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  • 1
    Keywords: Germany ; IMAGES ; ACCURACY ; INTEROBSERVER VARIABILITY ; RESOLUTION ; PATIENT ; MAGNETIC-RESONANCE ; ACQUISITION ; AGE ; WOMEN ; MEN ; arteries ; MAGNETIC-RESONANCE ANGIOGRAPHY ; HYPERTENSION ; STANDARD ; SUBSET ; METAANALYSIS ; STENOSIS ; HIGH-SPATIAL-RESOLUTION ; RENAL-ARTERIES ; BALLOON ANGIOPLASTY ; INTRAVASCULAR ULTRASOUND
    Abstract: PURPOSE: To retrospectively compare three-dimensional gadolinium-enhanced magnetic resonance (MR) angiography, performed with an integrated parallel acquisition technique for high isotropic spatial resolution, with selective digital subtraction angiography (DSA) and intravascular ultrasonography (US) for accuracy of diameter and area measurements in renal artery stenosis. MATERIALS AND METHODS: The study was approved by the institutional review, board, and consent was obtained from all patients. Forty-five patients (17 women, 28 men; mean age, 62.2 years) were evaluated for suspected renal artery stenosis. Three-dimensional gadolinium-enhanced MR angiograms were acquired with isotropic spatial resolution of 0.8 X 0.8 X 0.9 mm in 23-second breath-hold with an integrated parallel acquisition technique. In-plane diameter of stenosis was measured along vessel axis, and, perpendicular diameter and area of stenosis were assessed in cross sections orthogonal to vessel axis, on multiplanar reformations. Interobserver agreement between two radiologists in measurements of in-plane and perpendicular diameters of stenosis and perpendicular area of stenosis was assessed with mean percentage of difference. In a subset of patients, degree of stenosis at MR angiography was compared with that at DSA (n = 20) and intravascular US (n = 11) by using Bland-Altman plots land correlation analyses. RESULTS: Mean percentage of difference in stenosis measurement was reduced from 39.3% +/- 78.4 (standard deviation) with use of in-plane views to 12.6% +/- 9.5 with use of cross-sectional views (P 〈.05). Interobserver agreement for stenosis, grading based on perpendicular area of stenosis was significantly better than that for stenosis grading based on in-plane diameter of stenosis (mean percentage of difference, 15.2% +/- 24.2 vs 54.9% +/- 186.9; P 〈.001). Measurements of perpendicular area of stenosis on MR angiograms correlated well with those on intravascular US images (r(2) = 0.90). CONCLUSION: Evaluation of cross-sectional images reconstructed from high-spatial-resolution three-dimensional gadolinium-enhanced MR renal angiographic data increases the accuracy of the technique and decreases interobserver variability. (C) RSNA, 2005
    Type of Publication: Journal article published
    PubMed ID: 15770035
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  • 2
    ISSN: 0378-1119
    Keywords: B-lymphoblast ; HPRT ; PCR ; crystallization ; recombinant DNA ; x-ray diffraction analysis
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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