der VESCF Behandlung von π-Systemen benötigt wurden. CI-Verfahren wurden dann durchgeführt unter Verwendung der Grundkonfiguration und aller einfach und doppelt angeregten Konfigurationen. Da das Verfahren semiempirisch ist, muß man darauf achten, keine Parameter einzuführen, die inkonsistent sind mit unseren früheren Behandlungen von Kohlenwasserstoffen und Carbonylverbindungen mittels derselben Methoden. Die Resultate zeigen an, daß bei Verfolgung dieser Art von Schema, es wahrscheinlich endgültig möglich sein wird, auf einem allgemeinen a priori Weg die Elektronenspektren von π-Systemen bei Heterozyklen ebenso wie bei Kohlenwasserstoffen und Carbonylverbindungen mit einer dem Experiment vergleichbaren Genauigkeit auszurechnen.
    Abstract: Résumé La méthode du recouvrement différentiel partiellement nul (PNDO) a été appliquée aux hétérocycles afin d'obtenir des distributions de charge totale. Celles ci on été ensuite utilisées pour construire des squelettes moléculaires (semi-empiriques), employés dans la traitement VESCF des systèmes d'électrons π. L'interaction de configurations a été réalisée en utilisant toutes les configurations mono et di-excitées. Malgré le caractère semi-empirique de ce traitement, on a pris la précaution de ne pas introduire de paramètres qui présenteraient une incohérence avec notre traitement analogue des hydrocarbures et des composés carbonyles. Les résultats obtenus montrent qu'en suivant un tel schéma de calcul il serait probablement possible de calculer d'une manière générale à priori les spectres électroniques des systèmes π des hétérocycles, des hydrocarbures et des composés carbonyles, à la précision expérimentale.
    Notes: Abstract The partial neglect of differential overlap (PNDO) method has been applied to the heterocycles in the title to obtain total charge distributions. These have then been used to construct (semi-empirical) molecular cores, which have been used in the VESCF treatment of the π-systems. Configuration interaction treatments have then been carried out using the ground configuration, and all singly- and doubly-excited configurations. While the treatment is a semiempirical one, care has been taken to introduce no parameters which would be inconsistent with our earlier treatments of hydrocarbons and carbonyl compounds by the same methods. The results indicate that following this kind of scheme, it will probably be finally possible to calculate in a general a priori way the electronic spectra of π-systems of heterocycles, as well as hydrocarbons and carbonyl compounds, with an accuracy comparable with that of experiment.
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  • 6
    ISSN: 1432-0428
    Keywords: Islet cell transplantation ; streptozotocin-diabetic rats ; basement membrane ; retina
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Progressive basement membrane thickening is a characteristic structural abnormality in diabetic tissues in cluding the retina. We examined the effect of pancreatic islet allotransplantation on basement membrane thickening and irregularities in retinal capillaries of the streptozotocin-diabetic rat. Diabetic animals received intraportal or intracerebral pancreatic islet allografts. Animals with functioning allografts demonstrated euglycaemia and a normal body weight gain during the 400-day post-transplantation period. The characteristic thickening of capillary basement membranes was completely prevented in animals with successful transplantation. The present findings suggest that islet allotransplantation may be a rational therapeutic approach in the treatment of diabetes mellitus and the prevention of ensuing secondary complications.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0428
    Keywords: Artificial endocrine pancreas ; capillaryunit ; xenogeneic ; pancreatic islets ; transplantation ; diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An implantable artificial endocrine pancreas consisting of a coiled single acrylic copolymer capillary surrounded by rat islets (1000/kg body weight) was implanted in 10 streptozotocin-alloxan diabetic dogs. About 5 h following implantation plasma glucose decreased from an initial mean value of 350 mg/dl to 150 mg/dl, and then to 100 mg/dl at 12 h. Plasma insulin increased to a mean of 39 mU/l (range 23–83 mU/l) at 5 h in the recipient animals. In addition a much improved plasma glucose disappearance rate (K = 1.9 ±0.3) with slightly delayed insulin responses was seen after intravenous glucose tolerance tests performed in 4 dogs at 7, 8, 10 and 18 h following implantation. These findings suggest that xenogeneic rat islets implanted as an artificial endocrine pancreas can improve glucose metabolism in the diabetic dog.
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  • 8
    ISSN: 0020-708X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-7640
    Keywords: Binary tree ; context-free programmed grammar ; context-sensitive languages ; control diagram ; grammatical inference ; semantics ; semantic rule ; stochastic grammar ; syntactic pattern recognition ; tree grammar
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract An important property of Context-Free Programmed Grammars (CFPG) is that some context-sensitive Languages can be generated by CFPG. To infer a special class of CFPG for syntactic pattern recognition is the motivation of this paper. First an one-dimensional string is transformed into a corresponding binary tree. Then in terms of the structure of subtrees, and the semantic rules corresponding to the context-free productions, a method for the inference of Context-free Programmed Grammar is presented. Inference of Stochastic Context-Free Programmed Grammar (STCFPG) by the maximum-likelihood estimate approach is also discussed.
    Type of Medium: Electronic Resource
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