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  • 1
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    German Medical Science; Düsseldorf, Köln
    In:  57. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20060511-20060514; Essen; DOCP 10.148 /20060508/
    Publication Date: 2006-07-31
    Keywords: Arterio-venous malformations ; VEGF ; Angiogenesis ; Arterio-venöse Malformation ; VEGF ; Angiogenese ; ddc: 610
    Language: English
    Type: conferenceObject
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  • 2
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    German Medical Science; Düsseldorf, Köln
    In:  57. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20060511-20060514; Essen; DOCP 02.12 /20060508/
    Publication Date: 2006-07-31
    Keywords: acute rhabdomyolysis ; anticonvulsive drugs ; phenytoin ; Akute Rhabdomyolyse ; Antikonvulsiva ; Phenytoin ; ddc: 610
    Language: English
    Type: conferenceObject
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  • 3
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    German Medical Science; Düsseldorf, Köln
    In:  57. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20060511-20060514; Essen; DOCFR.12.06 /20060508/
    Publication Date: 2006-07-31
    Keywords: neuroendoscopy ; complications ; third ventriculostomy ; Neuroendoskopie ; Komplikationen ; Ventrikulostomie ; ddc: 610
    Language: English
    Type: conferenceObject
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  • 4
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    German Medical Science; Düsseldorf, Köln
    In:  57. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20060511-20060514; Essen; DOCSA.09.04 /20060508/
    Publication Date: 2006-07-31
    Keywords: orbital meningeoma ; proptosis ; cranio-orbital approach ; Orbitameningeom ; Exophthalmus ; Kranioorbitotomie ; ddc: 610
    Language: English
    Type: conferenceObject
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  • 5
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    German Medical Science; Düsseldorf, Köln
    In:  55. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 1. Joint Meeting mit der Ungarischen Gesellschaft für Neurochirurgie; 20040425-20040428; Köln; DOCP 08.82 /20040423/
    Publication Date: 2004-04-22
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 6
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    German Medical Science; Düsseldorf, Köln
    In:  56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 3èmes journées françaises de Neurochirurgie (SFNC); 20050507-20050511; Strasbourg; DOCP200 /20050504/
    Publication Date: 2005-05-05
    Keywords: ddc: 610
    Language: English
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  • 7
    ISSN: 1434-3940
    Keywords: Schlüsselwörter Schädelbasistumor ; Kraniofazialer Zugang ; Frontobasis ; Key words Skull-base tumor ; Craniofacial approach ; Anterior cranial base
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Most tumors of the anterior cranial base invade both the intra- and extracranial regions at the borderline of the cranial and facial skeleton. In surgical treatment of these lesions, combined craniofacial approaches are applied in accordance with the anatomical conditions. Surgery is performed by an interdisciplinary team of neurosurgeons and maxillofacial surgeons. To evaluate the effectiveness and the complications of this surgical concept, the data of 58 patients treated over a 10-year period were collected. In these patients, 60 operations were performed, including two operations for tumor recurrence. In 38 cases, complete tumor removal was achieved. One patient died in the early postoperative period because of pulmonary embolism. Significant neurological deficits occurred in three patients. In most cases, postoperative complications and functional disability were both due to intradural invasion of the tumor. Nevertheless, in the majority of the cases radical tumor removal is achieved with acceptable morbidity when microsurgical techniques are applied for the resection of the intradural tumor. Both the meticulous repair of dural defects and the reconstruction of the anterior cranial base and orbit contribute distinctly to a reduction in the rate of postoperative complications and to acceptable cosmetic results.
