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  • 1
    ISSN: 1432-1084
    Keywords: Diffuse liver disease ; MRI ; CT ; Ultrasound
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Twenty-nine patients with diffuse liver disease were examined by ultrasound, CT and MRI. MRI was performed using T1- and T2-weighted spin-echo sequences as well as fast gradient-echo-sequences. The paramagnetic contrast agent Gd-DTPA was applied intravenously (0.1 mmol/kg). in patients with hepatitis, MRI could be used in guiding liver biopsies as inflammatory changes were clearly delineated. CT and ultrasound were superior to MRI in the detection of focal or diffuse fatty degeneration. On the other hand MRI was more helpful in differentiating fatty changes and neoplasm. In liver cirrhosis, fibrotic changes were most clearly demonstrated by MRI. In patients suffering from hemochromatosis MRI offers advantages over CT and ultrasound in the diagnosis and follow up due to the paramagnetic properties of iron, resulting in a reduction in signal intensity. In patients with Wilson's disease a characteristic pattern of parenchymal changes was seen. Administration of Gd- DTPA contributes additional information about perfusion conditions in the liver parenchyma, however this information was not of diagnostic relevance in the cases we studied.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: MR ; Perfusion study ; Brain ; Necrosis ; Edema ; Neoplasms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to characterize intracranial tumors based on MR measurements of regional cerebral blood volume. In 8 patients without intracranial pathology and 42 patients with intracranial tumors a T2*-weighted image series was acquired during bolus injection of gadolinium-DTPA, and regional cerebral blood volume maps were calculated. The regional cerebral blood volume index (rCBVi) of vital tumor was expressed in percent of the value measured in contralateral gray matter. In extra-axial tumors (meningiomas) rCBVi was higher (124 ± 110%), and in low-grade intra axial tumors rCBVi was lower (79 ± 65%), than in contralateral cortex. In malignant intra-axial tumors the distribution of rCBV was heterogenous: high in vital tumor (glioblastomas: rCBVi = 165 ± 85%; metastases: rCBVi = 106 ± 79%), but low in necrosis (rCBVi = 33% of contralateral white matter) and edema (rCBVi = 53% of contralateral white matter). rCBVi was highest in arteriovenous malformations (1053 ± 584% of contralateral gray matter). We conclude that the regional cerebral blood volume distribution is useful to characterize intracranial tumors, although the large biological variability of individual tumor entities indicates limitations.
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  • 3
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To date, myoepithelial sialoadenitis (Sjoegren's syndrome) has been diagnosed with sialography and other techniques. First results of MR imaging offer new possibilities in the diagnostic imaging of this Thirty-six pat nts with immunohistologically and serologically confirmed Sjoegren s syndrome and 25 patients suffering from other diseases, included as a control group, were examined by MR in transverse and coronal orientation T-2 weighted sequneces (TR/TE- 1600/25/90) and T- weighted sequences (TR/TE 500/25 msplainand after (Gd-DTPA administration were obtained. In all patients the parotid gland showed characteristics internal paterns and abnormalities in gland size. There was a 21 nonhomogeneous internal pattern wit a characteristicsc speckled, honeycomb-like appearance visible especially on T2-weighted sequences. Enhancement with Gd-DTPA yielded no additional information. A staging system with four stages of Sjoegren's syndrome (no characteristics changes to a nodular and swollen gland) was developed. Magnetic resonance has become an important new tool in assessing parotid gland changes in patients suffering from Sjoegren's syndrome, and could well replace the more invasive and unpleasant diagnostic methods in the near future.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 6 (1996), S. 75-75 
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 6 (1996), S. 78-78 
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 6 (1996), S. 311-311 
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1084
    Keywords: Key words: Interventional MRI ; Interstitial therapy ; MR-guided laser-induced interstitial thermotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The rationale and results for interstitial therapies via interventional MRI in the treatment of tumors in various regions are presented. Different interstitial treatment techniques are presented based on varying technologies both for tumor ablation and treatment monitoring. Data are presented based on 335 patients, 29–84 years of age (mean age 59 years, 196 men and 139 women) with a total of 932 liver tumors, 16 head and neck tumors and 14 abdominal recurrent pelvic and lymphatic tumors. All lesions had been treated with MR-guided laser-induced interstitial thermotherapy (LITT) via 2516 laser applications and 1856 cannulations. Data in the literature are extremely varying depending on author experience, treatment technique, and the included patient material. In our patient material we were able to achieve a local tumor control of 96.7 % depending on the size of the tumorous lesion, the topographical relationship, and the applied laser parameters. The overall cumulative survival rate of patients with liver metastases was 45.74 months (median 40.97 months, 95 % confidence interval 31.42–50.52). The cumulative survival rate of the patient group with hepatic metastases of colorectal carcinoma was 42.71 months (median 39.33 months, 95 % confidence interval 33.26–45.37). In patients with head and neck tumors a relevant reduction in clinically relevant symptoms such as pain, swallowing disorders, or nervous compression was achieved in 11 of 15 patients treated with LITT. In 14 soft tissue tumors, such as pelvic tumor recurrence and lymph node metastases, a local tumor control was obtained in 68 % of lesions. Interstitial therapies under interventional MRI guidance, such as LITT, results in a high local tumor control with an improved survival rate.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 9 (1999), S. 1247-1251 
    ISSN: 1432-1084
    Keywords: Key words: MRI ; Head and neck imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The purpose of this paper is to describe current imaging protocols for MR imaging of the head and neck region and to define results and clinical impact. Depending on the clinical question, different MRI protocols are presented for imaging of the head and neck. The appearance of different pathologic findings on imaging studies and how adapted imaging protocols help to improve differential diagnosis is discussed. In summary, MRI is the method of choice for imaging of the head and neck.
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  • 9
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 3 (1993), S. 196-196 
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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