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  • 1
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    German Medical Science; Düsseldorf, Köln
    In:  Hypertonie 2005; 29. Wissenschaftlicher Kongress der Deutschen Hochdruckliga; 20051123-20051125; Berlin; DOC05hochP122 /20060808/
    Publication Date: 2006-08-09
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 2
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    German Medical Science; Düsseldorf, Köln
    In:  Hypertonie 2005; 29. Wissenschaftlicher Kongress der Deutschen Hochdruckliga; 20051123-20051125; Berlin; DOC05hochP117 /20060808/
    Publication Date: 2006-08-09
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 3
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    German Medical Science; Düsseldorf, Köln
    In:  Hypertonie 2005; 29. Wissenschaftlicher Kongress der Deutschen Hochdruckliga; 20051123-20051125; Berlin; DOC05hochP119 /20060808/
    Publication Date: 2006-08-09
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 4
    Keywords: IRRADIATION ; radiotherapy ; Germany ; FOLLOW-UP ; SUPPORT ; meningioma ; radiation ; PATIENT ; BASE ; MEMORY ; FORM ; DEFICITS ; stereotactic ; stereotactic radiotherapy ; CONFORMAL RADIOTHERAPY ; RADIATION-THERAPY ; LOCALIZATION ; CENTRAL-NERVOUS-SYSTEM ; DECLINE ; MEMORY IMPAIRMENT ; BENIGN MENINGIOMAS ; INTRACRANIAL MENINGIOMAS ; RESECTED MENINGIOMAS ; DENTATE GYRUS ; fractionated stereotactic radiotherapy,meningioma,neuropsychology,cognitive effects,base of skull
    Abstract: Purpose: The purpose of this study was to evaluate the cognitive outcome after fractionated stereotactic radiotherapy (FSRT) in patients with base of skull meningiomas.Methods and material: A total of 40 patients with base of skull meningiomas were neuropsychologically evaluated before, after the first fraction (1.8 Gy), at the end of FSRT (n = 37), 6 weeks (n = 24), 6 (n = 18) and 12 months (n = 14) after FSRT. A comprehensive test battery including assessment of general intelligence, attention and memory functions was used. Alternate forms were used and current mood state was controlled.Results: After the first fraction a transient decline in memory function and simultaneous improvements in attention functions were observed. No cognitive deteriorations were seen during further follow-up, but increases in attention and memory functions were observed. Mood state improved after the first fraction, at the end of radiotherapy and 6 weeks after radiotherapy.Conclusion: The present data support the conclusion that the probability for the development of permanent cognitive dysfunctions appears to be very low after FSRT. The transient memory impairments on day 1 are interpreted as most likely related to an increase of a preexisting peritumoral edema, whereas the significant acute improvements in attention functions are interpreted as practice effects. An analysis of localization specific effects of radiation failed to show clear hemisphere specific cognitive changes. (C) 2003 Elsevier Ireland Ltd. All rights reserved
    Type of Publication: Journal article published
    PubMed ID: 14643955
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  • 5
    ISSN: 0009-8981
    Keywords: Calcitriol ; Extrelut-1-minicolumns ; Scintillation proximity assay ; Sep-Pak silica cartridges ; Vitamin D metabolites
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Der Radiologe 38 (1998), S. 210-217 
    ISSN: 1432-2102
    Keywords: Key words MR-Angiography • Interventional MRI • Intravascular MRI ; Schlüsselwörter Magnetresonanz-Angiographie • Interventionelle MRT • Intravaskuläre MRT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Obgleich die klinische Umsetzung des Konzeptes der Interventionellen MR-Angiographie noch in weiter Zukunft liegt, sind in den letzten Jahren die technischen Voraussetzungen für die Evaluation eines solchen Konzeptes geschaffen worden. So ermöglichen offene Gerätekonfigurationen einen zunehmend freien Zugang des Untersuchers zum Patienten. Hochleistungsgradientensysteme erlauben die Akquisition von komplexen dreidimensionalen Datensätzen, mit deren Hilfe das arterielle wie auch das venöse Gefäßsystem umfassend dargestellt werden kann. Mit der Entwicklung der MR-Tracking- und MR-Profiling-Methoden stehen nunmehr auch Techniken zur Verfügung, mit deren Hilfe intravaskulär geführte Katheter und Führungsdrähte beinahe in Echtzeit sichtbar gemacht werden können. Diese Übersichtsarbeit beschreibt die technischen Voraussetzungen zur Sichtbarmachung von Kathetern und Führungsdrähten in der MRT-Umgebung und beschreibt die Durchführung erster MRT-gesteuerter Interventionen am Tier sowie am Menschen. Darüber hinaus wird das Potential der intravaskulären Bildgebung zur Charakterisierung arteriosklerotischer Plaquestrukturen beleuchtet.
