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  • 1
    ISSN: 1434-9949
    Keywords: Reiter's syndrome ; Sexual couples ; Chlamydia Trachomatis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary With sexually transmitted rheumatic diseases in mind we investigated 37 male sexual partners of females with Reiter's syndrome (RS) or suspicion of RS (SRS). Controls were 219 randomly selected interviewed males. A history of urogenital involvements was found in 19/37 (51,4%) as compared to 65/219 (29,7%). Anamnestic nonspecific urethritis, dysuria, gonorrhoea, condylomata acuminata and prostatitis occurred more frequently in the 37 males than in the controls (p〈0.05-p〈0.025). Six out of 37 as compared to 5 of 219 had a history of balanitis (p〈0.0025). Anamnestic synovitis was found in 8/37 (21,6%) and in 9/219 (4,1%) (p〈0.001) RS or SRS was diagnosed in 6/37 (16,2%). Taking into consideration the consecutive females with RS or SRS, whose sexual partners were not investigated, the theoretical counting still shows clear differences in the anamnestic occurrence of synovitis and balanitis between the 37 males and the controls (p〈0.0125 - p〈0.05). The results emphasize the important role of sexually acquired and maintained RS in rheumatology.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Infection 10 (1982), S. S5 
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die durchChlamydia trachomatis (Immuntyp D bis K) verursachten Genital-Infektionen werden in einer kurzen Übersicht dargestellt. Die Urethritis ist die wichtigste Chlamydien-Infektion beim Mann und zugleich die häufigste sexuell übertragene Erkrankung. Die Komplikationen dieser nicht durch Gonokokken verursachten oder postgonorrhoisch auftretenden Urethritis umfassen Prostatitis, Epididymitis und Arthritis. Bei Frauen treten Urethritis und Zervizitis als Primärinfektionen auf, die zu Salpingitis, Peritonitis und Perihepatitis führen können. Die Übertragung der Chlamydien-Infektion auf das Neugeborene erfolgt unter der Geburt. Daraus kann sich eine Konjunktivitis oder Pneumonie entwickeln. Neben einer kurzen Übersicht über die Diagnose und Behandlung der genitalen Chlamydien-Infektionen werden allgemeine Empfehlungen gegeben.
    Notes: Summary Genital infections caused byChlamydia trachomatis (immunotypes D to K) are briefly reviewed. Urethritis is not only the most important chlamydial infection in men, but is also the most common sexually transmitted disease. The complications of this form of nongonococcal or postgonococcal urethritis include prostatitis, epididymitis and arthritis. Urethritis and cervicitis are the primary infections in women, and may lead to salpingitis, peritonitis or perihepatitis. Chlamydial infection is transmitted to the infant at birth, causing conjunctivitis or pneumonia. The diagnosis and treatment of genital chlamydial infections are briefly reviewed. Finally, some general recommendations on genital chlamydial infections are presented.
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  • 3
    ISSN: 1432-1335
    Keywords: Transitional cell ; Bladder tumour ; Nuclear image analysis ; Mitotic index ; WHO grade ; Papillary status ; Clinical stage ; Progression ; Survival
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A retrospective histological analysis has been carried out on 537 cases of transitional-cell bladder carcinoma, followed-up over a period of 9 years. In the first part of the study WHO grade 2 tumours were analysed and a number of independent factors predictive for survival identified. In a multivariate analysis the T category and M/V index (number of mitotic figures/mm2 neoplastic epithelium) were the most important prognostic factors. In a subsequent analysis of the whole series of 537 cases, overall the M/V index was not as important in predicting survival as the stage of the tumour. However, in superficial tumours (Ta−T1) subsequent analysis showed that the M/V index alone could be used to predict survival.
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  • 4
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A solid-phase radioimmunoassay (RIA) using egg-grown purifiedChlamydia trachomatis lymphogranuloma venereum (LGV) serotypes L1, L2, and L3 as antigen was used to measure type-specific IgG and IgA antibodies in sera of 36 patients who had contracted LGV infection about 40 years ago. The RIA test gave compatible results with the standard microimmunofluorescence test, and by RIA it was possible to identify the infecting serotype in 30 out of 36 patients studied. In 28 cases this was L2 and in two cases L1. Each patient had IgG antibodies and most of them (80%) IgA antibodies to at least one of the LGV serotypes. The antibody titers were still high 40 years after the acute infection, being higher than in male patients with a recent chlamydial urethritis. Highest antibody titers were detected in LGV patients who had a severe disease with intestinal involvement.
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  • 5
    ISSN: 1434-9949
    Keywords: Reiter ; Sexual Couples ; Chlamydia Trachomatis ; Yersinia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To examine the occurrence of signs and symptoms of Reiter's syndrome (RS) in female sexual partners of males with RS we have investigated 43 female consorts of 42 males, originating from 72 consecutive patients suffering from RS or suspicion of RS (SRS). Anamnestic mono-, oligo- or polyarthritis occurred in 14 of the 43 females (32,6%) as compared to 28 out of 311 randomly selected interviewed controls (9,0%). Five of the 43 females had RS and 7 had SRS, (27,9%). However, the diagnosis could have been possible with only anamnestic information in 6 (14%) as compared to 7 out of 311 controls (2,3%). Taking into consideration the 30 males whose sexual partners were not investigated, the theoretically counted values still differ significantly from those of the controls (p〈0.01). A history of urogenital and, on the other hand, nasopharyngeal or pulmonary infectiouns involvements preceded equally frequently the first or further joint attacks. Evidence of chlamydial infection was found in 53,5 % (32/43) of the partners while Yersinia antibodies measured by ELISA occurred with the same frequency as among healthy blood donors. We would like to stress the importance of various infectious involvements, especially sexually transmitted diseases, as etiological agents in joint attacks in females who are sexual partners of males with RS.