    Notes: Zusammenfassung Tumoren der frontalen Schädelbasis entwickeln sich im Grenzgebiet von Hirn- und Gesichtsschädel häufig mit einer Ausbreitung nach intra- und extrakranial. Bei der operativen Behandlung wird diesen anatomischen Gegebenheiten durch kombinierte kraniofaziale Zugangswege Rechnung getragen, die von einem interdisziplinären Operationsteam durchgeführt werden. Um die Effektivität und Komplikationen dieses Behandlungskonzepts zu überprüfen, wurden die Daten von 58 Patienten aus den letzten 10 Jahren zusammengestellt. Bei diesen Patienten wurden mit 2 Rezidiveingriffen 60 Operationen durchgeführt. Bei 38 Eingriffen gelang eine vollständige Tumorexstirpation. Durch eine Lungenembolie ereignete sich ein postoperativer Todesfall. Funktionell relevante neurologische Defizite traten bei 3 Patienten auf. Postoperative Komplikationen und funktionelle Beeinträchtigungen wurden v. a. durch eine intradurale Tumorinvasion verursacht. Mit der Anwendung mikrochirurgischer Operationstechniken bei der Resektion der intraduralen Tumoranteile läßt sich meist eine radikale Tumorexstirpation bei akzeptabler Morbidität erreichen. Rekonstruktive Maßnahmen bei Defekten im Bereich der Dura und des Knochens tragen entscheidend dazu bei, postoperative Komplikationen zu vermeiden und ein zufriedenstellendes kosmetisches Behandlungsergebnis zu erzielen.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0942-0940
    Keywords: Cervical spine ; tumour ; trauma ; infection ; operative treatment ; spondylectomy ; microsurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 44 patients with complex degenerative, traumatic, neoplastic and infectious disorders of the cervical spine an aggressive surgical approach was used, consisting of Spondylectomy, radical microsurgical decompression and osteosynthesis. The patient group consisted of 23 patients with multisegmental cervical spondylosis, 9 patients with primary or metastatic malignant tumour disease spread along the cervical spine, 6 patients with complex cervical trauma and 6 patients with infection affecting one or more cervical segments. Considering the heterogenity of the group of patients treated, a multitude of neurological symptoms and signs were present. Excruciating pain was the predominant symptom in 84% of the patients, followed by sensory and motor signs of varying degrees in 77% and 65% respectively. Involvement of the long tracts was present in 51%, gait disturbance in 49% and bladder disfunction in 28%. Considering the nature of the underlying disease, in the group with multisegmental cervical spondylosis (MSCS), advanced cervical myelopathy was the predominant clinical symptom, whereas in those patients with trauma, tumour or infection, pain was the leading symptom, followed by disturbed motor and/or sensory function. Altogether 59 vertebrae have been removed in the 44 patients. In 28 patients spondylectomy was performed at one level, in 15 patients at two levels and in one female tumour patient at three levels. In 34 patients an iliac crest bone graft was used and in 10 patients bone cement. Within the observation period, solid fusion was achieved in all patients. In one tumour patient screw loosening was demonstrable at follow-up, but the fusion remained stable. 2 patients with infectious disease required re-operation due to significant loosening of screws and plates. However, after re-stabilization solid fusion was achieved. Considering amelioration of specific pre-operative symptoms and signs, excruciating pain responded best to the stabilizing procedure, with improvement in over 90% of the patients, followed by improvement of sensory and motor deficits in 85% and 82% respectively. Improvement in pre-operative gait disturbance could be achieved in 81% of the patients, while disturbance of bladder function is less likely to improve after surgery with a positive response in only 58%. None of the patients became neurologically worse after surgery. With regard to the underlying disease, patients with MSCS and tumour had the best results with overall improvement in 62% and 75% respectively. While in patients with infection improvement could be achieved in 58%, improvement in trauma patients was demonstrable in only 34% while in 66% the pre-operative clinical status remained unchanged. The surgical technique is described in detail, the results and four illustrative cases representing the therapeutic spectrum of this technique are presented. The necessity of strict adherence to microsurgical techniques for decompressive epidural surgery is especially stressed, as this is considered, apart from adequate osteosynthetic technique, to be the most important surgical factor determining the postoperative result in this challenging group of patients.
    Type of Medium: Electronic Resource
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