Springer Online Journal Archives 1860-2000
Summary Linkage data on human factor H (HF) and 22 other human genetic markers are presented. Close linkage at 0〈0.10 can be ruled out for a series of marker systems (Rh, PGM1, ACP1, Jk, Tf, Gc, MNSs, ME2, HLA, GLO1, ORM, Gt, PI, Hp, GPT). Strong evidence for linkage was obtained for peptidase A (PEPA) with lods 〉3.0 at Θ=0.10 in males and at Θ=0.20 for the sexes combined. From this result the HF locus can be provisionally assigned tochromosome 18.
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