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  • 6
    ISSN: 1434-9949
    Keywords: Reiter's Syndrome ; Chlamydia Trachomatis ; Sexual Couples
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The occurrence of urogenital involvements in female sexual partners of males with Reiter's syndrome (RS) or suspicion of RS (SRS) was studied. The possible etiological role of Chlamydia trachomatis (Ct) was demonstrated by isolation and by immunofluorescence (IF) serology. Evidence of chlamydial infection (positive isolation and/or IF titre≥64) was found in 35 out of 56 (62,5%) males with RS and in 9 out of 16 (56,3%) males with SRS. 43 female sexual partners of these men were studied. Evidence of present or past chlamydial infection was demonstrated in 23 of these 43 females (53,5%). This was a significantly higher frequency than that evidenced among controls studied, 14/77 verified serologically and 3/81 by isolation, p〈0.0025 and p〈0.005, respectively. A history of dysuria occurred in 10 out of 43 female sexual partners and in only 20 out of 364 interviewed randomly selected controls (p〈0.00025). Abnormal urinary findings were also more frequent among the sexual partners than among the controls (p〈0.025). The results emphasize the role of Ct as a triggering factor in RS and stress the importance of urogenital investigations among couples with RS.
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  • 7
    ISSN: 1434-9949
    Keywords: Female Reiter's ; Chlamydia Trachomatis ; Female Uro-Arthritis ; Pyuria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To study the nature of urogenital involvements in female uro-arthritis 73 consecutive patients with arthritis concomitant with any type of urogenital involvement were examined. The controls were 281 females interviewed only and an additional 83 also gynaecologically examined. A history of cervicitis, salpingitis, dysuria and pyelocystitis/-nephritis occurred significantly more often in patients than in controls. Clinical gynaecological examination revealed cervicitis in 26,8 % (19/71) of the patients and 15.7 % (13/83) of the controls (p〈0.05). Aseptic pyuria was definitely more frequent in patients (19/73) than in controls (0/63). The isolation of Chlamydia trachomatis was positive in 14.7 % (10/68) of the patients and 3.7 % (3/81) of the controls (p〈0.025). Serological evidence (titre ≧ 64) for chlamydial infection was obtained in 53.4 % (39/73) of the patients and 18.2 % (14/77) of the controls (p〈 0.00025). The results indicate the importance of urogenital history and findings in females with rheumatic attacks. The most prominent and persistent urogenital involvements were cervicitis, salpingitis, pyuria and dysuria. Chlamydial infection appears in any case to be responsible for part of these involvements (42/73).
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  • 8
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. The aetiological role of Chlamydia trachomatis (CT) and herpes simplex virus (HSV) was investigated in 189 patients with threatened abortion. Assessment of infection was based on isolation, and on determination of serum immunoglobulin (Ig)G and IgA antibodies as well as cervical IgA antibody levels with new sensitive radioimmunoassay (RIA) techniques. One third of the women were delivered of a healthy infant and two thirds aborted, but the two groups were otherwise clinically similar. By isolation, only 2.7% of the patients were CT-positive, but increased cervical IgA antibody level to CT was detected in 41.3%. The mean level of these local antibodies was similar in both study groups, but the mean levels of serum IgA and IgG antibodies were somewhat higher in the patients who aborted although the difference was not significant. None of the cervical specimens was positive for HSV by isolation but the cervical IgA antibody level to HSV was raised in 47.1% of the patients. Both cervical and serum IgA antibody levels to HSV were significantly raised among the patients who aborted, but there were no differences between the patients with spontaneous abortion and those with a blighted ovum. There was no clear association between CT and abortion, but an association between HSV and abortion is possible. The incidence of raised levels of both CT and HSV IgA antibodies in the cervix was surprisingly high in both groups and the significance of this finding remains to be investigated.
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  • 9
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The association of Chlamydia trachomatis (CT) and herpes simplex virus (HSV) with malignant or premalignant changes in the cervix uteri was studied by determining immunoglobulin A (IgA) antibodies in the cervical secretions of 28 women with inflammatory, 28 with dysplastic, 7 with malignant changes of the uterine cervix, and 26 healthy controls. In cervical secretions IgA antibodies to CT were found in 24 of 35 (69%) patients with malignant or premalignant changes, in 11 of 28 (39%) with cervicitis and in 3 of 26 (12%) controls. IgA antibodies to HSV were found in 10 of 35 (28%) patients with malignant atypia or dysplasia but in none of the women with cervicitis or the controls. The highest frequency of antibodies was found in the patients with cervical carcinoma. Serum IgA antibodies to CT and HSV were found equally in the patients and the controls. Our results suggest that in patients with cervical atypia, local IgA CT antibody production occurs. Whether this association is aetiological or coincidental can not be concluded from this study.
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 47 (1992), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A study of the prevalence atopic disorders among 15–16-year-old teenagers was carried out in a coastal urban town in south-western Finland. Altogether, 1712 children were found in that age group, all previously examined by a pediatrician. Each child who had present or previous allergic diseases was invited for a detailed study, a total of 434 (25%) pupils. Of these patients 416 (95.8%) participated in clinical examination and skin testing. The prevalence of atopic diseases was 21% in the studied group; atopic eczema was found in 9.7%, allergic rhinitis in 14%, and asthma in 2.5%. Of subjects who had rhinitis, 38% also had atopic eczema, while rhinitis - as the only symptom -was found in 8.8%. Figures obtained from this survey suggest that the prevalence rates of atopic diseases are about the same as found 10 years age in Finland and they correspond also with other recent reports.
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