    Notes: Summary The flow sensitivity inherent to the MR experiment allows for the non-invasive assessment of both the arterial and venous vasculature in any desired plane with good spatial resolution. Data can be acquired in a three-dimensional form, permitting reformating in any plane. In addition, MRI is capable of providing quantitative blood flow information with the use of phase-contrast flow-mapping techniques. Ultrafast gradient echo and echoplanar data acquisition strategies even permit imaging in near-real time. The availability of open MRI configurations now permits one to take advantage of the unique imaging features inherent to MR imaging for the purpose of guidance and control of various intravascular procedures. With the recent development of the MR tracking and MR profiling techniques, permitting visualization of guide-wires and catheters relative to their surroundings in the MR environment in real time, one of the last obstacles to 'Interventional MR angiography' has in effect been overcome. In addition, MR catheters can be modified to acquire high-resolution MR images of the vascular wall, thereby opening vast possibilities regarding characterization of atherosclerotic plaques. This review introduces the underlying techniques for catheter and guide-wire visualization in the MR environment, describes preliminary interventions in animals and humans and discusses the potential of intravascular MRI.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-2102
    Keywords: Schlüsselwörter ; Herz ; Koronargefäße ; Koronarer Bypass ; Bypassverschluss ; EKG-getriggertes CT ; Key words ; Heart ; Coronary vessels ; Coronary artery bypass graft ; CABG patency ; ECG-triggered CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose: Assessment of coronary artery bypass graft (CABG) patency with computed tomography methods has been demonstrated as an alternative to coronary angiography. The evaluation of the bypass anastomoses is still of limited success. Prospective ECG triggering of conventional CT scanners al- lows heart phase-triggered single-slice acquisition in the sub-second range. The goal of this study was to evaluate whether the use of ECG triggering can optimize the evaluation of proximal CABG anastomoses. Materials and methods: In ten patients after CABG surgery, ECG-triggered CT with thin (2 mm), contiguous slices was performed in the region of the proximal bypass anastomoses in the ascending aorta. The data evaluation was done on axial images and on reconstructed 2D and 3D data sets. Results: The applied technique demonstrat-ed good imaging quality, which allowed evaluation of the CABG anastomoses in all cases. Overall 18 CABG anastomoses could be visualized; 17 anastomoses could be assessed as normal, non-stenotic and patent. Discussion: ECG-triggered thin-slice CT permits reliable assessment of proximal CABG anastomoses and expands the usage of CT in the evaluation of CABG.
    Notes: Zusammenfassung Hintergrund: Die computertomographische Durchgängigkeitsprüfung koronararterieller Bypässe hat sich zu einer Alternative neben dem Herzkatheter entwickelt. Die Beurteilbarkeit der Anastomosen gelingt noch nicht mit zufriedenstellender Sicherheit. Der Einsatz der prospektiven EKG-Triggerung an einem konventionellen CT ermöglicht herzphasengesteuerte Einzelschichtaufnahmen im Subsekundenbereich. Ziel der Studie war es, zu prüfen, ob der Einsatz einer EKG-Triggerung zu Verbesserungen in der Beurteilung der proximalen Bypassanastomosen führt. Methode: Bei 10 Patienten wurde nach Bypassoperation eine EKG-getriggerte CT mit dünnen (2 mm), kontinuierlichen Schichten von den proximalen Bypassanastomosen im Bereich der Aorta ascendens durchgeführt. Die Datenauswertung erfolgte an axialen Einzelschichten und nachverarbeiteten 2D- und 3D-Datensätzen. Ergebnisse: Die Untersuchungstechnik ergab in allen Fällen eine gute Bildqualität und Beurteilungsmöglichkeit der Anastomosenverhältnisse. Insgesamt wurden 18 Bypassanastomosen dargestellt. Von diesen Anastomosen konnten 17 als unauffällig, durchgängig und ohne Stenosierung gewertet werden. Schlussfolgerung: Die EGK-getriggerte CT in dünnen Schichten erlaubt eine Beurteilung der proximalen Anastomosenverhältnisse aortokoronarer Bypässe und erweitert somit das Einsatzspektrum der CT.
    Type of Medium: Electronic Resource
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